Distinct architectural requirements for the parS centromeric sequence of the pSM19035 plasmid partition machinery [PDF]
eLife, 2022 Three-component ParABS partition systems ensure stable inheritance of many bacterial chromosomes and low-copy-number plasmids. ParA localizes to the nucleoid through its ATP-dependent nonspecific DNA-binding activity, whereas centromere-like parS-DNA and
Andrea Volante +2 more
doaj +2 more sources
Stabilization of the virulence plasmid pSLT of Salmonella Typhimurium by three maintenance systems and its evaluation by using a new stability test [PDF]
Frontiers in Molecular Biosciences, 2016 Certain Salmonella enterica serovars belonging to subspecies I carry low-copy-number virulence plasmids of variable size (50-90 kb). All of these plasmids share the spv operon, which is important for systemic infection.
Damián Lobato-Márquez +4 more
doaj +3 more sources
Plasmid partition: sisters drifting apart. [PDF]
EMBO J, 2013 Remarkably little is known about how bacterial chromosomes and their plasmids are partitioned to daughter cells prior to cell division, despite extensive experimentation and bioinformatic analysis. An in vitro study described in the current issue of The EMBO Journal recapitulates many features of plasmid partition in vivo and provides insight into how ...
Sherratt D.
europepmc +4 more sources
Type I partition-related proteins enhance conjugative transfer through transcriptional activation and oriT region binding [PDF]
mBioPlasmid partitioning and bacterial conjugation are critical processes ensuring plasmid maintenance and dissemination, respectively, within bacterial populations.
Kouhei Kishida +9 more
doaj +2 more sources
Analysis of virus genomes from glacial environments reveals novel virus groups with unusual host interactions [PDF]
Frontiers in Microbiology, 2015 Microbial communities in glacial ecosystems are diverse, active, and subjected to strong viral pressures and infection rates. In this study we analyse putative virus genomes assembled from three dsDNA viromes from cryoconite hole ecosystems of Svalbard ...
Christopher Mark Bellas +2 more
doaj +5 more sources
Reconstitutions of plasmid partition systems and their mechanisms [PDF]
Plasmid, 2017 Bacterial plasmid and chromosome segregation systems ensure that genetic material is efficiently transmitted to progeny cells. Cell-based studies have shed light on the dynamic nature and the molecular basis of plasmid partition systems.
Brooks, A.C., Hwang, L.C.
core +4 more sources
Interplay between plasmid partition and postsegregational killing systems. [PDF]
J Bacteriol, 2004 ABSTRACT Active partition systems and postsegregational killing (PSK) systems are present together in naturally occurring low-copy-number plasmids. Theory suggests that PSK may act as the ultimate determinant of plasmid retention, whereas the partition system may minimize the growth penalty to the host, resulting in a near-ideal ...
Brendler T, Reaves L, Austin S.
europepmc +4 more sources
Coordinating plasmid partition with bacterial chromosome segregation. [PDF]
Proc Natl Acad Sci U S AFunnell BE.
europepmc +3 more sources
Frontiers in Microbiology, 2021 The ParABS partitioning system, a main driver of DNA segregation in bacteria, employs two proteins, ParA and ParB, for plasmid partition. The pMF1 plasmid from Myxococcus fulvus 124B02 has a par operon encoding a small acidic protein, ParC, in addition ...
Duohong Sheng +5 more
doaj +1 more source
eLife, 2021 ParABS partition systems, comprising the centromere-like DNA sequence parS, the parS-binding ParB-CTPase, and the nucleoid-binding ParA-ATPase, ensure faithful segregation of bacterial chromosomes and low-copy-number plasmids.
James A Taylor +4 more
doaj +1 more source