Results 31 to 40 of about 1,632,079 (301)

Interaction of antithrombin III with surface-immobilized albumin-heparin conjugates [PDF]

open access: yes, 1995
The interaction between antithrombin III (ATIII) and albumin-heparin conjugates covalently coupled onto carboxylated polystyrene beads either in buffer containing albumin or in plasma was studied using 14C-labeled ATIII.
Delden, C.J. van   +2 more
core   +3 more sources

Benefit of Apabetalone on Plasma Proteins in Renal Disease. [PDF]

open access: yes, 2018
Introduction:Apabetalone, a small molecule inhibitor, targets epigenetic readers termed BET proteins that contribute to gene dysregulation in human disorders. Apabetalone has in vitro and in vivo anti-inflammatory and antiatherosclerotic properties.
Gilham, Dean   +11 more
core   +2 more sources

Pathophysiology of elevated ascites fluid cholesterol in malignant ascites [PDF]

open access: yes, 1992
The existence of marked elevations of ascitic fluid cholesterol has been observed in patients with peritoneal carcinomatosis compared to patients with cirrhosis and has been found useful in differential diagnosis.
Alexander L. Gerbes   +27 more
core   +1 more source

Comparative proteomic analysis of plasma proteins in patients with age-related macular degeneration [PDF]

open access: yesInternational Journal of Ophthalmology, 2014
AIM: To find the significant altered proteins in age-related macular degeneration (AMD) patients as potential biomarkers of AMD.METHODS: A comparative analysis of the protein pattern of AMD patients versus healthy controls was performed by means of ...
Xin-Rong Xu   +6 more
doaj   +1 more source

Micro-scale blood plasma separation: from acoustophoresis to egg-beaters [PDF]

open access: yes, 2013
Plasma is a rich mine of various biomarkers including proteins, metabolites and circulating nucleic acids. The diagnostic and therapeutic potential of these analytes has been quite recently uncovered, and the number of plasma biomarkers will still be ...
Kersaudy-Kerhoas, Maïwenn   +1 more
core   +1 more source

Magnetically Levitated Plasma Proteins [PDF]

open access: yesAnalytical Chemistry, 2020
Surprisingly, the densities of proteins in solution, which are important fundamental biophysical quantities, have not been accurately measured. The lack of such data can limit meaningful interpretation of physical and chemical features of proteins and enzymes. Here, we demonstrate a new technique using superparamagnetic iron oxide nanoparticles (SPIONs)
Ali Akbar Ashkarran   +2 more
openaire   +2 more sources

Proteomic Exploration of Plasma Exosomes and Other Small Extracellular Vesicles in Pediatric Hodgkin Lymphoma: A Potential Source of Biomarkers for Relapse Occurrence

open access: yesDiagnostics, 2021
Exosomes and other small extracellular vesicles (EVs) are potential sources of cancer biomarkers. Plasma-derived EVs have not yet been studied in pediatric Hodgkin lymphoma (HL), for which predictive biomarkers of relapse are greatly needed.
Ombretta Repetto   +12 more
doaj   +1 more source

Detection of surface-adsorbed (lipo)proteins by means of a two-step enzyme-immunoassay: a study on the Vroman effect [PDF]

open access: yes, 1990
In view of reports on the involvement of high-molecular-weight (HMW) kininogen and high-density lipoprotein (HDL) in the Vroman effect, we studied the adsorption of fibrinogen, HMW kininogen, HDL and several other proteins from pooled human plasma and ...
Aken, W.G. van   +3 more
core   +2 more sources

Analysis of Destruction Process of the Primary Thrombus Under the Influence of the Blood Flow

open access: yesJournal of Biomechanical Science and Engineering, 2007
Stokesian dynamics method based on the approximation of the additivity of velocities was employed to analyze the mechanical behavior of the primary thrombus under the blood flow.
Koichiro YANO   +5 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

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