Results 91 to 100 of about 105,823 (139)

Transcranial Histotripsy Clot and Tissue Ablation for Intracerebral Hemorrhage Evacuation and Other Brain Applications

, 2023
STROKE: Vascular and Interventional Neurology, EarlyView.
Jonathan Sukovich, Zhen Xu, Aditya S. Pandey   +2 more
wiley   +1 more source

Recurrent hypoglycemia exposure increases the risk of platelet activation and thrombosis in insulin‐treated diabetic rats

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Diabetes is a widespread disease associated with long‐term complications. Treatment of diabetes alleviates these complications but cause an increased risk of recurrent hypoglycemia (RH). Hypoglycemia exposure increases the risk of cardiovascular events by an unknown mechanism.
Ashish K. Rehni, Sunjoo Cho, Allen Liu, Jonathan Lo, Stephanie S. Kim, Nathalie Khoury, Miguel A. Perez‐Pinzon, Wenche Jy, Kunjan R. Dave   +8 more
wiley   +1 more source

Proteomic associations with fluctuation and long‐term changes in BMI: A 40‐year follow‐up study

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Introduction While some studies have explored associations between weight change and blood proteins, most have been intervention‐based, offering limited insight into proteomic associations with long‐term weight gain. It remains unclear whether plasma proteins are related to BMI fluctuation over time.
Alvaro Obeso, Gabin Drouard, Teemu Palviainen, Xiaoling Wang, Miina Ollikainen, Karri Silventoinen, Jaakko Kaprio   +6 more
wiley   +1 more source

Lysosomal cysteine proteinases as mediators of inflammation and tumor spread [PDF]

, 1992
Assfalg-Machleidt, Irmgard, Jochum, Marianne, Jänicke, F., Machleidt, W., Schmitt, M.   +4 more
core   +1 more source

Why, how and in whom should we measure levels of lipoprotein(a): A review of the latest evidence and clinical implications

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Lipoprotein(a) [Lp(a)] is a genetically determined, causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Despite robust evidence from epidemiological and genetic studies, Lp(a) remains underrecognised in clinical practice due to challenges in measurement, lack of guideline familiarity ...
Alexander C. Razavi, Harpreet S. Bhatia, Roger S. Blumenthal, Michael D. Shapiro, Anurag Mehta   +4 more
wiley   +1 more source

Inflammation in atherosclerotic cardiovascular disease: From diagnosis to treatment

European Journal of Clinical Investigation, EarlyView.
Inflammation in atherosclerotic cardiovascular disease. Residual inflammatory risk (RIR), defined by high‐sensitive C‐reactive protein (hsCRP) concentration of ≥2 mg/L, represents a strong predictor of future atherosclerotic cardiovascular disease (ASCVD) events. Although increased hsCRP values ≥2 mg/L might be detected in every three out of five ASCVD
Natalie Arnold, Wolfgang Koenig
wiley   +1 more source

Safety and Efficacy of Long‐Term Treatment of Type 1 Plasminogen Deficient Patients With Intravenous Plasminogen Replacement Therapy

Haemophilia, EarlyView.
ABSTRACT Introduction Type 1 plasminogen deficiency (PLGD‐1), or hypoplasminogenaemia, is an ultra‐rare autosomal‐recessive disorder characterised by fibrin‐rich lesions on mucous membranes, often leading to serious complications if left untreated. Prior treatments have shown limited and inconsistent success, but IV PLG concentrate (Ryplazim) offers a ...
Amy D. Shapiro, Heather McDaniel, Robert W. Decker, Charles Nakar, Jeremy Lorber, Neelam Thukral, Joseph M. Parker, Karen Thibaudeau   +7 more
wiley   +1 more source

Unmasking Convergent Inflammatory and Oxidative Pathways in Asthma

Allergy, EarlyView.
Konstantinos Tourlakopoulos, Georgios Mavrovounis, Lamprini Kontopoulou, Spyros Polyzois, Ioannis Pantazopoulos, Paraskevi Kirgou, Zoe Daniil, Konstantinos I. Gourgoulianis, Ourania S. Kotsiou   +8 more
wiley   +1 more source

Current Practice Regarding Bleeding Disorders of Unknown Cause in the Netherlands: A National Survey

Haemophilia, EarlyView.
ABSTRACT Introduction About 40%–70% of persons with a clinically relevant bleeding tendency who are referred to haemostasis experts are classified as having a ‘bleeding disorder of unknown cause’ (BDUC) as no biological entity can be found after extensive laboratory testing.
Caroline M. A. Mussert, Amaury L. L. Monard, Tirsa T. van Duijl, Yvonne M. C. Henskens, Maartje van den Biggelaar, Roger E. G. Schutgens, Saskia E. M. Schols, Karin J. Fijnvandraat, Karina Meijer, Paul L. den Exter, Laurens Nieuwenhuizen, Iris van Moort, Marieke J. H. A. Kruip, Marjon H. Cnossen, Floor C. J. I. Heubel‐Moenen, for the BDUC‐iN study group   +15 more
wiley   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur, Christopher Dowson, Susan M. Bissett, Rachel van de Merwe, John J. Taylor, Philip M. Preshaw, Katrin M. Jaedicke   +6 more
wiley   +1 more source