Results 31 to 40 of about 124,584 (310)

Transcriptome analysis of Plasmodium berghei during exo-erythrocytic development

Malaria Journal, 2019
The complex life cycle of malaria parasites requires well-orchestrated stage specific gene expression. In the vertebrate host the parasites grow and multiply by schizogony in two different environments: within erythrocytes and within hepatocytes. Whereas
R. Caldelari, S. Dogga, M. Schmid, B. Franke-Fayard, C. Janse, Dominique Soldati-Favre, V. Heussler   +6 more
semanticscholar   +1 more source

Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2

eLife, 2021
HAP2 is a transmembrane gamete fusogen found in multiple eukaryotic kingdoms and is structurally homologous to viral class II fusogens. Studies in Plasmodium have suggested that HAP2 is an attractive target for vaccines that block transmission of malaria.
Juan Feng, Xianchi Dong, Adam DeCosta, Yang Su, Fiona Angrisano, Katarzyna A Sala, Andrew M Blagborough, Chafen Lu, Timothy A Springer   +8 more
doaj   +1 more source

Antimalarial Activity of Kaempferol and Its Combination with Chloroquine in Plasmodium berghei Infection in Mice

Journal of Pathogens, 2018
The search for new antimalarial drugs has become an urgent requirement due to resistance to the available drugs and the lack of an effective vaccine. In this respect, the present study aimed to evaluate the antimalarial activity of kaempferol against ...
Voravuth Somsak, Awatsada Damkaew, Pinanong Onrak   +2 more
semanticscholar   +1 more source

Ethanol Root-extract of Sphenocentrum jollyanum Restored Altered Haematological Markers in Plasmodium berghei-infected Mice

Earthline Journal of Chemical Sciences, 2019
Effect of ethanol root-extract of Sphenocentrum jollyanum on some haematological parameters in Plasmodium berghei-infected mice was carried out using a total of thirty-six albino mice.
E. U. Ekpono, P. M. Aja, U. Ibiam, E. Alum, U. E. Ekpono   +4 more
semanticscholar   +1 more source

Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]

, 2017
Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola, E. O. Dada, I. B. Osho, O. O. Ogundolie   +3 more
core   +1 more source

Killer yeasts exert anti-plasmodial activities against the malaria parasite Plasmodium berghei in the vector mosquito Anopheles stephensi and in mice

Parasites & Vectors, 2019
Wickerhamomyces anomalus is a yeast associated with different insects including mosquitoes, where it is proposed to be involved in symbiotic relationships with hosts. Different symbiotic strains of W.
A. Cappelli, M. Valzano, V. Cecarini, J. Bozic, P. Rossi, Priscilla Mensah, C. Amantini, G. Favia, I. Ricci   +8 more
semanticscholar   +1 more source

EFEKTIVITAS PEMBERIAN NANOPARTIKEL EKSTRAK DAUN JUWET (Syzygium cumini) SEBAGAI ADJUVANT TERAPI TERHADAP GAMBARANHISTOPATOLOGI PULMO MENCIT (Mus musculus) YANG DIINFEKSI Plasmodium bhergei

Journal of Basic Medical Veterinary, 2020
The purpose of this study was to learn how to use juwet nanoparticle leaf extract (Syzygium cumini) as an adjunct therapy in pulmonary histopathological mice (Mus musculus) supported by Plasmodium berghei.
Zerlinda Dyah Ayu, Lilik Maslachah, Koesnoto Supranianondo, Endang Suprihati, Hani Plumeriastuti, Rahmi Sugihartuti   +5 more
doaj   +1 more source

Altered Lipid Composition of Surfactant and Lung Tissue in Murine Experimental Malaria-Associated Acute Respiratory Distress Syndrome. [PDF]

PLoS ONE, 2015
Malaria-associated acute lung injury (MA-ALI) and its more severe form malaria-associated acute respiratory distress syndrome (MA-ARDS) are common, often fatal complications of severe malaria infections. However, little is known about their pathogenesis.
Diletta Scaccabarozzi, Katrien Deroost, Natacha Lays, Fausta Omodeo Salè, Philippe E Van den Steen, Donatella Taramelli   +5 more
doaj   +1 more source

Influence of midgut microbiota in Anopheles stephensi on Plasmodium berghei infections

Malaria Journal, 2018
The native gut microbiota of Anopheles mosquitoes is known to play a key role in the physiological function of its host. Interestingly, this microbiota can also influence the development of Plasmodium in its host mosquitoes.
D. Kalappa, P. A. Subramani, S. K. Basavanna, S. Ghosh, V. Sundaramurthy, Sreehari Uragayala, S. Tiwari, A. Anvikar, N. Valecha   +8 more
semanticscholar   +1 more source

Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That Is Reversed by Proteasome Inhibition

mBio, 2020
The recent emergence of Plasmodium falciparum parasite resistance to the first line antimalarial drug artemisinin is of particular concern. Artemisinin resistance is primarily driven by mutations in the P.
Nelson V. Simwela, Barbara H. Stokes, Dana Aghabi, Matt Bogyo, David A. Fidock, Andrew P. Waters   +5 more
doaj   +1 more source