Results 51 to 60 of about 12,584 (163)

In vitro activity and in vivo efficacy of omadacycline against Plasmodium species

Malaria Journal
Background Doxycycline is currently the only tetracycline-class antibiotic recommended for malaria prophylaxis. Omadacycline, a semisynthetic aminomethylcycline approved for treatment of adults with community-acquired bacterial pneumonia and acute ...
Michael S. Madejczyk, Susan E. Leed, Karl Kudyba, Alison Roth, Monica L. Martin, Patricia Lee, Diane Anastasiou, Jessica V. Pierce, Alisa W. Serio, Diana Caridha   +9 more
doaj   +1 more source

Neuroprotective and antimalarial effects of Juglans regia leaf extracts in a murine model of cerebral malaria

Frontiers in Veterinary Science
BackgroundMalaria is a major public health problem caused by the apicomplexan Plasmodium parasite. Cerebral malaria (CM) is the most critical outcome of Plasmodium infection.
Afra Alharbi, Shurug Albasyouni, Esam Al-Shaebi, Saleh Al Quraishy, Rewaida Abdel-Gaber   +4 more
doaj   +1 more source

Multi-system dysregulation in placental malaria contributes to adverse perinatal outcomes in mice

Infection and Immunity
Sequestration of Plasmodium parasites in the placental vasculature contributes to increased morbidity and mortality in pregnant compared to non-pregnant patients in malaria-endemic regions.
Phebe Ekregbesi, Brittany Seibert, Maclaine A. Parish, Yevel Flores-Garcia, Patrick S. Creisher, Joseph P. Hoffmann, Jennifer A. Liu, Cory Brayton, Fidel Zavala, Sabra L. Klein   +9 more
doaj   +1 more source

Plasmodium berghei High-Throughput (PbHiT): a CRISPR-Cas9 System to Study Genes at Scale. [PDF]

Bio Protoc
Jonsdottir TK, Paoletta MS, Henriksson J, Bushell ESC.   +3 more
europepmc   +1 more source

Identification of serine/arginine-rich splicing factor 1-interacting proteins in Plasmodium berghei. [PDF]

Malar J
Niikura M, Koyama Y, Fukuda Y, Kato K, Fukutomi T.   +4 more
europepmc   +1 more source

The Putative E3 Ubiquitin Ligase TEX1 Is Required for Nuclear Biology and Developmental Progression of Plasmodium berghei in the Liver. [PDF]

Cells
Schmid M, Golomingi R, Franke-Fayard B, Caldelari R, Rehmann R, Roques M, Heussler VT.   +6 more
europepmc   +1 more source

Erythrocyte Membrane Protein 3 (EMAP3) Is Exposed on the Surface of the Plasmodium berghei Infected Red Blood Cell. [PDF]

Mol Microbiol
Hernandez SRC, Rashpa R, Jonsdottir TK, Paoletta MS, Ter Beek J, Díaz MR, Krol JMM, Chevalley-Maurel S, Ishizaki T, Berntsson RP, Janse CJ, Franke-Fayard B, Brochet M, Bushell ESC.   +13 more
europepmc   +1 more source

Humanization of Drug Metabolism in the <i>Plasmodium berghei</i> Mouse Model for Antimalarial Drug Discovery. [PDF]

ACS Infect Dis
MacLeod AK, Merino C, Viera-Morilla S, Frame L, Tavendale A, Duncan C, Ferguson L, Pinto EG, Simeons FRC, Gomez-Jimenez V, García AB, Riley J, Shishikura Y, Martínez-Martínez MS, Wolf CR, Read KD.   +15 more
europepmc   +1 more source

Spleen protective role, Antiplasmodial and Antioxidant activity of Polyalthia longifolia in mice infected with Plasmodium berghei parasite. [PDF]

Vet Anim Sci
Onobrudu DA, Okpoghono J, Acha JO, Dunkwu CC, Enyi KC, Onyesom I.   +5 more
europepmc   +1 more source

Luminal acetylation of microtubules is not essential for <i>Plasmodium berghei</i> and <i>Toxoplasma gondii</i> survival. [PDF]

Microb Cell
Kumar T, Röver K, Stortz JF, Binder AM, Spreng B, Konert M, Meissner M, Frischknecht F, Jimenez-Ruiz E.   +8 more
europepmc   +1 more source