Results 51 to 60 of about 17,618 (180)
This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif +12 more
wiley +1 more source
Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia
Malaria, a major global health challenge worldwide, is accompanied by a severe anemia secondary to hemolysis and increased erythrophagocytosis. Iron is an essential functional component of erythrocyte hemoglobin and its availability is controlled by the ...
Chloé Latour +8 more
doaj +1 more source
The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium berghei [PDF]
Ravish Rashpa +4 more
openalex +1 more source
Investigation of the structure‐activity relationship on W482 (1) with a pyrimidine‐2,4‐diamine scaffold culminated in analog 51 with enhanced anti‐plasmodial activity. Forward genetics and phenotypic examination revealed the ABCI3 transporter protein as a putative resistance mechanism.
Mahta Mansouri +14 more
wiley +1 more source
Host–parasite oxidative arms race: who will win?
Avian haemosporidian parasites are globally widespread with a broad repertoire of hosts. When infected, the host can either reduce (resistance) and/or limit the severity of parasitaemia (tolerance). Oxidative stress plays a pivotal role in the host's resistance and tolerance, as well as its detrimental endpoints.
Caroline Isaksson +3 more
wiley +1 more source
Sex in Immune Cells and Parasitic Diseases — A Complex Relationship
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker +2 more
wiley +1 more source
Background The protozoan parasite Babesia microti that causes the zoonotic disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle.
Yao Wang +5 more
doaj +1 more source
Immune Modulation by Plasmodium yoelii: Insights From Lethal and Non‐Lethal Strains
ABSTRACT Malaria pathogenesis is driven by intricate host–parasite interactions that determine immune balance and clinical outcome. The Plasmodium yoelii model, particularly its lethal (17XL) and non‐lethal (17XNL) strains, provides a robust framework to investigate these dynamics.
Sharoen Yu Ming Lim
wiley +1 more source
Cannabis‐Derived Compounds Against Plasmodium sp.: A Systematic Review of Preclinical Studies
ABSTRACT Objective This study aims to evaluate preclinical studies on the effects and toxicity of cannabis‐derived compounds against Plasmodium sp. Methods A literature search was conducted in Web of Science, PubMed, Scopus and LILACS databases until December 2024. Studies that assessed the activity or toxicity of cannabis against Plasmodium sp.
Tácio de Mendonça Lima +5 more
wiley +1 more source
Methanol Extract of Ficus trigonata Stem Bark Demonstrated Antiplasmodial Activity in Mice
Malaria, caused by Plasmodium parasites, remains a global health concern, with drug resistance complicating control efforts. Plant-derived compounds have emerged as potential antimalarial agents.
Suleiman mahmoud Jada +2 more
doaj +1 more source

