Results 121 to 130 of about 200,214 (356)
Characterization of plasmin, plasminogen and plasminogen activator in goat milk
Plasmin (PL), a serine-proteinase, appears to be the predominant native proteinase in milk and it is mainly associated to casein micelles which represent its substrate (Bastian and Brown, 1996). Plasmin occurs in milk together with its inactive zymogene,
F. Polidori+3 more
doaj +1 more source
Research progress of neurovascular units involved in ischemic stroke
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang+4 more
wiley +1 more source
Studies on Plasminogen Activators. II. A Method for the Separation of Purified Urokinase from Small Samples of Urine. [PDF]
Ulla Hamberg+7 more
openalex +1 more source
This study has elucidated the role of three swine acute diarrhea syndrome coronavirus (SADS‐CoV) accessory proteins in influencing viral pathogenicity and preliminarily explored the host molecular targets and pathways affected by the NS3a, NS7a, and NS7b proteins of SADS‐CoV.
Xiaoling Yan+7 more
wiley +1 more source
Abstract Tranexamic acid (TXA) is used for the treatment and occasionally prevention of postpartum hemorrhage (PPH); however, questions still remain regarding dosing regimen optimization. This study evaluated TXA pharmacokinetic (PK) data from four clinical trials (NCT: 04274335, 03287336, 00872469, and 02797119) conducted in pregnant participants ...
Allison Dunn+12 more
wiley +1 more source
The association of HER2 status with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor 1 (PAI-1) levels raises the question whether uPA/PAI-1 level carries additional clinically relevant prognostic information independently from ...
Dovnik Nina Fokter, Takac Iztok
doaj +1 more source
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado+9 more
wiley +1 more source
Differential effects of tissue plasminogen activator and streptokinase on infarct size and on rate of enzyme release: influence of early infarct related artery patency: The GUSTO Enzyme Substudy [PDF]
Background The recent international GUSTO trial of 41 021 patients with acute myocardial infarction demonstrated improved 90-mm infarct related artery patency as well as reduced mortality in patients treated with an accelerated regimen of tissue ...
Baardman, T.+6 more
core
A personal 360° view of applications of ‘biomimetic’ molecular recognition
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley +1 more source
Plasminogen activator activity in cultures from human tissues. An immunological and histochemical study [PDF]
Maria B. Bernik, Hau C. Kwaan
openalex +1 more source