Results 31 to 40 of about 2,379 (121)

Harnessing bacterial extracellular vesicles for bone and cartilage organoids

BMEMat, EarlyView.
This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu, Xukun Lv, Ting Cheng, Lei Yan, Yuxiao Lai, Keying Guo, Yingying Jing, Hao Shen, Jiacan Su   +8 more
wiley   +1 more source

Identification of Yeast Protein Sequences With Similarity to the ESCRT‐III Protein Snf7

Yeast, EarlyView.
ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
Thomas Brune, Ralf Kölling
wiley   +1 more source

Cell wounding activates phospholipase D in primary mouse keratinocytes

Journal of Lipid Research, 2013
Plasma membrane disruptions occur in mechanically active tissues such as the epidermis and can lead to cell death if the damage remains unrepaired. Repair occurs through fusion of vesicle patches to the damaged membrane region. The enzyme phospholipase D
Senthil N. Arun, Ding Xie, Amber C. Howard, Quincy Zhong, Xiaofeng Zhong, Paul L. McNeil, Wendy B. Bollag   +6 more
doaj   +1 more source

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

Journal of Applied Polymer Science, Volume 143, Issue 41, November 5, 2026.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis, Andrew Adamatzky   +1 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, Volume 38, Issue 61, 2 November 2026.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Annexins: players of single cell wound healing and regeneration

Communicative & Integrative Biology, 2019
Cell life is defined by a thin 4 nm plasma membrane, which separates the interior of a cell from its environment. Thus, disruption of the plasma membrane poses a critical risk to cells, which requires immediate repair to avoid uncontrolled osmotic lysis ...
Swantje Christin Häger, Jesper Nylandsted   +1 more
doaj   +1 more source

After delivery: How recipient cells shape the fate and function of transplanted mitochondria

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Recipient‐cell handling shapes how transplanted mitochondria contribute after delivery, linking donor competence, recipient state and exposure duration to intracellular fate. The framework matches transient rescue, sustained functional support and durable mitochondrial DNA correction to the evidence and product attributes required for each therapeutic ...
Zhi‐Yuan Zhang, Bo‐Quan Qin, Shi‐Zhou Wu, Hui Zhang   +3 more
wiley   +1 more source

Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury.

PLoS Genetics, 2017
Genetic disruption of the dystrophin complex produces muscular dystrophy characterized by a fragile muscle plasma membrane leading to excessive muscle degeneration.
Mattia Quattrocelli, Joanna Capote, Joyce C Ohiri, James L Warner, Andy H Vo, Judy U Earley, Michele Hadhazy, Alexis R Demonbreun, Melissa J Spencer, Elizabeth M McNally   +9 more
doaj   +1 more source

Affinity for, and localization of, PEG-functionalized silica nanoparticles to sites of damage in an ex vivo spinal cord injury model

Journal of Biological Engineering, 2012
Background Traumatic spinal cord injury (SCI) leads to serious neurological and functional deficits through a chain of pathophysiological events. At the molecular level, progressive damage is initially revealed by collapse of plasma membrane organization
Chen Bojun, Zuberi Mahvash, Borgens Richard Ben, Cho Youngnam   +3 more
doaj   +1 more source

Caveolae disassemble upon membrane lesioning and foster cell survival

iScience
Summary: Repair of lesions in the plasma membrane is key to sustaining cellular homeostasis. Cells maintain cytoplasmic as well as membrane-bound stores of repair proteins that can rapidly precipitate at the site of membrane lesions.
Martin Štefl, Masanari Takamiya, Volker Middel, Miyase Tekpınar, Karin Nienhaus, Tanja Beil, Sepand Rastegar, Uwe Strähle, Gerd Ulrich Nienhaus   +8 more
doaj   +1 more source