Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei [PDF]
Scientific Reports, 2017 The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) harbouring the parasite.
Carolina Agop-Nersesian +5 more
semanticscholar +4 more sources
The Pigment of the Malaria Parasite Plasmodium berghei [PDF]
Journal of General Microbiology, 1953 SUMMARY: The pigment of Plasmodium berghei, a recently discovered parasite of a wild rodent, Thamnomys surdaster, in the Belgian Congo, has been isolated from the infected red cells of young rats in which the strain is maintained in the laboratory. It has been shown by chemical and spectroscopical evidence to be haematin.
J. D. Fulton, C. Rimington
openaire +4 more sources
Behaviour of Plasmodium berghei in some Rodents [PDF]
Nature, 1950 Plasmodium berghei Vincke and Lips 1948 is the first plasmodium found infective for rats and mice1. Vincke and Lips isolated this parasite from a wild tree-rat Thamnonys and found that it produced a fatal infection in mice and rats.
Avivah Zuckerman, M. Yoeli, S. Adler
openaire +4 more sources
BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei [PDF]
PLoS Pathogens, 2014 While the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii are thought to primarily depend on glycolysis for ATP synthesis, recent studies have shown that they can fully catabolize glucose in a canonical TCA cycle.
Rebecca D. Oppenheim +11 more
semanticscholar +3 more sources
Extracellular ATP triggers proteolysis and cytosolic Ca2+ rise in
Malaria Journal, 2012 Background Plasmodium has a complex cell biology and it is essential to dissect the cell-signalling pathways underlying its survival within the host. Methods Using the fluorescence resonance energy transfer (FRET) peptide substrate Abz-AIKFFARQ-EDDnp and
Cruz Laura +6 more
doaj +6 more sources
Exit of Plasmodium Sporozoites from Oocysts Is an Active Process That Involves the Circumsporozoite Protein [PDF]
, 2005 Plasmodium sporozoites develop within oocysts residing in the mosquito midgut. Mature sporozoites exit the oocysts, enter the hemolymph, and invade the salivary glands.
Fujioka, Hisashi +2 more
core +13 more sources
P. berghei telomerase subunit TERT is essential for parasite survival [PDF]
, 2014 Telomeres define the ends of chromosomes protecting eukaryotic cells from chromosome instability and eventual cell death. The complex regulation of telomeres involves various proteins including telomerase, which is a specialized ribonucleoprotein ...
Janse, Chris J. +4 more
core +12 more sources
A Plasmodium falciparum host-targeting motif functions in export during blood stage infection of the rodent malarial parasite Plasmodium berghei. [PDF]
PLoS ONE, 2008 Plasmodium falciparum (P. falciparum) secretes hundreds of proteins--including major virulence proteins--into the host erythrocyte. In order to reach the host cytoplasm, most P. falciparum proteins contain an N terminal host-targeting (HT) motif composed
Julia J MacKenzie +4 more
doaj +1 more source
Malacca leaf ethanolic extract (Phyllanthus emblica) as a hepatoprotector of the liver of mice (Mus musculus) infected with Plasmodium berghei [PDF]
Veterinary World, 2020 Background and Aim: Although existing research confirms the antiparasitic effect of the Malacca plant against Plasmodium, its effect on the liver, one of the target organs of Plasmodium has not been investigated.
Nuzul Asmilia +4 more
doaj +1 more source
Sequestration and tissue accumulation of human malaria parasites: can we learn anything from rodent models of malaria? [PDF]
PLoS Pathogens, 2010 The sequestration of Plasmodium falciparum-infected red blood cells (irbcs) in the microvasculature of organs is associated with severe disease; correspondingly, the molecular basis of irbc adherence is an active area of study.
Blandine Franke-Fayard +4 more
doaj +1 more source