Results 81 to 90 of about 107,407 (254)

Cyclical Transmission of Plasmodium berghei in the Laboratory [PDF]

Nature, 1952
CYCLICAL transmission of P. berghei has been successfully carried out under experimental conditions. A batch of laboratory-bred A. quadrimaculatus and A. stephensi fed on February 15 on a hamster infected eight days previously with the Kasapa strain of P. berghei.
W. J. Wall, M. Yoeli
openaire   +3 more sources

Anopheles gambiae Blood Feeding Initiates an Anticipatory Defense Response to Plasmodium berghei

Journal of Innate Immunity, 2014
Mosquitoes have potent innate defense mechanisms that protect them from infection by diverse pathogens. Much remains unknown about how different pathogens are sensed and specific responses triggered.
L. Upton, M. Povelones, G. Christophides
semanticscholar   +1 more source

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

FEBS Open Bio, Volume 15, Issue 5, Page 690-698, May 2025.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques, Edit Ábrahám, Hiromi Muramatsu, Daniel Youssef Bargieri, Norbert Pardi, Zoltán Lipinszki   +5 more
wiley   +1 more source

Neuroimmune Pain and Its Manipulation by Pathogens

Evolutionary Applications, Volume 18, Issue 4, April 2025.
ABSTRACT Recent studies highlight extensive crosstalk that exists between sensory neurons responsible for pain and the immune system. Cutaneous pain neurons detect harmful microbes, recruit immune cells, and produce anticipatory immunity in nearby tissues. These complementary systems generally protect hosts from infections.
Kevin W. Lozo, Athena Aktipis, Joe Alcock   +2 more
wiley   +1 more source

Contribution of the Ly49E natural killer receptor in the immune response to Plasmodium berghei infection and control of hepatic parasite development. [PDF]

PLoS ONE, 2014
Natural killer (NK) cells have different roles in the host response against Plasmodium-induced malaria depending on the stage of infection. Liver NK cells have a protective role during the initial hepatic stage of infection by production of the TH1-type ...
Jessica Filtjens, Lander Foquet, Sylvie Taveirne, Els Van Ammel, Mandy Vanhees, Aline Van Acker, Tessa Kerre, Tom Taghon, Bart Vandekerckhove, Jean Plum, Philippe E Van den Steen, Georges Leclercq   +11 more
doaj   +1 more source

BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei

PLoS Pathogens, 2014
While the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii are thought to primarily depend on glycolysis for ATP synthesis, recent studies have shown that they can fully catabolize glucose in a canonical TCA cycle.
Rebecca D. Oppenheim, D. Creek, J. MacRae, Katarzyna K. Modrzynska, P. Pino, Julien P. Limenitakis, Valérie Polonais, F. Seeber, M. Barrett, O. Billker, M. McConville, Dominique Soldati-Favre   +11 more
semanticscholar   +1 more source

Potential mechanisms implied in tick infection by arboviruses and their transmission to vertebrate hosts

Integrative Zoology, Volume 20, Issue 2, Page 315-330, March 2025.
We summarize the recent progress in understanding defense mechanisms in specific tissues or sites that are encountered by arboviruses and discuss their possible roles in virus infection or transmission. Abstract Ticks can transmit many pathogens, including arboviruses, to their vertebrate hosts.
Chuanfei YUAN, Qiong XU, Yunjia NING, Qianfeng XIA   +3 more
wiley   +1 more source

Methanol Extract of Ficus trigonata Stem Bark Demonstrated Antiplasmodial Activity in Mice

Baghdad Journal of Biochemistry and Applied Biological Sciences
Malaria, caused by Plasmodium parasites, remains a global health concern, with drug resistance complicating control efforts. Plant-derived compounds have emerged as potential antimalarial agents.
Suleiman mahmoud Jada, Yusuf Umar, Abdullahi Usman Wurochekke   +2 more
doaj   +1 more source

A conserved protein of Babesia microti elicits partial protection against Babesia and Plasmodium infection

Parasites & Vectors, 2023
Background The protozoan parasite Babesia microti that causes the zoonotic disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle.
Yao Wang, Qianqian Zhang, Wanruo Zhang, Junhu Chen, Jianfeng Dai, Xia Zhou   +5 more
doaj   +1 more source

Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions

Immunological Reviews, Volume 330, Issue 1, March 2025.
ABSTRACT Malaria continues to pose a significant burden to global health. Thus, a strong need exists for the development of a diverse panel of intervention strategies and modalities to combat malaria and achieve elimination and eradication goals. Deploying interventions that target bottlenecks in the transmission life cycle of the causative agent of ...
Randy Yoo, Matthijs M. Jore, Jean‐Philippe Julien   +2 more
wiley   +1 more source