Results 71 to 80 of about 310,877 (350)
Plasmodium’s Sticky Fingers [PDF]
Cell, 2005 The life cycle of the malaria parasite (Plasmodium) is remarkably complex. Malaria parasites must engage in highly specific and varied interactions with cell types of both the mammalian host and the mosquito vector. In this issue of Cell, report detailed molecular insights into an intimate interaction between a malaria parasite protein and its host ...
openaire +3 more sources
Pyronaridine for treatment of Plasmodium ovale and Plasmodium malariae infections [PDF]
Antimicrobial Agents and Chemotherapy, 1997 The clinical efficacy of oral pyronaridine was assessed in 22 symptomatic Cameroonian patients infected with Plasmodium ovale or Plasmodium malariae. All patients were cured on or before day 4. In vitro drug assays confirmed the sensitivity of P. ovale and P. malariae isolates to chloroquine and pyronaridine.
Pascal Ringwald +3 more
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B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns
Advanced Science, EarlyView.B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang +16 more
wiley +1 more source
Journal of Experimental Pharmacology, 2023 Fentaw Girmaw, Getachew Ashagrie Department of Pharmacy, College of Health Science, Woldia University, Woldia, EthiopiaCorrespondence: Fentaw Girmaw, Department of Pharmacy, College of Medicine and Health Science, Woldia University, P.O. Box 400, Woldia,
Girmaw F, Ashagrie G
doaj
A small mitochondrial protein present in myzozoans is essential for malaria transmission [PDF]
Open Biology, 2016 Myzozoans (which include dinoflagellates, chromerids and apicomplexans) display notable divergence from their ciliate sister group, including a reduced mitochondrial genome and divergent metabolic processes.
Dennis Klug +3 more
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Biomedical and Biotechnology Research Journal, 2021 Background: Anemia in pregnancy which may be mild, moderate, or severe is a common physiological disorder that can lead to poor pregnancy outcome which may be primary or secondary to problems associated with hepatic, renal, and immune system which may be
Mathew Folaranmi Olaniyan +2 more
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Immunological Reviews, 2019 Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites have the unique capacity to infect and replicate within host erythrocytes.
Anja T. R. Jensen +2 more
semanticscholar +1 more source
Plasmodium malariae and Plasmodium ovale—Prevalent and Relevant [PDF]
The Journal of Infectious DiseasesContains fulltext : 307856.pdf (Publisher’s version ) (Open Access)
Wouter Graumans +5 more
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Cryopreservation of Plasmodium Sporozoites
Pathogens, 2022 Malaria is a deadly disease caused by the parasite, Plasmodium, and impacts the lives of millions of people around the world. Following inoculation into mammalian hosts by infected mosquitoes, the sporozoite stage of Plasmodium undergoes obligate development in the liver before infecting erythrocytes and causing clinical malaria.
Carson Bowers +10 more
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Advanced Science, EarlyView.ACE can modulate the CBL‐mediated K48 ubiquitination degradation of PSAP by altering its glycosylation levels in NP cells. As a result, NP cells secrete PSAP, which interacts with GPR37 on macrophage surfaces, facilitating their polarization toward the M2 phenotype. These M2 macrophages subsequently secrete TGFβ, which exerts feedback effects on the NP
Youfeng Guo +6 more
wiley +1 more source