Results 71 to 80 of about 1,431,190 (302)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

On the development of a deployable cold plasma endoscope

open access: yes, 2018
A novel non-thermal atmospheric-pressure plasma jet source for endoscopic application is presented. Specific challenges in the endoscopic plasma source development, such as small dimensions, flexibility, operation in half-closed cavities, and the ...
Thalita M.C. Nishime   +9 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Transport properties of disordered 2D complex plasma crystal

open access: yes, 2018
In this work, we investigate numerically the transport properties of a 2D complex plasma crystal using diffusion of coplanar dust lattice waves. In the limit where the Hamiltonian interactions can be decoupled from the non-Hamiltonian effects, we ...
Busse, Kyle   +8 more
core   +1 more source

THE INFLUENCE OF MODERN PLASMA SUBSTITUTES ON THE COURSE OF ABDOMINAL COMPARTMENT SYNDROME IN PATIENTS WITH ABDOMINAL SEPSIS

open access: yesВестник хирургии имени И.И. Грекова, 2018
The changes of intra-abdominal pressure (IAP) were followed up in 244 patients with abdominal sepsis after operation. The influence of liquid «resuscitation» with different types of plasma substitutes on the rates of IAP was studied and the dependence of
S. V. Kursov
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Formulation and Evaluation of Iron-Rich Chocolate Spread from Sugarcane Syrup and Sunflower Seeds

open access: yesJournal of Food Quality, 2023
Anemia is widely recognized as a serious public health problem and the most common type of micronutrient deficiency globally. Developing a product enriched with iron to overcome this issue has received excessive attention.
Heba Sayed Mostafa
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

BEHAVIOR OF MULTISUBSTITUTED HYDROXYAPATITES IN WATER AND SIMULATED BODY FLUID

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2017
Nanostructured hydroxyapatite (HAP) and three multiple substituted HAPs, containing Mg, Zn, Sr and Si were synthesized by a wet precipitation method.
Oana CADAR   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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