A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji +13 more
wiley +1 more source
Delivery Systems for Therapeutic Genome Editing: Challenges, Innovations, and Future Perspectives
Schematic illustration of four emerging CRISPR–Cas delivery platforms defined by distinct design principles and structural features: virus‐mimicking nanosystems (e.g., VLPs), cell‐derived extracellular vesicles, cell‐penetrating peptides, and stimuli‐responsive scaffolds. These platforms enable spatiotemporally controlled delivery of RNPs, mRNA, or DNA
Meijia Yang +9 more
wiley +1 more source
The septin cytoskeleton is required for plasma membrane repair
Plasma membrane repair is a fundamental homeostatic process of eukaryotic cells. Here, we report a new function for the conserved cytoskeletal proteins known as septins in the repair of cells perforated by pore-forming toxins or mechanical disruption ...
M Isabella Prislusky +9 more
doaj +1 more source
Hybrid modeling of electroporation and impedance spectroscopy for label free characterization of stem cells. [PDF]
Sherif S, Ghallab YH, Ismail Y.
europepmc +1 more source
Simultaneous Whole-Cell Recording and Calcium Imaging Does Not Reveal Electrically Coupled Neurons in <i>Xenopus</i> Tadpoles. [PDF]
Xu-Ying B, Zwart MF, Li WC.
europepmc +1 more source
Biophysical principles of pulsed field ablation. [PDF]
Apollonio F +9 more
europepmc +1 more source
MG53, a Regenerative Myokine Linking Skeletal Muscle to Cardiac Repair. [PDF]
Chen Y, Lee KE, Kim J, Ko JK, Park KH.
europepmc +1 more source
To Die or Not to Die: How Sublethal Damage Rewires Cell Fate and Implications for Sepsis. [PDF]
Hu Z +7 more
europepmc +1 more source
Application of nisin as a potential drug candidate for electrochemotherapy. [PDF]
Michel O +9 more
europepmc +1 more source

