Results 41 to 50 of about 124,584 (310)
Evidence-Based Complementary and Alternative Medicine, 2019 Malaria is a devastating parasitic disease which caused around 216 million cases and 445,000 deaths worldwide in 2016. This might be attributed to a wide spread of drug resistant parasites.
Gebretsadkan Hintsa +2 more
semanticscholar +1 more source
Life cycle studies of the hexose transporter of Plasmodium species and genetic validation of their essentiality [PDF]
, 2010 A Plasmodium falciparum hexose transporter (PfHT) has previously been shown to be a facilitative glucose and fructose transporter. Its expression in Xenopus laevis oocytes and the use of a glucose analogue inhibitor permitted chemical validation of PfHT ...
Doerig, C +6 more
core +2 more sources
Malaria Journal, 2018 Cerebral malaria and severe anaemia are the most common deadly complications of malaria, and are often associated, both in paediatric and adult patients, with hepatopathy, whose pathogenesis is not well characterized, and sometimes also with acute ...
D. Scaccabarozzi +7 more
semanticscholar +1 more source
Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria [PDF]
, 2015 BACKGROUND Sporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine (CPS-CQ) efficiently induces sterile protection against malaria.
Bijker, Else M +5 more
core +2 more sources
Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase
Malaria Journal, 2017 Background Aspartate, which is converted from oxaloacetate (OAA) by aspartate aminotransferase, is considered an important precursor for purine salvage and pyrimidine de novo biosynthesis, and is thus indispensable for the growth of Plasmodium parasites ...
Mamoru Niikura +7 more
doaj +1 more source
PLoS Pathogens, 2022 Protein export and host membrane remodeling are crucial for multiple Plasmodium species to establish a niche in infected hosts. To better understand the contribution of these processes to successful parasite infection in vivo, we sought to find and ...
Julie-Anne Gabelich +7 more
doaj +1 more source
Uji Aktivitas Antimalaria dari Spons Xestospongia sp. Asal Pulau Yapen secara In Vivo
Jurnal Kelautan Tropis, 2021 It is generally admitted that marine sponge has rich of secondary metabolite as alkaloids, peptides and terpene. Those various compounds can be used for antimalarial drug. This study aims to evaluate the in vivo antimalarial activity and to characterize
Murtihapsari Murtihapsari +3 more
doaj +1 more source
Extract of Morinda lucida leaf rescues hypoglycaemic and dyslipidaemic conditions in Plasmodium berghei-infected mice [PDF]
Bulletin of Natural Sciences Research, 2022 Increasing drug resistance is a great threat to malaria control. Therefore, a continuous investigation into alternative therapy to mitigate malaria-associated damages is important.
Abdulkareem Adam Olaitan +7 more
doaj +1 more source
BMC Genomics, 2017 The clinical symptoms of malaria are caused by the asexual replication of Plasmodium parasites in the blood of the vertebrate host. To spread to new hosts, however, the malaria parasite must differentiate into sexual forms, termed gametocytes, which are ...
L. M. Yeoh +4 more
semanticscholar +1 more source
Review of pyronaridine anti-malarial properties and product characteristics. [PDF]
, 2012 Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J +7 more
core +2 more sources