Results 21 to 30 of about 17,618 (180)

Expression profiling of Plasmodium berghei HSP70 genes for generation of bright red fluorescent parasites. [PDF]

PLoS ONE, 2013
Live cell imaging of recombinant malarial parasites encoding fluorescent probes provides critical insights into parasite-host interactions and life cycle progression.
Marion Hliscs, Carolin Nahar, Friedrich Frischknecht, Kai Matuschewski   +3 more
doaj   +1 more source

EFEKTIVITAS PEMBERIAN NANOPARTIKEL EKSTRAK DAUN JUWET (Syzygium cumini) SEBAGAI ADJUVANT TERAPI TERHADAP GAMBARANHISTOPATOLOGI PULMO MENCIT (Mus musculus) YANG DIINFEKSI Plasmodium bhergei

Journal of Basic Medical Veterinary, 2020
The purpose of this study was to learn how to use juwet nanoparticle leaf extract (Syzygium cumini) as an adjunct therapy in pulmonary histopathological mice (Mus musculus) supported by Plasmodium berghei.
Zerlinda Dyah Ayu, Lilik Maslachah, Koesnoto Supranianondo, Endang Suprihati, Hani Plumeriastuti, Rahmi Sugihartuti   +5 more
doaj   +1 more source

Altered Lipid Composition of Surfactant and Lung Tissue in Murine Experimental Malaria-Associated Acute Respiratory Distress Syndrome. [PDF]

PLoS ONE, 2015
Malaria-associated acute lung injury (MA-ALI) and its more severe form malaria-associated acute respiratory distress syndrome (MA-ARDS) are common, often fatal complications of severe malaria infections. However, little is known about their pathogenesis.
Diletta Scaccabarozzi, Katrien Deroost, Natacha Lays, Fausta Omodeo Salè, Philippe E Van den Steen, Donatella Taramelli   +5 more
doaj   +1 more source

Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That Is Reversed by Proteasome Inhibition

mBio, 2020
The recent emergence of Plasmodium falciparum parasite resistance to the first line antimalarial drug artemisinin is of particular concern. Artemisinin resistance is primarily driven by mutations in the P.
Nelson V. Simwela, Barbara H. Stokes, Dana Aghabi, Matt Bogyo, David A. Fidock, Andrew P. Waters   +5 more
doaj   +1 more source

A member of the tryptophan-rich protein family is required for efficient sequestration of Plasmodium berghei schizonts.

PLoS Pathogens, 2022
Protein export and host membrane remodeling are crucial for multiple Plasmodium species to establish a niche in infected hosts. To better understand the contribution of these processes to successful parasite infection in vivo, we sought to find and ...
Julie-Anne Gabelich, Josephine Grützke, Florian Kirscht, Oliver Popp, Joachim M Matz, Gunnar Dittmar, Melanie Rug, Alyssa Ingmundson   +7 more
doaj   +1 more source

Uji Aktivitas Antimalaria dari Spons Xestospongia sp. Asal Pulau Yapen secara In Vivo

Jurnal Kelautan Tropis, 2021
It is generally admitted that marine sponge has rich of secondary metabolite as alkaloids, peptides and terpene. Those various compounds can be used for antimalarial drug.  This study aims to evaluate the in vivo antimalarial activity and to characterize
Murtihapsari Murtihapsari, Mathelda K. Roreng, Apriani Parubak, Alif Rahman   +3 more
doaj   +1 more source

Extract of Morinda lucida leaf rescues hypoglycaemic and dyslipidaemic conditions in Plasmodium berghei-infected mice [PDF]

Bulletin of Natural Sciences Research, 2022
Increasing drug resistance is a great threat to malaria control. Therefore, a continuous investigation into alternative therapy to mitigate malaria-associated damages is important.
Abdulkareem Adam Olaitan, Babamale Abdulkareem Olarewaju, Anifowoshe Abass Toba, Opeyemi Olufunke Adenike Opeyemi Olufunke Adenike, Oloriegbe Nusirat, Adamolekun Comfort, Adetula Samson, Ala Adeola Adefoluke   +7 more
doaj   +1 more source

Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase

Malaria Journal, 2017
Background Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for the growth of Plasmodium parasites ...
Mamoru Niikura, Keisuke Komatsuya, Shin-Ichi Inoue, Risa Matsuda, Hiroko Asahi, Daniel Ken Inaoka, Kiyoshi Kita, Fumie Kobayashi   +7 more
doaj   +1 more source

Rapid and Specific Action of Methylene Blue against Plasmodium Transmission Stages

Pharmaceutics, 2022
Methylene blue (MB) is the oldest synthetic anti-infective. Its high potency against asexual and sexual stages of malaria parasites is well documented.
Nathanaël Saison, Jean-François Franetich, Yudi T. Pinilla, Anton Hoffmann, Stravensky T. Boussougou-Sambe, Barclaye Ngossanga, Maurel Tefit, Kutub Ashraf, Nadia Amanzougaghene, Shahin Tajeri, Ayola A. Adegnika, Dominique Mazier, Steffen Borrmann   +12 more
doaj   +1 more source

Generation of transgenic rodent malaria parasites by transfection of cell culture-derived merozoites

Malaria Journal, 2017
Background Malaria research is greatly dependent on and has drastically advanced with the possibility of genetically modifying Plasmodium parasites. The commonly used transfection protocol by Janse and colleagues utilizes blood stage-derived Plasmodium ...
Gesine Kaiser, Mariana De Niz, Paul-Christian Burda, Livia Niklaus, Rebecca Limenitakis Stanway, Volker Heussler   +5 more
doaj   +1 more source