Results 11 to 20 of about 4,009,281 (300)

Depletion of Abundant Plasma Proteins and Limitations of Plasma Proteomics

, 2016
Immunoaffinity depletion with antibodies to the top 7 or top 14 high-abundance plasma proteins is used to enhance detection of lower abundance proteins in both shotgun and targeted proteomic analyses.
Robbert J. C. Slebos (1272318), Stephen E. Stein (1309986), Chengjian Tu (1314213), Paul A. Rudnick (1868998), Misti Y. Martinez (2263045), Daniel C. Liebler (1264215), Kristin L. Cheek (2186953)   +6 more
core   +7 more sources

Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]

, 2002
Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Day, S., Day, SP, Caslake, MJ, Chaudhry, MA, Chaudhry, M.A., Muriithi, E.W., Wheatley, DJ, Muriithi, EW, Belcher, P.R., Belcher, PR   +9 more
core   +4 more sources

The road not taken: Less traveled roads from the TGN to the plasma membrane [PDF]

, 2015
: The trans-Golgi network functions in the distribution of cargo into different transport vesicles that are destined to endosomes, lysosomes and the plasma membrane. Over the years, it has become clear that more than one transport pathway promotes plasma
Anne Spang, Spang, Anne, Spang A
core   +1 more source

Deiminated Proteins in Extracellular Vesicles and Plasma of Nurse Shark (Ginglymostoma cirratum) - Novel Insights into Shark Immunity [PDF]

, 2019
Peptidylarginine deiminases (PADs) are phylogenetically conserved calcium-dependent enzymes which post-translationally convert arginine into citrulline in target proteins in an irreversible manner, causing functional and structural changes in target ...
Lange, S., Kraev, Igor, Criscitiello, M.F., Criscitiello, Michael F., Lange, Sigrun, Kraev, I.   +5 more
core   +1 more source

Profiling plasma peptides for the identification of potential ageing biomarkers in Chinese Han adults [PDF]

, 2012
Advancing age is associated with cardiovascular disease, diabetes mellitus and cancer, and shows significant inter-individual variability. To identify ageing-related biomarkers we performed a proteomic analysis on 1890 Chinese Han individuals, 1136 males
Manshu Song (153063), Xinwei Yu (153054), Feifei Zhao, Li, Y., Manshu Song, Jingjing Wu (153040), Alan H Bittles, Jiapeng Lu (153024), Zhang, Y., Jiapeng Lu, Wei Wang, Wang, Youxin, Yu, Xinwei, Meng, S., Wu, Jingjing, Song, Manshu, Huang, Y., Qingwei Ma (153058), Chang, Naibai, Shijiao Meng, Meng, Shijiao, Shijiao Meng (153050), Wang, Y., Naibai Chang, Xinwei Yu, Zhang, Youjun, Wang, Wei, Huang, Yuqing, Naibai Chang (153067), Yuqing Huang, Qingwei Ma, Yujun Zhang, Youxin Wang (153032), Yuqing Huang (153028), Alan H. Bittles (153071), Li, Yan, Yan Li (23143), Wei Wang (17594), Zhao, Feifei, Chang, N., Bittles, A.H., Yan Li, Song, M., Yujun Zhang (118792), Yu, X., Feifei Zhao (153044), Ma, Qingwei, Wu, J., Zhao, F., Lu, Jiapeng, Bittles, Alan H., Lu, J., Jingjing Wu, Ma, Q., Youxin Wang, Wang, W., Yu Xinwei, Wang Wei, Wu Jingjing, Huang Yuqing, Song Manshu, Lu Jiapeng, Ma Qingwei, Zhang Yujun, Chang Naibai, Li Yan, Bittles Alan H., Zhao Feifei, Wang Youxin, Meng Shijiao   +69 more
core   +1 more source

Plasma membrane compartmentation in Saccharomyces cerevisiae [PDF]

, 2009
In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
core   +1 more source

Effect of Low-Temperature Plasma Jet on Thermal Stability and Physical Structure of Type I Collagen [PDF]

, 2012
This work is devoted to the characterization of type I collagen treated by a low-temperature plasma jet generated in ambient air to determine whether the resulting fibrous material is structurally preserved or reinforced.
Yousfi, Mohammed, Gardou, Jean-Pierre, Merbahi, Nofel, Delaunay, Florian, Lacabanne, Colette, Samouillan, Valérie, Dandurand, Jany   +6 more
core   +1 more source

14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins [PDF]

, 2013
Signaling through G proteins normally involves conformational switching between GTP- and GDP-bound states. Several Rho GTPases are also regulated by RhoGDI binding and sequestering in the cytosol.
Riou, P, O’Reilly, N., George, Roger, Ritu Garg, McColl, Brad, Ganka Bineva, Kjær, S., Svend Kjær, Garg, R, Bineva, G., Thompson, AJ, Reymond, N, Philippe Riou, Purkiss, Andrew, Nicola O’Reilly, Parker, Peter J, Brad McColl, Peter J. Parker, Neil Q. McDonald, Parker, Peter J.; id_orcid, Riou, P., Purkiss, A, Parker, PJ, Thompson, A.J., McColl, B, Cain, RJ, Parker, P.J., Kjær, Svend, McColl, B., Andrew Purkiss, O’Reilly, N, Kjær, S, Garg, R., Garg, Ritu, O'Reilly, Nicola, Anne J. Ridley, Cain, Robert J, Robert J. Cain, McDonald, Neil Q, Ridley, Anne J, Bineva, G, Ridley, A.J., Purkiss, Andrew G., Nicolas Reymond, George, R., Thompson, Andrew J, Reymond, N., Reymond, Nicolas, Bineva, Ganka, McDonald, NQ, Riou, Philippe, Andrew J. Thompson, Ridley, AJ, Kjaer, Svend, George, R, Cain, R.J., Roger George, McDonald, Neil Q., Thompson, Andrew J., Cain, Robert J., Ridley, Anne J.   +60 more
core   +1 more source

Molecular Mechanisms of the Interactions of N-(2-Hydroxypropyl)methacrylamide Copolymers Designed for Cancer Therapy with Blood Plasma Proteins

Pharmaceutics, 2020
The binding of plasma proteins to a drug carrier alters the circulation of nanoparticles (NPs) in the bloodstream, and, as a consequence, the anticancer efficiency of the entire nanoparticle drug delivery system.
Larisa Janisova, Andrey Gruzinov, Olga V. Zaborova, Nadiia Velychkivska, Ondřej Vaněk, Petr Chytil, Tomáš Etrych, Olga Janoušková, Xiaohan Zhang, Clement Blanchet, Christine M. Papadakis, Dmitri I. Svergun, Sergey K. Filippov   +12 more
doaj   +1 more source

Plasma Protein Levels Analysis in Multiple Sclerosis Sardinian Families Identified C9 and CYP24A1 as Candidate Biomarkers

Life, 2022
Here we investigate protein levels in 69 multiple sclerosis (MS) cases and 143 healthy controls (HC) from twenty Sardinian families to search for promising biomarkers in plasma.
Andrea Nova, Teresa Fazia, Ashley Beecham, Valeria Saddi, Marialuisa Piras, Jacob L. McCauley, Carlo Berzuini, Luisa Bernardinelli   +7 more
doaj   +1 more source