Results 71 to 80 of about 2,406 (159)
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam +4 more
wiley +1 more source
Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair [PDF]
Rapid plasma membrane resealing is essential for cellular survival. Earlier studies showed that plasma membrane repair requires Ca2+-dependent exocytosis of lysosomes and a rapid form of endocytosis that removes membrane lesions.
Vincent Idone +17 more
core +1 more source
Current advances in liposome–extracellular vesicle hybrid systems for cancer drug delivery
Liposome–extracellular vesicle hybrids combine synthetic stability with biological targeting capability. Hybrid nanovesicles enhance drug loading efficiency and tumour‐specific delivery. Advanced fusion strategies improve membrane integration and functional preservation.
Arina Habibi +6 more
wiley +1 more source
Modeling Synaptic Maturation From Growth Cone to Synapse in Human Organoids
Synapses are implicated in several neurological disorders and psychiatric diseases. The emergence and wide use of neural organoids provide a new opportunity to study human synapses in healthy and disease settings. Therefore, we developed a simple method for the enrichment of synaptosomes and growth cone particles from forebrain organoids. The method is
Marie S. Øhlenschlæger +16 more
wiley +1 more source
The repeated bout effect (RBE) is an adaptive response to a subsequent injury; muscle physiological or pathological state determines the magnitude and trajectory of strength adaptation. Abstract Skeletal muscle exhibits remarkable plasticity following injury, yet most research has focused on responses to a single bout of eccentric contractions.
Cory W. Baumann +3 more
wiley +1 more source
Membrane interaction of cyanobacterial and chloroplast ESCRT‐III proteins
SUMMARY More than three decades ago, the inner membrane‐associated protein of 30 kDa (IM30), also known as Vipp1, was identified in pea chloroplasts to bind to the chloroplast inner envelope membrane. IM30/Vipp1 is a membrane‐associated and soluble stromal protein and is proposed to mediate vesicle formation.
Mirka Kutzner +4 more
wiley +1 more source
Damage‐triggered actin polymerization stabilizes membrane pores in giant unilamellar vesicles (GUVs). Membrane poration drives divalent cation influx, inducing rapid F‐actin assembly at the defect site. The resulting actin plug mechanically arrests pore expansion and preserves vesicle morphology, recapitulating the “plugging” phase of single‐cell ...
Huong Thanh Nguyen +3 more
wiley +1 more source
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz +10 more
wiley +1 more source
Neuronal survival and membrane resealing of cultured rat septal neurons after laser-induced neurite transection [PDF]
Fetal rat septal neurons were grown in culture pre-treated with lung fibroblast conditioned medium at a final plating density of 1000 to 5000 cells per square centimeter.
Xie, Xiao-Yi
core
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos +12 more
wiley +1 more source

