Results 151 to 160 of about 4,892,488 (246)

B Cell Deficiency Protects Against the Development of c‐MET and Beta‐Catenin Driven Hepatocellular Carcinoma in Mice

Cell Biology International, Volume 50, Issue 11, November 2026.
ABSTRACT Hepatocellular carcinoma (HCC), a lethal form of liver cancer, continues to show rising mortality rates despite advancements in immunotherapies. This highlights the need for more effective treatments. Recent studies linked the presence of B cells within human tumors, including HCC, to improved responses to immunotherapy and better prognoses ...
Fang Wang, Eun Bi Lim, Rehan Mehta, Yee Ling Wu   +3 more
wiley   +1 more source

Immune Regulation by Regnase‐1 and Related Endoribonucleases

European Journal of Immunology, Volume 56, Issue 11, November 2026.
Regnase‐1 couples immune signaling to stem‐loop‐mediated mRNA decay. Its biological output depends on cellular and tissue context, determining whether it restrains inflammation, maintains tissue homeostasis, or suppresses inflammation‐associated tumorigenesis.
Takuya Uehata, Osamu Takeuchi
wiley   +1 more source

Plant‐Derived Probiotics From Fermented Foods: Current Evidence on Antiviral Mechanisms and Gut–Lung Axis Modulation

Food Frontiers, Volume 7, Issue 6, November 2026.
Plant‐derived probiotics from fermented foods exert anti‐respiratory virus effects via immune regulation, antiviral metabolites, and gut–lung axis, highlighting their advantages, key technologies, and application prospects. ABSTRACT Respiratory viral infections represent a major global public health threat, causing widespread morbidity, mortality, and ...
Yinghao Xing, Yaoyuan Hu, Yingying Ma, Peng Yao, Jingjing Jiang, Jiao Guo, Shuangmei Liu   +6 more
wiley   +1 more source

Proof‐of‐Concept of an Intravital Murine Model to Observe the Spatiotemporal Distribution of Immune Cells Constituting the Foreign Body Response and Biomaterial Associated Infections

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 11, November 2026.
Development of a murine intravital ‘FBR‐through‐a‐window’ model enables longitudinal imaging of the spatiotemporal distribution of macrophages, neutrophils, myofibroblasts, and collagen during the foreign body response (FBR) and biomaterial‐associated infections (BAI). ABSTRACT Biomaterials are used more and more for permanent implantation in humans to
Elles C. Boonstra, Paul C. Jutte, Henny C. van der Mei, Aishi S. Satapathy, Anouk H. G. Wolters, Theo G. van Kooten, Jelmer Sjollema   +6 more
wiley   +1 more source

Multi‐Omics Insights Into Circulating T‐Cell Metabolic Reprogramming and Treg Dysfunction in Moyamoya Disease

MedComm, Volume 7, Issue 11, November 2026.
The comprehensive study design is illustrated. A multi‐omics approach was used to characterize T‐cell metabolic alterations in MMD. By integrating mass cytometry (CyTOF), single‐cell RNA sequencing (scRNA‐seq), bulk RNA‐seq, metabolomics, and flow cytometry, we aimed to elucidate metabolic reprogramming in circulating T cells and Treg dysfunction in ...
Zhiyao Zheng, Qiheng He, Xinyu Ma, Bojian Zhang, Junsheng Li, Chenglong Liu, Siqi Mou, Wei Sun, Xiangjun Shi, Wenjing Wang, Dong Zhang, Peicong Ge, Jizong Zhao   +12 more
wiley   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

Anti-BCMA immunotherapies deplete plasmacytoid dendritic cells and impair antiviral immunity in multiple myeloma. [PDF]

Hemasphere
Venglar O, Radova E, Warmuzova M, Bilek D, Kudelkova M, Jasinkova K, Muronova L, Broskevicova L, Kapustova V, Vrana J, Novakova T, Karasova K, Hornakova M, Popkova T, Mihalyova J, Plonkova H, Simicek M, Radocha J, Sevcikova T, Zihala D, Bago J, Hajek R, Jelinek T.   +22 more
europepmc   +1 more source

Parenteral CHIKV mRNA Vaccination Reshapes the Gut Microbial, Metabolic, and Immune Landscapes

MedComm, Volume 7, Issue 11, November 2026.
This study provides multi‐omics evidence that parenteral mRNA vaccination against CHIKV, even in the absence of viral infection, can profoundly remodel the host intestinal ecosystem—recapitulating key microbial, metabolic, and GI immune features typically associated with active CHIKV infection, characterized by enrichment of Segatella copri, activation
Hongyu Chen, Wenhao Xie, Yun Yang, Cong Tang, Xiaoming Liang, Yuxia Yuan, Junbin Wang, Yanan Zhou, Hao Yang, Qing Huang, Wenqi Quan, Wenhai Yu, Haixuan Wang, Daoju Wu, Youchun Wang, Shuaiyao Lu   +15 more
wiley   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, Volume 183, Issue 21, Page 6261-6290, November 2026.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Editorial: Modulating plasmacytoid dendritic cells: balancing cancer immunity and tumor progression. [PDF]

Front Immunol
Monti M, Aspord C, Tripodo C, Vermi W.
europepmc   +1 more source