Results 21 to 30 of about 130,177 (190)
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Multi-Label Activity Recognition using Activity-specific Features and Activity Correlations [PDF]
arXiv, 2020 Multi-label activity recognition is designed for recognizing multiple activities that are performed simultaneously or sequentially in each video. Most recent activity recognition networks focus on single-activities, that assume only one activity in each video.
arxiv
arXiv, 2023 While bacterial swarms can exhibit active turbulence in vacant spaces, they naturally inhabit crowded environments. We numerically show that driving disorderly active fluids through porous media enhances Darcy's law. While purely active flows average to zero flux, hybrid active/driven flows display greater drift than pure-driven fluids.
arxiv
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley +1 more source
A multiscale mathematical model of tumour invasive growth [PDF]
arXiv, 2016 Known as one of the hallmarks of cancer [30], cancer cell invasion of human body tissue is a complicated spatio-temporal multiscale process which enables a localised solid tumour to transform into a systemic, metastatic and fatal disease. This process explores and takes advantage of the reciprocal relation that solid tumours establish with the ...
arxiv
A novel activity pattern generation incorporating deep learning for transport demand models [PDF]
arXiv, 2021 Activity generation plays an important role in activity-based demand modelling systems. While machine learning, especially deep learning, has been increasingly used for mode choice and traffic flow prediction, much less research exploiting the advantage of deep learning for activity generation tasks.
arxiv
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
A Heuristic Bayesian Approach to Knowledge Acquisition: Application to Analysis of Tissue-Type Plasminogen Activator [PDF]
arXiv, 2013 This paper describes a heuristic Bayesian method for computing probability distributions from experimental data, based upon the multivariate normal form of the influence diagram. An example illustrates its use in medical technology assessment. This approach facilitates the integration of results from different studies, and permits a medical expert to ...
arxiv
Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Cancer Communications, EarlyView.Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai +6 more
wiley +1 more source
Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots [PDF]
arXiv, 2019 Tissue plasminogen activator (tPA) is the sole approved therapeutic molecule for the treatment of acute ischemic stroke. Yet, only a small percentage of patients could benefit from this life-saving treatment because of medical contraindications and severe side effects, including brain hemorrhage, associated with delayed administration.
arxiv