Results 81 to 90 of about 296,027 (331)
H2S Is a Potential Universal Reducing Agent for Prx6‐Type Peroxiredoxins
Advanced Science, EarlyView.We report the identification of H2S as reducing agent for Prx6‐type peroxiredoxins. In contrast to common physiological reducing agents of other peroxiredoxins, HS− is small enough to access the active site of oxidized Prx6‐type enzymes in the fully‐folded protein conformation.
Lukas Lang +3 more
wiley +1 more source
A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern [PDF]
, 2003 The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors.
Sue A. Kyes +51 more
core +1 more source
Submicroscopic placental infection by non-falciparum Plasmodium spp. [PDF]
PLoS Neglected Tropical Diseases, 2018 Among the Plasmodium species that infect humans, adverse effects of P. falciparum and P. vivax have been extensively studied and reported with respect to poor outcomes particularly in first time mothers and in pregnant women living in areas with unstable
Justin Y A Doritchamou +6 more
doaj +1 more source
Nature Communications, 2018 Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for Plasmodium vivax and P.
Alison Roth +26 more
semanticscholar +1 more source
Definitions, 2020 A malária é uma doença ainda muito comum. Em 2002, segundo o relatório da OMS havia cerca de 207 milhões de casos, sendo que apenas naquele ano ocorreram 627 mil mortes.
J. Fernandes, Lucas Nishida
semanticscholar +1 more source
Advanced Science, EarlyView.This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif +12 more
wiley +1 more source
Detection of persistent Plasmodium spp. infections in Ugandan children after artemether-lumefantrine treatment [PDF]
, 2014 During a longitudinal study investigating the dynamics of malaria in Ugandan lakeshore communities, a consistently high malaria prevalence was observed in young children despite regular treatment.
AARON ATUHAIRE +13 more
core +5 more sources
Protection against Plasmodium falciparum malaria by PfSPZ Vaccine.
JCI Insight, 2017 BACKGROUND: A radiation-attenuated Plasmodium falciparum (Pf) sporozoite (SPZ) malaria vaccine, PfSPZ Vaccine, protected 6 of 6 subjects (100%) against homologous Pf (same strain as in the vaccine) controlled human malaria infection (CHMI) 3 weeks after ...
J. Epstein +46 more
semanticscholar +1 more source
Advanced Science, EarlyView.Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang +17 more
wiley +1 more source
Rocaglates as dual-targeting agents for experimental cerebral malaria [PDF]
, 2018 Cerebral malaria (CM) is a severe and rapidly progressing complication of infection by Plasmodium parasites that is associated with high rates of mortality and morbidity.
Ayi, Kodjo +12 more
core +1 more source