Results 71 to 80 of about 384,388 (342)

The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum

PLoS Biology, 2003
Plasmodium falciparum is the causative agent of the most burdensome form of human malaria, affecting 200–300 million individuals per year worldwide. The recently sequenced genome of P. falciparum revealed over 5,400 genes, of which 60% encode proteins of
Zbynek Bozdech, M. Llinás, B. Pulliam, E. Wong, Jingchun Zhu, J. Derisi   +5 more
semanticscholar   +1 more source

Administration of L-citrulline prevents Plasmodium growth by inhibiting/ modulating T-regulatory cells during malaria pathogenesis

Journal of Vector Borne Diseases, 2022
Background & objectives: Malaria affects around 228 million people all over the globe. Malaria causing parasite Plasmodium infection leads to activation of immune responses. The growth of parasite and immune activation requires semi essential amino acids
Vikky Awasthi, Rubika Chauhan, Jyoti Das
doaj   +1 more source

The cytochrome oxidase defect in ISC‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm22

FEBS Letters, EarlyView.
The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff, Dominik Trauth, Weronika Śliwińska, Linda Boss, Roland Lill   +4 more
wiley   +1 more source

Slime mould computes planar shapes [PDF]

, 2011
Computing a polygon defining a set of planar points is a classical problem of modern computational geometry. In laboratory experiments we demonstrate that a concave hull, a connected alpha-shape without holes, of a finite planar set is approximated by ...
Adamatzky, Andrew
core  

Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections

Advanced Healthcare Materials, EarlyView.
Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic, Evangelos Natsaridis, Timon Flathmann, Daiane P. C. Quadros, Nubia Gogniat, Oya Tagit   +5 more
wiley   +1 more source

PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial

npj Vaccines
The receptor-binding domain, region II, of the Plasmodium vivax Duffy binding protein (PvDBPII) binds the Duffy antigen on the reticulocyte surface to mediate invasion.
Francisco J. Martinez, Michael White, Micheline Guillotte-Blisnick, Christèle Huon, Alix Boucharlat, Fabrice Agou, Patrick England, Jean Popovici, Mimi M. Hou, Sarah E. Silk, Jordan R. Barrett, Carolyn M. Nielsen, Jenny M. Reimer, Paushali Mukherjee, Virander S. Chauhan, Angela M. Minassian, Simon J. Draper, Chetan E. Chitnis   +17 more
doaj   +1 more source

Hurdle in taxonomy: A case of malaria parasites and other Haemosporidia

Open Veterinary Science, 2021
A crucial progress in taxonomy matches with the growth of various branches of biological sciences. This validates the taxonomic positions of many organisms.
Mandal Fatik Baran
doaj   +1 more source

Plasmodium knowlesi Malaria in Sabah, Malaysia, 2015–2017: Ongoing Increase in Incidence Despite Near-elimination of the Human-only Plasmodium Species

Clinical Infectious Diseases, 2019
Background Malaysia aims to eliminate malaria by 2020. However, while cases of Plasmodium falciparum and Plasmodium vivax have decreased substantially, the incidence of zoonotic malaria from Plasmodium knowlesi continues to increase, presenting a major ...
Daniel J Cooper, G. Rajahram, T. William, J. Jelip, R. Mohammad, Joseph Benedict, Danshy A Alaza, E. Malacova, T. Yeo, M. Grigg, N. Anstey, Bridget E. Barber   +11 more
semanticscholar   +1 more source

Plasmodium malariae in Bangladesh

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2010
We describe a 32-year-old Bangladeshi male presenting with severe malaria caused by a mono-infection with Plasmodium malariae. Rosetting of infected and uninfected erythrocytes, a putative virulence factor in falciparum malaria, was observed in the blood slide. Severe disease caused by P. malariae is extremely rare.
Naowarat Tanomsing, Wahid Rahman, Kamolrat Silamut, Richard J. Maude, Richard J. Maude, Kesinee Chotivanich, Arjen M. Dondorp, Arjen M. Dondorp, MA Faiz, Amir Hossain   +9 more
openaire   +3 more sources

Plasmodium malariae and Plasmodium ovale – the ‘bashful’ malaria parasites [PDF]

Trends in Parasitology, 2007
Although Plasmodium malariae was first described as an infectious disease of humans by Golgi in 1886 and Plasmodium ovale identified by Stevens in 1922, there are still large gaps in our knowledge of the importance of these infections as causes of malaria in different parts of the world.
Ivo Mueller, Peter A. Zimmerman, John C. Reeder   +2 more
openaire   +3 more sources