Results 261 to 270 of about 3,479,441 (357)

Sustained Expression of Plasminogen Activator Inhibitor-1 in Patients Recovered from COVID-19 Disease. [PDF]

Med Princ Pract
Mayer O, Bílková S, Nezbedová T, Karnosová P, Windrichová J, Hirmerová J, Pazdiora P, Filipovský J.   +7 more
europepmc   +1 more source

Disrupting BMP/TGF‐β Signaling: Modulation of AQP1 and TGFB1 in Human Pulmonary Microvascular Endothelial Cells

Comprehensive Physiology, Volume 15, Issue 6, December 2025.
Evaluation of targeted gene silencing and exogenous BMP9 administration in HPMECs. AQP1 silencing decreased TGFB1, TGFBR1, and BMPR2 expression, while BMP9 administration returned TGFB1 to basal levels. TGFB1 silencing upregulated BMP9, while downregulating BMP10 and BMPR2 expression. BMP9 administration downregulated AQP1 expression.
Chrysi Keskinidou, Nikolaos S. Lotsios, Kostas A. Papavassiliou, Athanasios G. Papavassiliou, Ioanna Dimopoulou, Anastasia Kotanidou, David Langleben, Stylianos E. Orfanos, Alice G. Vassiliou   +8 more
wiley   +1 more source

Soluble Urokinase Plasminogen Activator Receptor (suPAR) Predicts 28-Day and 90-Day Mortality in Emergency Department Patients with Chest Pain, Dyspnoea, or Abdominal Pain. [PDF]

Diagnostics (Basel)
Gavelli F, Giolitti FM, Vidali M, Montersino M, Bertoli M, Molinari L, Baldrighi M, Beltrame M, Sainaghi PP, Bellan M, Patrucco F, Avanzi GC, Castello LM.   +12 more
europepmc   +1 more source

Organ Crosstalk During Injury: Mechanisms of Lung–Kidney Interaction in Critical Illness

Comprehensive Physiology, Volume 15, Issue 6, December 2025.
Crosstalk between the lungs and kidneys may propagate multiorgan injury in critically ill patients. This review examines evidence of crosstalk between the lungs and kidneys after injury, focusing on translational and mechanistic studies. Pathophysiology and animal models of acute kidney injury (AKI) and acute respiratory distress syndrome (ARDS) are ...
Kathryn M. Sullivan, Kathleen D. Liu, Michael A. Matthay   +2 more
wiley   +1 more source

Soluble urokinase plasminogen activator receptor promotes endoplasmic reticulum stress and apoptosis susceptibility through RAGE in sepsis acute kidney injury. [PDF]

Mol Med
Wang B, Wang J, Qi C, Gao C, Wang Y, Zan Y, Tan Y, Wu Z, Jiang J, Suo J, Zhang J, Peng Z.   +11 more
europepmc   +1 more source

Pulmonary Vascular Endothelial Dysfunction Is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model

Comprehensive Physiology, Volume 15, Issue 6, December 2025.
Pulmonary vascular disease in patients with single ventricular heart disease is a significant source of morbidity and mortality. Utilizing an integrated investigative platform that included a novel ovine Glenn model, we demonstrate early pulmonary vascular endothelial dysfunction with the initiation of the nonpulsatile pulmonary blood flow that ...
Jonathan Hyde, Michael A. Smith, Naveen Swami, John H. Hwang, Yenchun Chao, Jason Boehme, Gary W. Raff, Casper Noah Nilsson, Wenhui Gong, Gail H. Deutsch, Eric G. Johnson, Ting Wang, Stephen M. Black, Sanjeev A. Datar, Emin Maltepe, Jeffrey R. Fineman   +15 more
wiley   +1 more source

Cardiac Rupture and Death Following Administration of Recombinant Tissue-Type Plasminogen Activator (rt-PA). [PDF]

Cureus
Saito T, Ishii T, Aoki T, Zenko M, Yanagisawa K, Otsuki Y, Sugiura R, Kondo Y.   +7 more
europepmc   +1 more source

Role of Angiotensin Receptor Blockers on Cardiovascular Protection in Marfan Syndrome: A Literature Review

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Marfan Syndrome (MFS) is a hereditary connective tissue disorder with severe cardiovascular complications, including aortic aneurysms and dissections. Current therapies, such as beta‐blockers, have limitations in preventing disease progression.
Hashim Mohamed Siraj, Sakshi P. Bidkar, Muhammad Hassan, Nivedita Pant, Muhammad Husnain Ahmad, Masab Ali, Onyekachi Emmanuel Anyagwa, Zuha Zafar, Sumbla Fayyaz, Muhammad Irfan   +9 more
wiley   +1 more source

Corrigendum: Urokinase-type plasminogen activator and plasminogen activator inhibitor-1 complex as a serum biomarker for COVID-19

Frontiers in Immunology
Tetiana Yatsenko, Tetiana Yatsenko, Ricardo Rios, Tatiane Nogueira, Yousef Salama, Satoshi Takahashi, Yoko Tabe, Toshio Naito, Kazuhisa Takahashi, Kazuhisa Takahashi, Koichi Hattori, Koichi Hattori, Beate Heissig   +12 more
doaj   +1 more source

Enhancing Thrombolysis Safety in Post-Acute Ischemic Stroke with Tissue Plasminogen Activator-Associated Microparticles. [PDF]

ACS Nano
Spanò R, Portioli C, Geroski T, Felici A, Palange AL, Gawne PJ, Mamberti S, Avancini G, Palomba R, Bonnard T, Moore TL, Del Sette M, Filipovic N, Vivien D, Decuzzi P.   +14 more
europepmc   +1 more source