Results 261 to 270 of about 3,389,488 (311)

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

Plasminogen Activator in Differentiating Mouse Keratinocytes

, 1983
R. Rivkah Isseroff, Norbert E. Fusenig, Daniel B. Rifkin   +2 more
openalex   +1 more source

Liver steatosis is positively associated with plasminogen activator inhibitor-1 in apparently healthy individuals with overweight and obesity: A FibroScan-Based Cross-Sectional study. [PDF]

J Transl Med
Lisco G, Guido D, Cerabino N, Di Chito M, Donvito R, Bonfiglio C, Shahini E, Zappimbulso M, Randazzo C, Barletta D, Stabile D, Ancona A, Coletta S, Pesole PL, Giannelli G, De Pergola G.   +15 more
europepmc   +1 more source

CCN1 Enhances Tumor Immunosuppression through Collagen‐Mediated Chemokine Secretion in Pancreatic Cancer

Advanced Science, Volume 12, Issue 23, June 20, 2025.
CCN1 modulates the tumor microenvironment in pancreatic cancer by promoting collagen‐dependent chemokine production, thereby facilitating immune evasion. Deletion of CCN1 not only suppresses tumor growth but also enhances immune cell infiltration and increases tumor sensitivity to both chemotherapy and immunotherapy.
Hongjie Fan, Huzi Zhao, Lili Gao, Yucheng Dong, Pei Zhang, Pengfei Yu, Yunfei Ji, Zhe‐Sheng Chen, Xinmiao Liang, Yang Chen   +9 more
wiley   +1 more source

Injectable and Sprayable Thermoresponsive Hydrogel with Fouling‐Resistance as an Effective Barrier to Prevent Postoperative Cardiac Adhesions

Advanced Science, Volume 12, Issue 23, June 20, 2025.
Postoperative cardiac adhesions lead to numerous difficulties in reoperation procedures. Here, a thermo‐responsive in situ formed hydrogel is shown to can reliably cover the wounds after a convenient spraying or injection and significantly reduce adhesion formation in primary and recurrent cardiac injury adhesion models.
Kun Shi, Tao Li, Xulin Hu, Wen Chen, Yan Yu, Zhongwu Bei, Liping Yuan, Qi Tong, Jiafeng Liu, Qiang Fan, Yongjun Qian, Zhiyong Qian   +11 more
wiley   +1 more source

Plasma tissue plasminogen activator-inhibitor complex levels in acute myocardial infarction patients: an observational study. [PDF]

BMC Cardiovasc Disord
Feng YF, Su MY, Xu HX, Zhang SZ, Ma YF, Chen HP.   +5 more
europepmc   +1 more source

LC‐MS/MS proteomics identifies plasma proteins related to cognition over 9‐year follow‐up

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION This project identified plasma proteins predictive of cognitive decline across a robust neuropsychological protocol over a 9‐year period. METHODS Vanderbilt Memory and Aging Project participants (n = 336, 73 ± 7 years, 59% male, 87% non‐Hispanic White, 10% Black/African American) underwent blood draw for baseline plasma protein ...
Hailey A. Adegboye, Khiry L. Patterson, Julia Libby, Yunyi Sun, Panpan Zhang, Dandan Liu, W. Hudson Robb, Amalia J. Peterson, Keith R. Cole, Albert B. Arul, Nekesa C. Oliver, Marsalas D. Whitaker, Kimberly R. Pechman, Logan Dumitrescu, Corey J. Bolton, Kaj Blennow, Henrik Zetterberg, Timothy J. Hohman, Renã A. S. Robinson, Angela L. Jefferson   +19 more
wiley   +1 more source

Soluble Urokinase Plasminogen Activator Receptor: A Useful Marker for Predicting Mortality in COVID-19 Patients. [PDF]

Cureus
Sehgal T, Anand A, Vijayabupathy G, Khan M.   +3 more
europepmc   +1 more source

Intravenous Thrombolysis in Patients Taking Direct Oral Anticoagulation Treatment Before Stroke Onset: Results from the Safe Implementations of Treatments in Stroke International Stroke Registry

Annals of Neurology, Volume 97, Issue 6, Page 1205-1214, June 2025.
Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius, Malin Säflund, Maurizio Balestrino, Manuel Cappellari, Delfina Ferrandi, Abdoreza Ghoreishi, André Peeters, Viiu‐Marika Rand, Manuela De Michele, Aleksandras Vilionskis, Andrea Zini, Niaz Ahmed   +11 more
wiley   +1 more source

Tissue plasminogen activator associated pulmonary hemorrhage in patient with ACTA2-associated arteriopathy. [PDF]

J Vasc Surg Cases Innov Tech
Hughes TG, Wurth MA, Sheppard MB.
europepmc   +1 more source