Plasma membrane disruptions with different modes of injurious mechanical ventilation in normal rat lungs [PDF]
, 2012 Plasma membrane disruptions are caused by excessive mechanical stress and thought to be involved in inflammatory mediator upregulation. Presently, plasma membrane disruption formation has been studied only during mechanical ventilation with large tidal ...
Edgardo DʼAngelo +7 more
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Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics
Advanced Science, Volume 13, Issue 18, 27 March 2026.This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu +6 more
wiley +1 more source
Calcium-dependent plasma membrane repair requires m- or μ-calpain, but not calpain-3, the proteasome, or caspases [PDF]
, 2009 Mechanically damaged plasma membrane undergoes rapid calcium-dependent resealing that appears to depend, at least in part, on calpain-mediated cortical cytoskeletal remodeling. Cells null for Capns1, the non-catalytic small subunit present in both m- and
Spencer, Melissa J. +8 more
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Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.NINJ1 mediates PMR in cardiovascular cell death, releasing DAMPs that amplify vascular inflammation. Dual NINJ1 paradox: membrane‐bound form drives endothelial NF‐κB/CXCL‐8 inflammation while soluble form provides atheroprotection. Pericyte NINJ1 regulates the critical balance between angiogenic sprouting and vessel maturation in ischaemic tissues ...
Muhammad Mamunur Rashid Mahib
wiley +1 more source
Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair [PDF]
, 2011 Eukaryotic cells possess a universal repair machinery that ensures rapid resealing of plasma membrane disruptions. Before resealing, the torn membrane is submitted to considerable tension, which functions to expand the disruption.
Ernst Pöschl +19 more
core +1 more source
Review: Annexin-A5 and cell membrane repair [PDF]
, 2015 Annexins are soluble proteins that bind to biological membranes containing negatively charged phospholipids, principally phosphatidylserine, in a Ca2+-dependent manner.
GOUNOU, Celine +6 more
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The membrane repair response masks membrane disturbances caused by cell-penetrating peptide uptake [PDF]
, 2009 Although cell-penetrating peptides are able to deliver cargo into cells, their uptake mechanism is still not fully understood and needs to be elucidated to improve their delivery efficiency.
Hällbrink, Mattias, +4 more
core +1 more source
Kollidon VA64, a Membrane-Resealing Agent, Reduces Histopathology and Improves Functional Outcome after Controlled Cortical Impact in Mice [PDF]
, 2011 Loss of plasma membrane integrity is a feature of acute cellular injury/death in vitro and in vivo. Plasmalemma-resealing agents are protective in acute central nervous system injury models, but their ability to reseal cell membranes in vivo has not ...
Mykol Larvie +8 more
core +1 more source
Plasma membrane damage sensing and repairing. Role of heterotrimeric G-proteins and the cytoskeleton [PDF]
, 2011 Different toxic agents, derived from bacteria, viruses or cells of the immune system, as well as mechanical forces generated during cell locomotion are able to open pores in the cell plasma membrane.
Maria Antonietta Panaro +9 more
core +1 more source
NOVEL TECHNIQUES FOR IN VIVO CHARACTERIZATION OF SHORT PEPTIDES AND PROTEINS IN MEMBRANE PERMEABILIZATION AND SIGNAL TRANSDUCTION [PDF]
, 2012 My scientific interest is focused on the field of cellular electrical activity, ranging from the study of intracellular enzymatic processes to the characterization of new generation of drugs.
Aquila, Marco
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