Different Life Cycle Stages of Plasmodium falciparum Induce Contrasting Responses in Dendritic Cells [PDF]
Frontiers in Immunology, 2019 Dendritic cells are key linkers of innate and adaptive immunity. Efficient dendritic cell activation is central to the acquisition of immunity and the efficacy of vaccines. Understanding how dendritic cells are affected by Plasmodium falciparum blood-stage parasites will help to understand how immunity is acquired and maintained, and how vaccine ...
Xi Zen Yap +5 more
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Malaria Diagnosis and the Plasmodium Life Cycle: the BFO Perspective [PDF]
, 2009 Definitive diagnosis of malaria requires the demonstration through laboratory tests of the presence within the patient of malaria parasites or their components.
Werner Ceusters, Barry Smith
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Same, same but different: Exploring Plasmodium cell division during liver stage development
PLoS Pathogens, 2023 Plasmodium parasites have a complex life cycle alternating between a mosquito and a vertebrate host. Following the bite of an Anopheles female mosquito, Plasmodium sporozoites are transmitted from the skin to the liver; their first place of replication ...
Magali Roques +3 more
doaj +2 more sources
A constitutive pan‐hexose permease for thePlasmodiumlife cycle and transgenic models for screening of antimalarial sugar analogs [PDF]
The FASEB Journal, 2010 Martin Blume +7 more
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Protein kinase 9 is not required for completion of the Plasmodium berghei life cycle.
Microbiological Research, 2022 Protein kinases uniquely expressed in Plasmodium represent attractive drug targets. Previous studies have reported that Plasmodium falciparum Protein kinase 9 (Pk9) phosphorylates regulatory serine 106 of the ubiquitin-conjugating enzyme (Ubc13) thereby negatively regulating its activity.
S. Narwal +3 more
semanticscholar +3 more sources
Microorganisms, 2023 Malaria, caused by Plasmodium protozoal parasites, remains a leading cause of morbidity and mortality. The Plasmodium parasite has a complex life cycle, with asexual and sexual forms in humans and Anopheles mosquitoes.
Masafumi Yoshinaga +6 more
doaj +1 more source
Conserved RNA Binding Activity of Phosphatidyl Inositol 5-Phosphate 4-Kinase (PIP4K2A)
Frontiers in Molecular Biosciences, 2021 Plasmodium falciparum is a causative agent for malaria and has a complex life cycle in human and mosquito hosts. During its life cycle, the malarial parasite Plasmodium goes through different asexual and sexual stages, in humans and mosquitoes ...
Jatin Behari +12 more
doaj +1 more source
Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle [PDF]
Genome Research, 2004 To investigate the role of post-transcriptional controls in the regulation of protein expression for the malaria parasite, Plasmodium falciparum, we have compared mRNA transcript and protein abundance levels for seven different stages of the parasite life cycle. A moderately high positive relationship between mRNA and protein abundance was observed for
Karine G. Le Roch +11 more
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An epithelial serine protease, AgESP, is required for Plasmodium invasion in the mosquito Anopheles gambiae. [PDF]
PLoS ONE, 2012 Plasmodium parasites need to cross the midgut and salivary gland epithelia to complete their life cycle in the mosquito. However, our understanding of the molecular mechanism and the mosquito genes that participate in this process is still very limited ...
Janneth Rodrigues +6 more
doaj +1 more source
Activation of the hypnozoite: a part of Plasmodium vivax life cycle and survival [PDF]
Malaria Journal, 2011 Plasmodium vivax is the most widespread malaria parasite. It has a dormant stage in the human liver, which makes it difficult to eradicate. It is proposed that a relapse of vivax malaria, besides being genetically determined by the specific strain, is induced by the bites of uninfected vectors.The dormant stage maximizes the possibility for the ...
Huldén Larry, Hulden Lena
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