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Biological Functions of Plasmalogens
2020Plasmalogens (Pls) are one kind of phospholipids enriched in the brain and other organs. These lipids were thought to be involved in the membrane bilayer formation and anti-oxidant function. However, extensive studies revealed that Pls exhibit various beneficial biological activities including prevention of neuroinflammation, improvement of cognitive ...
Md Shamim, Hossain +2 more
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The biophysical properties of ethanolamine plasmalogens revealed by atomistic molecular dynamics simulations [PDF]
Given the importance of plasmalogens in cellular membranes and neurodegenerative diseases, a better understanding of how plasmalogens affect the lipid membrane properties is needed.
Tomasz Rog, Artturi Koivuniemi
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Composition of plasmalogens in serum lipoproteins from patients with non-alcoholic steatohepatitis and their susceptibility to oxidation [PDF]
Background: Plasmalogens are ether phospholipids (PL) with an alkenyl group including vinyl ether bound at the sn-1 position and a polyunsaturated fatty acid bound at the sn-2 position, and are susceptible to oxidation.
Megumi Nishimukai +2 more
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Chromatographic analysis of plasmalogens
Chromatographic Reviews, 1968Abstract Chromatography has been widely used in the studies on plasmalogens. It has been used for the following purposes: 1. A rapid and simultaneous determination in total lipid extracts of phosphatide classes and their constituent plasmalogens by reaction two-dimensional thin-layer chromatography. 2.
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Ingestion of plasmalogen markedly increased plasmalogen levels of blood plasma in rats
Lipids, 2003AbstractPlasmalogens, a subclass of phospholipids, are widely distributed in human and animals, and are taken into the body as food. However, no data exist on the intestinal absorption or fate of ingested plasmalogen. Here, we determined whether dietary plasmalogen is absorbed and whether blood and tissue concentrations increased in normal male Wistar ...
Megumi, Nishimukai +2 more
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Analysis of Plasmalogen Species in Foodstuffs
Lipids, 2016AbstractEthanolamine plasmalogen (PlsEtn), which is present at high levels in brains, is believed to be involved in neuronal protection. The present study was performed to search for PlsEtn resources in foodstuffs. The foodstuffs examined showed a wide range of PlsEtn contents from 5 to 549 μmol/100 g wet wt.
Shinji, Yamashita +6 more
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Pathway for Hydrolysis of Plasmalogens in Brain
1978The ethanolamine plasmalogens in brain have a substantial rate of turnover (Horrocks et al., 1976). Hydrolytic degradation of the plasmalogen molecule could begin at any position. Evidence for phospholipase C (EC 3.1.4.3) in brain has been reported (Williams et al., 1973; Abra and Quinn, 1975).
L A, Horrocks, S C, Fu
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Reaction of Mercuric Chloride with Plasmalogen
Nature, 1959IT has been found that aqueous mercuric chloride reacts with the enol-ether double bond of plasmalogen1 to form a mercury-organic compound. This reaction clarifies the mercuric chloride catalysis in the Feulgen-Voit-Schiff identification of plasmalogen2.
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Plasmalogens: biosynthesis and functions
Progress in Lipid Research, 2001N, Nagan, R A, Zoeller
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