Results 51 to 60 of about 162,848 (255)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Cloning PIP genes in drought-tolerant vetiver grass and responses of transgenic VzPIP2;1 soybean plants to water stress

Biologia Plantarum, 2016
Vetiver grass [Vetiveria zizanioides (L.) Nash] displays comprehensive abiotic stress tolerance closely related to fine maintenance of plant water relation mediated by plasma membrane intrinsic proteins (PIPs).
S. B. Hu, Q. Zhou, J. An, B. J. Yu
doaj   +1 more source

Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. [PDF]

Proceedings of the National Academy of Sciences, 1995
Two water channel homologs were cloned recently from rat kidney, mercurial-insensitive water channel (MIWC) and glycerol intrinsic protein (GLIP). Polyclonal antibodies were raised against synthetic C-terminal peptides and purified by affinity chromatography.
FRIGERI, Antonio, GROPPER MA, TURCK CW, VERKMAN AS   +3 more
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The Consensus N-Myristoylation Motif of a Geminivirus AC4 Protein Is Required for Membrane Binding and Pathogenicity

Molecular Plant-Microbe Interactions, 2007
Some geminiviruses encode a small protein, AC4, whose role in pathogenesis has only recently attracted attention. A few studies have shown that this protein is involved in pathogenesis and suppresses RNA silencing.
Vincent N. Fondong, R. V. Chowda Reddy, Cheng Lu, Bertrand Hankoua, Christian Felton, Kirk Czymmek, Fidelis Achenjang   +6 more
doaj   +1 more source

Impacts of silicon and silicon nanoparticles on leaf ultrastructure and TaPIP1 and TaNIP2 gene expressions in heat stressed wheat seedlings

Biologia Plantarum, 2020
Heat stress is one of the most crucial factors affecting crop growth and productivity worldwide. So, searching for a potent eco-friendly heat stress alleviator is the main issue nowadays. The current study was conducted to assess the ameliorative effects
A.A. YOUNIS, H. KHATTAB, M.M. EMAM
doaj   +1 more source

Isolation and characterization of three maize aquaporin genes, ZmNIP2;1, ZmNIP2;4 and ZmTIP4;4 involved in urea transport [PDF]

BMB Reports, 2012
Urea-based nitrogen fertilizer was widely utilized in maizeproduction, but transporters involved in urea uptake, translocationand cellular homeostasis have not been identified.Here, we isolated three maize aquapoin genes, ZmNIP2;1,ZmNIP2;4 and ZmTIP4;4 ...
Riliang Gu, Xiaoling Chen, Yuling Zhou, Lixing Yuan   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Pathogenic podocin variants exhibit distinct defects in trafficking, membrane organization, and degradation pathways

European Journal of Cell Biology
Nephrotic syndrome is frequently associated with pathogenic variants in NPHS2 (podocin), including the common and severe R138Q substitution. Using conditionally immortalized human podocytes expressing Myc-tagged podocin variants (G92C, V180M, R138Q ...
Pei-Chen Lu, Ruth Rollason, Chia-An Chou, Valeryia Kuzmuk, Kate J. Heesom, Moin A. Saleem, Gavin I. Welsh   +6 more
doaj   +1 more source

Importance of the carboxyl terminus of FAT/CD36 for plasma membrane localization and function in long-chain fatty acid uptakes⃞

Journal of Lipid Research, 2007
This study investigates the role of the cytoplasmic C terminus of fatty acid translocase (FAT/CD36) in localization of the molecule to the plasma membrane, its insertion into lipid rafts, and its ability to enhance long-chain fatty acid uptake in ...
Nicholas S. Eyre, Leslie G. Cleland, Narendra N. Tandon, Graham Mayrhofer   +3 more
doaj   +1 more source