Results 61 to 70 of about 107,407 (254)

Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei

open access: yesScientific Reports, 2017
The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) harbouring the parasite.
Carolina Agop-Nersesian   +5 more
semanticscholar   +1 more source

CRISPR/Cas9-Based Knockout of GNAQ Reveals Differences in Host Cell Signaling Necessary for Egress of Apicomplexan Parasites

open access: yesmSphere, 2020
Toxoplasma gondii and members of the genus Plasmodium are obligate intracellular parasites that leave their infected host cell upon a tightly controlled process of egress. Intracellular replication of the parasites occurs within a parasitophorous vacuole,
Paul-Christian Burda   +4 more
doaj   +1 more source

Gambaran Histopatologi Hepar Mencit (Mus musculus Balb/C) yang Diinfeksi dengan Plasmodium berghei

open access: yesJurnal Ilmu Kesehatan Indonesia, 2022
Background: The most common cause of death by malaria in Indonesia is Plasmodium falciparum, which is analogous to Plasmodium berghei, which lives as a parasite in the liver of mice.
Hanifah Putri Dwiridal   +2 more
doaj   +1 more source

Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis

open access: yesScientific Reports, 2015
Gastrointestinal symptoms, such as abdominal pain and diarrhea, are frequently observed in patients with Plasmodium falciparum malaria. However, the correlation between malaria intestinal pathology and intestinal microbiota has not been investigated.
T. Taniguchi   +16 more
semanticscholar   +1 more source

HaloPROTAC3 does not trigger the degradation of the halotagged parasitophorous vacuole membrane protein UIS4 during Plasmodium liver stage development

open access: yesScientific Reports
Targeted protein degradation (TPD) is a novel strategy for developing therapeutics against pathogens. Prior to causing malaria, Plasmodium parasites replicate within hepatocytes as liver stages, surrounded by a parasitophorous vacuole membrane (PVM).
Melanie Lam   +22 more
doaj   +1 more source

Inhibition of Plasmodium berghei Development in Mosquitoes by Effector Proteins Secreted from Asaia sp. Bacteria Using a Novel Native Secretion Signal

open access: yesPLoS ONE, 2015
Novel interventions are needed to prevent the transmission of the Plasmodium parasites that cause malaria. One possible method is to supply mosquitoes with antiplasmodial effector proteins from bacteria by paratransgenesis.
N. Bongio, D. Lampe
semanticscholar   +1 more source

Acute Plasmodium yoelii 17XNL Infection During BCG Vaccination Limits T Cell Responses and Mycobacterial Growth Inhibition

open access: yesImmunology, EarlyView.
Tuberculosis and malaria overlap in many sub‐Saharan African countries where BCG vaccination is routinely administered. The aim of this study was to determine whether the timing of BCG vaccination in relation to a malaria infection has implications for BCG vaccine efficacy.
Emily Tangie   +7 more
wiley   +1 more source

Reproductive indices in malaria infested mice treated with antimalarials, Phyllanthus amarus combined with vitamins

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2018
Malaria disease is caused by the plasmodium organism transmitted into humans by the female anopheles mosquito. The effect of chloroquine, artesunate or Phyllantus amarus alone or combined with vitamins A, B, C or K on male fertility indices has received ...
Matthew Obaineh Ojezele   +2 more
doaj  

The Plasmodium berghei translocon of exported proteins reveals spatiotemporal dynamics of tubular extensions

open access: yesScientific Reports, 2015
The erythrocyte is an extraordinary host cell for intracellular pathogens and requires extensive remodelling to become permissive for infection. Malaria parasites modify their host red blood cells through protein export to acquire nutrients and evade ...
J. M. Matz   +6 more
semanticscholar   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

open access: yesJournal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz   +4 more
wiley   +1 more source

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