Activation of Plasminogen by Staphylokinase [PDF]
Nature, 1960 SOME animal plasminogens, which are unaffected by streptokinase alone, are activated by streptokinase and human globulin. Mullertz1 has postulated the existence of a proactivator in human serum. Staphylokinase, without human globulin, activates a wider range of animal plasminogens2 and may, therefore, not require proactivator.
Flora M. Davidson
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Plasminogen activator inhibitors [PDF]
Blood, 1987 Chemicals/CAS: fibrin, 9001-31-4; plasminogen activator inhibitor, 105844-41-5; plasminogen activator, 9039-53-6; Carrier Proteins; Glycoproteins; Plasminogen Activators, EC 3.4.21.-; Plasminogen Inactivators; Protease Inhibitors; protease ...
Sprengers, E.D., Kluft, C.
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Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines [PDF]
Journal of Neuroinflammation, 2019 Background Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants.
Paola Pontecorvi +8 more
doaj +3 more sources
Diagnostic Ultrasound Induced Inertial Cavitation To Non-Invasively Restore Coronary And Microvascular Flow In Acute Myocardial Infarction [PDF]
, 2013 Ultrasound induced cavitation has been explored as a method of dissolving intravascular and microvascular thrombi in acute myocardial infarction. The purpose of this study was to determine the type of cavitation required for success, and whether longer ...
Everbach, E. Carr +11 more
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Involvement of plasminogen activator inhibitor-1 and its related molecules in atrial fibrosis in patients with atrial fibrillation [PDF]
PeerJ, 2021 Atrial fibrillation is the most common form of cardiac arrhythmia. Atrial fibrosis is a significant feature of atrial fibrillation though its mechanism is not well understood.
Qiaoqiao Li +11 more
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Incidence of Hemorrhagic Complications among Patients Treated with Thrombolytic in Erbil City, Iraq [PDF]
Al-Anbar Medical Journal, 2020 Background: Recombinant tissue-type plasminogen activator is an option of treatment for suspected occlusive vascular thrombi and its sequel (transmural myocardial infarction, pulmonary embolism, and ischemic stroke). The most important concern associated
Ahmed F. Hammad +2 more
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Histone deacetylase inhibitor treatment increases coronary t-PA release in a porcine ischemia model. [PDF]
PLoS ONE, 2014 BACKGROUND: The expression of the tissue plasminogen activator gene can be affected by histone deacetylation inhibition and thus appears to be under epigenetic control.
Kristina Svennerholm +6 more
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Clinical and Applied Thrombosis/Hemostasis, 2023 Background Vitamin D deficiency has recently been suggested as an independent risk factor for thrombosis. Notably, vitamin D deficiency is common in pregnant populations, whom already have an increased thrombotic risk.
Matilde Kanstrup Andersen BA +6 more
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Phosphorylation of human plasminogen activators and plasminogen [PDF]
FEBS Letters, 1995 Plasminogen (PG), urokinase‐type plasminogen activator (u‐PA) and tissue‐type PA (t‐PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t‐PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P‐Tyr residues, as ...
BARLATI, Sergio +4 more
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A novel serine protease secreted by medicinal maggots enhances plasminogen activator-induced fibrinolysis. [PDF]
PLoS ONE, 2014 Maggots of the blowfly Lucilia sericata are used for the treatment of chronic wounds. As haemostatic processes play an important role in wound healing, this study focused on the effects of maggot secretions on coagulation and fibrinolysis.
Mariena J A van der Plas +9 more
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