Results 51 to 60 of about 17,618 (180)

Cellular Hallmarks From Volume Electron Microscopy Reveal Developmental Progression of Plasmodium Ookinetes

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif   +12 more
wiley   +1 more source

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia

open access: yesHaematologica, 2017
Malaria, a major global health challenge worldwide, is accompanied by a severe anemia secondary to hemolysis and increased erythrophagocytosis. Iron is an essential functional component of erythrocyte hemoglobin and its availability is controlled by the ...
Chloé Latour   +8 more
doaj   +1 more source

Exploration and Characterization of the Antimalarial Activity of Pyrimidine‐2,4‐Diamines for which Resistance is Mediated by the ABCI3 Transporter

open access: yesChemMedChem, Volume 21, Issue 1, January 2026.
Investigation of the structure‐activity relationship on W482 (1) with a pyrimidine‐2,4‐diamine scaffold culminated in analog 51 with enhanced anti‐plasmodial activity. Forward genetics and phenotypic examination revealed the ABCI3 transporter protein as a putative resistance mechanism.
Mahta Mansouri   +14 more
wiley   +1 more source

Host–parasite oxidative arms race: who will win?

open access: yesJournal of Avian Biology, Volume 2026, Issue 1, January 2026.
Avian haemosporidian parasites are globally widespread with a broad repertoire of hosts. When infected, the host can either reduce (resistance) and/or limit the severity of parasitaemia (tolerance). Oxidative stress plays a pivotal role in the host's resistance and tolerance, as well as its detrimental endpoints.
Caroline Isaksson   +3 more
wiley   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker   +2 more
wiley   +1 more source

A conserved protein of Babesia microti elicits partial protection against Babesia and Plasmodium infection

open access: yesParasites & Vectors, 2023
Background The protozoan parasite Babesia microti that causes the zoonotic disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle.
Yao Wang   +5 more
doaj   +1 more source

Immune Modulation by Plasmodium yoelii: Insights From Lethal and Non‐Lethal Strains

open access: yesParasite Immunology, Volume 48, Issue 1, January 2026.
ABSTRACT Malaria pathogenesis is driven by intricate host–parasite interactions that determine immune balance and clinical outcome. The Plasmodium yoelii model, particularly its lethal (17XL) and non‐lethal (17XNL) strains, provides a robust framework to investigate these dynamics.
Sharoen Yu Ming Lim
wiley   +1 more source

Cannabis‐Derived Compounds Against Plasmodium sp.: A Systematic Review of Preclinical Studies

open access: yesTropical Medicine &International Health, Volume 31, Issue 1, Page 1-9, January 2026.
ABSTRACT Objective This study aims to evaluate preclinical studies on the effects and toxicity of cannabis‐derived compounds against Plasmodium sp. Methods A literature search was conducted in Web of Science, PubMed, Scopus and LILACS databases until December 2024. Studies that assessed the activity or toxicity of cannabis against Plasmodium sp.
Tácio de Mendonça Lima   +5 more
wiley   +1 more source

Methanol Extract of Ficus trigonata Stem Bark Demonstrated Antiplasmodial Activity in Mice

open access: yesBaghdad Journal of Biochemistry and Applied Biological Sciences
Malaria, caused by Plasmodium parasites, remains a global health concern, with drug resistance complicating control efforts. Plant-derived compounds have emerged as potential antimalarial agents.
Suleiman mahmoud Jada   +2 more
doaj   +1 more source

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