Results 91 to 100 of about 234,694 (355)

Uso de rTPA e aspirina no tratamento de trombose intracardíaca em recém-nascido Combined rTPA and aspirin therapy for intracardiac thrombosis in neonates

open access: yesArquivos Brasileiros de Cardiologia, 2007
Descreve-se o caso de um recém-nascido prematuro de peso muito baixo, gemelar, com trombose intracardíaca. O recém-nascido apresentou quadro compatível com sepse neonatal, sendo submetido a suporte avançado de vida, terapia com antibióticos, nutrição ...
Fernanda Almeida Tardin   +7 more
doaj   +1 more source

Preventing Candida albicans from subverting host plasminogen for invasive infection treatment

open access: yesEmerging Microbes and Infections, 2020
Candida albicans is a common fungal pathogen in humans that colonizes the skin and mucosal surfaces of the majority healthy individuals. How C.
Si-Min Chen   +10 more
doaj   +1 more source

Identification of a novel regulatory mechanism for the disease associated protein, uPAR [PDF]

open access: yes, 2014
Expression quantitative trait loci (eQTLs), as determined through a series of statistical association studies collectively known as genome-wide association (GWA) studies, have provided us with a hypothesis free approach for the investigation into ...
Hall, Ian P.   +2 more
core  

Evaluation of coagulation activation after Rhinovirus infection in patients with asthma and healthy control subjects: an observational study [PDF]

open access: yes, 2014
Background Asthma exacerbations are frequently triggered by rhinovirus infections. Both asthma and respiratory tract infection can activate haemostasis. Therefore we hypothesized that experimental rhinovirus-16 infection and asthmatic airway inflammation
Bel, EHD   +12 more
core   +4 more sources

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

open access: yesAdvanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu   +7 more
wiley   +1 more source

Trial of Amiloride in Type 2 Diabetes With Proteinuria

open access: yesKidney International Reports, 2017
Renal sodium (Na+) retention and extracellular fluid volume expansion are hallmarks of nephrotic syndrome, which occurs even in the absence of activation of hormones that stimulate renal Na+ transporters. Plasmin-dependent activation of the epithelial Na+
Mark L. Unruh   +5 more
doaj   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

open access: yesAdvanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang   +28 more
wiley   +1 more source

Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation [PDF]

open access: yes, 2010
<p><b>Background and Purpose:</b> Mechanisms of early neurologic deterioration after treatment with intravenous, recombinant, tissue-type plasminogen activator (IV rt-PA) include symptomatic intracerebral hemorrhage (SICH) and early ...
Awadh, M.   +5 more
core   +1 more source

Adjunctive Thrombolytics After Successful Endovascular Reperfusion: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesAnnals of Neurology, EarlyView.
Objective The efficacy and safety of intra‐arterial thrombolysis (IAT) as an adjunct to endovascular thrombectomy (EVT) in large vessel occlusion strokes (LVOS) remain uncertain, with recent randomized controlled trials (RCTs) yielding conflicting results.
Mohamed F. Doheim   +20 more
wiley   +1 more source

"Sudden Drop" in Blood Pressure is Associated With Recanalization After Thrombolysis. [PDF]

open access: yes, 2015
We aim to investigate whether the phenomenon of "sudden drop" in blood pressure (BP) within the first 2 hours is associated with vessel recanalization.We retrospectively examined clinical and imaging data from a consecutive series of patients with stroke
Cao, Jin   +4 more
core   +1 more source

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