Results 31 to 40 of about 65,619 (298)

Studies on identification of menstrual blood stain by fibrin-plate method. I. A study on the incoagulability of menstrual blood [PDF]

, 1962
As the results of present study on plasmin in menstrual blood by means of the Fibrin-Plate Method, a large amount of plasmin as much as dilution of 1: 100 or 1:1,000 of the menstrual blood serum, has been found in a natural form and it is deduced that ...
Shiraishi, Masumi
core   +1 more source

The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans

eLife, 2020
Osteocalcin (OCN) is an osteoblast-derived hormone with pleiotropic physiological functions. Like many peptide hormones, OCN is subjected to post-translational modifications (PTMs) which control its activity.
Omar Al Rifai, Catherine Julien, Julie Lacombe, Denis Faubert, Erandi Lira-Navarrete, Yoshiki Narimatsu, Henrik Clausen, Mathieu Ferron   +7 more
doaj   +1 more source

Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin

Scientific Reports, 2017
Neuroserpin is a serine protease inhibitor that regulates the activity of plasmin and its activators in the neuronal tissues. This study provides novel evidence of regulatory effect of the neuroserpin on plasmin proteolytic activity in the retina in ...
Vivek Gupta, Mehdi Mirzaei, Veer Bala Gupta, Nitin Chitranshi, Yogita Dheer, Roshana Vander Wall, Mojdeh Abbasi, Yuyi You, Roger Chung, Stuart Graham   +9 more
doaj   +1 more source

Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review

TH Open, 2018
Plasmin is the major fibrinolytic protease responsible for dissolving thrombi by cleavage of its primary substrate fibrin. In addition, emerging evidence points to other roles of plasmin: (1) as a back-up for ADAMTS13 in proteolysis of ultra-large von ...
Lisa N. van der Vorm, Jasper A. Remijn, Bas de Laat, Dana Huskens   +3 more
doaj   +1 more source

A novel mechanism controlling the growth of hemostatic thrombi [PDF]

The Ukrainian Biochemical Journal, 2013
Current knowledge of the mechanisms of blood coagulation does not provide an answer to one pivotal question: why is, in contrast to a pathological thrombus, the growth of normal hemostatic clot after blood vessel injury suddenly terminated?
V. K. Lishko, I. S. Yermolenko, N. P. Podolnikova, T. P. Ugarova   +3 more
doaj   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

Characterizing plasmin-induced lag phase and application of PDMS microfluidics to detection of fibrinolytic activity [PDF]

, 2018
Physical trauma is responsible for over six million deaths annually, and of these roughly 40 percent result from acute traumatic coagulopathy (ATC) occurring in the first few hours of incidence. Patients who have developed ATC have significantly improved
Ghani, Naveed
core  

HGF modulates actin cytoskeleton remodeling and contraction in testicular myoid cells [PDF]

, 2015
The presence of the HGF/Met system in the testicular myoid cells was first discovered by our group. However, the physiological role of this pathway remains poorly understood. We previously reported that HGF increases uPA secretion and TGF-β activation in
Angela, Catizone, Caruso, Maria, Galdieri, Michela, Ricci, Giulia, Rita, Canipari, Scheri, Katia Corano, Virginia, Di Paolo   +6 more
core   +1 more source

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

Advanced Healthcare Materials, EarlyView.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer, Arundhati Joshi, Constantin von Kaisenberg, Dorothea Brüggemann, Cornelia Lee‐Thedieck   +4 more
wiley   +1 more source

Identification of Plasminogen in MatrigelTM and Its Activation by Reconstitution of This Basement Membrane Extract

BioTechniques, 1996
MatrigelTM, a basement membrane (BM) extract of the Engelbreth-Holm-Swarm (EHS) sarcoma, used in tumor invasion assays, was found to contain plasminogen.
A.R. Farina, A. Tiberio, A. Tacconelli, L. Cappabianca, A. Gulino, A. Gulino, A.R. Mackay   +6 more
doaj   +1 more source