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Exosomes as Cellular Communicators and Therapeutic Agents in Orthopedic Diseases: From Mechanisms to Intervention. [PDF]
Int J NanomedicineZhang J +6 more
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Plasma membrane repair in plants
Trends in Plant Science, 2009Resealing is the membrane-repair process that enables cells to survive disruption, preventing the loss of irreplaceable cell types and eliminating the cost of replacing injured cells. Given that failure in the resealing process in animal cells causes diverse types of muscular dystrophy, plasma membrane repair has been extensively studied in these ...
Arnaldo L, Schapire +2 more
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Annexins Bend Wound Edges during Plasma Membrane Repair
Current Medicinal Chemistry, 2020The plasma membrane of eukaryotic cells defines the boundary to the extracellular environment and, thus provides essential protection from the surroundings. Consequently, disruptions to the cell membrane triggered by excessive mechanical or biochemical stresses pose fatal threats to cells, which they need to cope with to survive.
Simonsen, Adam Cohen +2 more
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Annexins in plasma membrane repair
Biological Chemistry, 2016Abstract Disruption of the plasma membrane poses deadly threat to eukaryotic cells and survival requires a rapid membrane repair system. Recent evidence reveal various plasma membrane repair mechanisms, which are required for cells to cope with membrane lesions including membrane fusion and replacement strategies, remodeling of cortical ...
Theresa Louise, Boye, Jesper, Nylandsted
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Plasma Membrane Disruption: Repair, Prevention, Adaptation
Annual Review of Cell and Developmental Biology, 2003▪ Abstract  Many metazoan cells inhabit mechanically stressful environments and, consequently, their plasma membranes are frequently disrupted. Survival requires that the cell rapidly repair or reseal the disruption. Rapid resealing is an active and complex structural modification that employs endomembrane as its primary building block, and ...
Paul L, McNeil, Richard A, Steinhardt
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Dealing with damage: Plasma membrane repair mechanisms
Biochimie, 2014Eukaryotic cells have developed repair mechanisms, which allow them to reseal their membrane in order to prevent the efflux of cytoplasmic constituents and the uncontrolled influx of calcium. After injury, the Ca(2+)-concentration gradient fulfils a dual function: it provides guidance cues for the repair machinery and directly activates the molecules ...
Annette, Draeger +4 more
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