Results 81 to 90 of about 59,710 (300)

Predicting optimal hematocrit in silico [PDF]

open access: yes, 2018
Optimal hematocrit $H_o$ maximizes oxygen transport. In healthy humans, the average hematocrit $H$ is in the range of 40-45$\%$, but it can significantly change in blood pathologies such as severe anemia (low $H$) and polycythemia (high $H$). Whether the
Audemar, Vassanti   +11 more
core   +7 more sources

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Current concepts in platelet transfusion

open access: yesAsian Journal of Transfusion Science, 2009
This is the era of component therapy. Therefore there is a need for rational use of platelet concentrate. Lot of knowledge has been added recently in the field of platelet specially about the platelet rich plasma and its application in clinical practice.
Mohanty Dipika
doaj  

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Clean-Label Strategies for the Replacement of Nitrite, Ascorbate, and Phosphate in Meat Products: A Review

open access: yesFoods
The clean-label movement has markedly increased consumer demand for meat products free from synthetic additives, such as sodium nitrite, ascorbate, and phosphate.
Minhyeong Kim   +4 more
doaj   +1 more source

トウモロコシ由来の新しい飼料原料のニジマスにおける栄養価評価に関する研究 [PDF]

open access: yes, 2015
東京海洋大学博士学位論文 平成25年度(2013) 応用生命科学 課程博士 甲第301号指導教員: 佐藤秀一全文公表年月日: 2016-03 ...
Prachom Noratat
core   +1 more source

Multiband and impurity effects in infrared and optical spectra of MgB2

open access: yes, 2007
A short review of the optical and far-infrared measurements on MgB$_{2}$ is given. Multiband and multigap effects are analyzed by comparing optical properties with other experiments and {\em ab initio} calculations.
A.B. Kuzmenko   +63 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Providing the Gift of Life: Canadian Medical Practitioners and the Treatment of Shock on the Battlefield [PDF]

open access: yes, 2012
The story of Ambroise Pare’s discovery has been told often; of how, during Francis I’s campaign against Turin in 1536-37, he ran out of the oil medical practitioners used to cauterize the stumps of amputees and used an herbal remedy and ligatures instead;
Rawling, Bill
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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