Results 81 to 90 of about 65,619 (298)

Plasminogen activation in the musculoskeletal acute phase response: Injury, repair, and disease

Research and Practice in Thrombosis and Haemostasis, 2020
The musculoskeletal system is critical for movement and the protection of organs. In addition to abrupt injuries, daily physical demands inflict minor injuries, necessitating a coordinated process of repair referred to as the acute‐phase response (APR ...
Breanne H.Y. Gibson, Matthew T. Duvernay, Stephanie N. Moore‐Lotridge, Matthew J. Flick, Jonathan G. Schoenecker   +4 more
doaj   +1 more source

Advances in Analysis of Milk Proteases Activity at Surfaces and in a Volume by Acoustic Methods

Sensors, 2020
This review is focused on the application of surface and volume-sensitive acoustic methods for the detection of milk proteases such as trypsin and plasmin. While trypsin is an important protein of human milk, plasmin is a protease that plays an important
Mark Dizon, Marek Tatarko, Tibor Hianik
doaj   +1 more source

Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]

, 2012
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Aberer, Werner, Eberl, Wolfgang, Faßhauer, Maria, Kreuz , Wolfhart, Kurnik, Karin, Kühne, Thomas, Magerl, Markus, Martinez Saguer, Inmaculada, Meyer-Olson, Dirk, Späth, Peter J., Staubach-Renz, Petra, Wahn, Volker   +11 more
core   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

A Retrospective Study of Adult and Pediatric D‐Dimer Tests to Identify Opportunities for Improved Utilization

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction D‐dimers are produced by lysis of cross‐linked fibrin. In children, D‐dimer testing is used to evaluate disseminated intravascular coagulation (DIC) and some inflammatory states, but its use is not validated for screening or ruling out suspected venous thromboembolic events (VTE).
Rabab Al Dawood, Hassan Abu Sabah, Natalie Mathews, James Douketis, Catherine Hayward   +4 more
wiley   +1 more source

Efficacy and safety of argatroban combined with plasmin in the treatment of acute cerebral infarction

Zhongguo linchuang yanjiu
Objective To observe the effects of combined application of argatroban and plasmin on the degree of neurological function deficit and neutrophil (NEUT) count in patients with acute cerebral infarction (ACI) and their safety.
HU Tao*, CAO Hong
doaj   +1 more source

Out With the Old, in With the New: Age‐Related D‐Dimer Thresholds

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background A fixed D‐dimer cut‐off threshold of 0.500 μg/mL is used in Blackrock Health Hermitage Clinic (BHHC) and most Haematology laboratories across Ireland, however, international guidelines have evolved over the past decade, and a growing body of evidence supports the use of age‐adjusted D‐dimer thresholds.
Ciara O'Connor, Claire McIntyre, Claire Wynne   +2 more
wiley   +1 more source

Plasmin reduces fibronectin deposition by mesangial cells in a protease-activated receptor-1 independent manner

Biochemistry and Biophysics Reports, 2017
Background: Protease-activated receptor-1 (PAR-1) potentiates diabetic nephropathy (DN) as evident from reduced kidney injury in diabetic PAR-1 deficient mice. Although thrombin is the prototypical PAR-1 agonist, anticoagulant treatment does not limit DN
Maaike Waasdorp, JanWillem Duitman, C. Arnold Spek   +2 more
doaj   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

A Cathepsin B‐Triggered CO‐Releasing Molecule with a Non‐Toxic Metal Core for Targeted Tumor Delivery

Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.
An iron‐based, enzyme‐triggered CO‐releasing molecule (ET‐CORM) is site‐specifically conjugated to the antibody trastuzumab. This novel ET‐CORM‐antibody conjugate releases carbon monoxide upon cleavage by the tumor‐associated protease cathepsin B. The construct enables selective intracellular CO delivery to HER2‐overexpressing and CatB‐expressing cells,
Inga Černauskienė, Eduardo Izquierdo‐García, Sarah Keller, Harley Betts, Kevin Cariou, Vicente Marchán, Gilles Gasser, Gonçalo J. L. Bernardes   +7 more
wiley   +2 more sources