Results 121 to 130 of about 627 (174)

Inhibition of Mycobacterium tuberculosis-induced signalling by transforming growth factor-β in human mononuclear phagocytes. [PDF]

Scand J Immunol, 2012
Wu M, Aung H, Hirsch CS, Toossi Z.
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Multiple radiations and its effect on biological system - a review on <i>in vitro</i> and <i>in vivo</i> mechanisms. [PDF]

Ann Med
Balasubramanian D, Agraharam G, Girigoswami A, Girigoswami K.   +3 more
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Increased thrombin-activatable fibrinolysis inhibitor and decreased tissue factor pathway inhibitor and thrombomodulin levels in children with hypothyroidism. [PDF]

J Clin Res Pediatr Endocrinol, 2012
Alioğlu B, Kılıç N, Şimşek E, Dallar Y.   +3 more
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Characterization of a novel class of polyphenolic inhibitors of plasminogen activator inhibitor-1. [PDF]

J Biol Chem, 2010
Cale JM, Li SH, Warnock M, Su EJ, North PR, Sanders KL, Puscau MM, Emal CD, Lawrence DA.   +8 more
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Therapeutic potential of an orally effective small molecule inhibitor of plasminogen activator inhibitor for asthma.

Am J Physiol Lung Cell Mol Physiol, 2016
Liu RM, Eldridge S, Watanabe N, Deshane J, Kuo HC, Jiang C, Wang Y, Liu G, Schwiebert L, Miyata T, Thannickal VJ.   +10 more
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Peroxynitrite Inactivates Tissue Plasminogen Activator

Anesthesia & Analgesia, 2004
Tissue plasminogen activator (tPA) has a prominent role in physiological fibrinolysis in vivo. Thrombosis has been associated with clinical scenarios (e.g., atherosclerotic disease) known to involve local decreases in tPA activity with concomitant formation of reactive nitrogen species such as peroxynitrite (OONO(-)), a molecule formed from nitric ...
Vance G, Nielsen, John P, Crow, Fen, Zhou, Dale A, Parks   +3 more
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Inactivation of plasminogen activator inhibitor by oxidants

Biochemistry, 1986
The rapidly acting plasminogen activator inhibitor (PAI) purified from cultured bovine aortic endothelial cells (BAEs) was inactivated during iodination with chloramine T and other oxidizing iodination systems. Inactivation was observed in the absence of iodine, suggesting that the loss of activity resulted from the oxidizing conditions employed. In an
D A, Lawrence, D J, Loskutoff
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Susceptibility of plasminogen activators to suicide inactivation

Thrombosis Research, 1988
Halomethylated derivatives of dihydrocoumarins are efficient enzyme-activated inhibitors ("suicide" substrates) of plasminogen activators. Kinetic analysis indicate that the one-chain and two-chain forms of the human plasminogen activator are inhibited by 3,4-dihydro-3-benzyl-6-chloromethylcoumarin through a mechanism-based inactivation characterized ...
A, Mor, M, Reboud-Ravaux, J P, Mazaleyrat, M, Wakselman   +3 more
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Selective Inactivation of the Plasminogen Contaminant in Thrombin

Nature, 1960
THE contamination of preparations of thrombin and fibrinogen with plasminogen, the precursor of the fibrinolytic enzyme, has always presented great difficulties in the measurement of fibrinolytic activity.
G, MARKUS, C M, AMBRUS
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