Results 221 to 230 of about 433,927 (377)

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

Platelet Activating Factor Receptor and Intercellular Adhesion Molecule-1 Expression Increases in the Small Airway Epithelium and Parenchyma of Patients with Idiopathic Pulmonary Fibrosis: Implications for Microbial Pathogenesis. [PDF]

J Clin Med
Shahzad AM, Lu W, Dey S, Bhattarai P, Gaikwad AV, Jaffar J, Westall G, Sutherland D, Singhera GK, Hackett TL, Eapen MS, Sohal SS.   +11 more
europepmc   +1 more source

Endothelial platelet‐derived growth factor‐mediated activation of smooth muscle platelet‐derived growth factor receptors in pulmonary arterial hypertension

, 2020
Kang Wu, Haiyang Tang, Ruizhu Lin, Shane G. Carr, Ziyi Wang, Aleksandra Babicheva, Ramon J. Ayon, Pritesh Jain, Mingmei Xiong, Marisela Rodriguez, Shamin Rahimi, Francesca Balistrieri, Shayan Rahimi, Daniela Valdez‐Jasso, Tatum S. Simonson, Ankit A. Desai, Joe G. N. Garcia, Yuyang Lei, Patricia A. Thistlethwaite, Jian Wang, Ayako Makino, Jason X.‐J. Yuan   +21 more
openalex   +1 more source

Platelet activating factor receptor (PTAFR; PAFR) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Lipoteichoic Acid-Induced Lung Inflammation Depends on TLR2 and the Concerted Action of TLR4 and the Platelet-Activating Factor Receptor

Journal of Immunology, 2008
S. Knapp, S. von Aulock, M. Leendertse, I. Haslinger, C. Draing, D. Golenbock, T. van der Poll   +6 more
semanticscholar   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Erratum: Nuclear localization of platelet-activating factor receptor controls retinal neovascularization. [PDF]

Cell Discov, 2016
Bhosle VK, Rivera JC, Zhou TE, Omri S, Sanchez M, Hamel D, Zhu T, Rouget R, Rabea AA, Hou X, Lahaie I, Ribeiro-da-Silva A, Chemtob S.   +12 more
europepmc   +1 more source

Platelet activating factor receptor (PTAFR; PAFR) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Enhanced platelet activating factor receptor (PAFR) expression in smoker airways

, 2011
Sukhwinder Singh Sohal, Ian Mudway, Stewen Weston, Jonathan Grigg, E. Haydn Walters   +4 more
openalex