Results 171 to 180 of about 3,479,441 (357)

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

Hepatology Research, EarlyView.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura, Aya Naiki‐Ito, Xiaochen Kuang, Akihiro Murakami, Masayuki Komura, Takanori Suzuki, Hiroyuki Kato, Yuko Nagayasu, Kentaro Matsuura, Kei Fujiwara, Hiromi Kataoka, Satoru Takahashi   +11 more
wiley   +1 more source

Mechanical Aortic Valve Thrombosis: Treatment With Tissue Plasminogen Activator. [PDF]

JACC Case Rep
Munawar G, Gupta V, Laiq Z, Sleik K.
europepmc   +1 more source

Thrombolytic Therapy for the Treatment of Prosthetic Heart Valve Thrombosis in Pregnancy With Low-Dose, Slow Infusion of Tissue-Type Plasminogen Activator

Circulation, 2013
M. Özkan, B. Çakal, S. Karakoyun, O. Gürsoy, C. Çevik, M. Kalçık, A. Oğuz, S. Gündüz, M. Astarcıoglu, A. Aykan, Z. Bayram, M. Biteker, E. Kaynak, G. Kahveci, N. Duran, M. Yıldız   +15 more
semanticscholar   +1 more source

GluN2D Subunit-Containing NMDA Receptors Control Tissue Plasminogen Activator-Mediated Spatial Memory [PDF]

, 2012
Pauline Obiang, Richard Macrez, Amandine Jullienne, Thomas Bertrand, Flavie Lesept, Carine Ali, Eric Maubert, Denis Vivien, Véronique Agin   +8 more
openalex   +1 more source

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System in Periodontitis: A Case–Control Study

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur, Christopher Dowson, Susan M. Bissett, Rachel van de Merwe, John J. Taylor, Philip M. Preshaw, Katrin M. Jaedicke   +6 more
wiley   +1 more source

Plasminogen activator inhibitor 1 promotes aortic aging-like pathophysiology in humans and mice. [PDF]

J Clin Invest
Khoddam A, Kalousdian A, Eren M, Soberanes S, Decker A, Lux EJ, Zywicki BW, Dinh B, Boztepe B, Cheema BS, Cuda CM, Abdala-Valencia H, Sivakumar A, Miyata T, Wilsbacher LD, Vaughan DE.   +15 more
europepmc   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

Pars plana vitrectomy with tissue plasminogen activator for traumatic submacular hemorrhage. [PDF]

Int J Ophthalmol
Wang WX, Patel KG, Getahun H, Ramamurthy S, Chen H, Narayanan R, Apte RS.   +6 more
europepmc   +1 more source

High resolution analysis of functional determinants on human tissue-type plasminogen activator.

, 1991
William F. Bennett, Nicholas F. Paoni, Bruce A. Keyt, David Botstein, Andrew J. S. Jones, Leonard G. Presta, Florian Μ. Wurm, Mark J. Zoller   +7 more
openalex   +1 more source

Plasminogen Activator Inhibitor 1 Functions as a Urokinase Response Modifier at the Level of Cell Signaling and Thereby Promotes Mcf-7 Cell Growth [PDF]

, 2001
Donna J. Webb, Keena S. Thomas, Steven L. Gonias   +2 more
openalex   +1 more source