Results 241 to 250 of about 158,362 (293)

Gut-Brain Axis Dysregulation in Inflammatory Bowel Disease: Implications for Coagulation Abnormalities and Extraintestinal Manifestations. [PDF]

Int J Gen Med
Lu P, Liu M, Zhang L, Fan JJ, Han G, Hou B, Meng Y, Wang L, Sun Y.   +8 more
europepmc   +1 more source

Autoimmune heparin-induced thrombocytopenia following cardiac surgery. [PDF]

BMJ Case Rep
St Bernard R, Nazy I, Warkentin TE.
europepmc   +1 more source

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Platelet-activating factor receptor

Prostaglandins & Other Lipid Mediators, 2002
Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediator. Although PAF was named for its potential to induce platelet aggregation, intense investigations have elucidated potent biological actions of PAF in a broad range of cell types and tissues.
Zen-ichiro, Honda, Satoshi, Ishii, Takao, Shimizu   +2 more
openaire   +5 more sources

Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice

Progress in Lipid Research, 2000
Platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) is a biologically active phospholipid mediator. Although PAF was initially recognized for its potential to induce platelet aggregation and secretion, intense investigations have elucidated potent biological actions of PAF in a broad range of cell types and tissues, many of
S, Ishii, T, Shimizu
openaire   +4 more sources

Platelet activating factor receptor

Trends in Pharmacological Sciences, 1996
The human platelet-activating factor receptor gene exists as a single copy on chromosome 1. Two 5'-noncoding exons (Exon 1 and 2) has distinct transcription initiation sites and promoters. These exons are alternatively spliced to a common splice acceptor site on exon 3 that contains a total coding regions.
T, Shimizu, H, Mutoh, S, Kato
  +5 more sources

Platelet Activating Factor Receptors

2003
Platelet activating factor (PAF) is a potent pro-inflammatory lipid mediator. Its effects are mediated through cell surface G protein-coupled receptors (GPCRs) that are distributed on numerous cells notably on endothelium [1]. An intracrine mode of action for PAF is proposed based on evidence for intracellular PAF binding sites [2] and retention of ...
A Marilise, Marrache, Fernand, Gobeil, Sylvie G, Bernier, Jana, Stankova, Marek, Rola-Pleszczynski, Sanaa, Choufani, Ghassan, Bkaily, Annie, Bourdeau, Martin G, Sirois, Alejandro, Vazquez-Tello, L, Fan, Jean-Sebastien, Joyal, Janos G, Filep, Daya R, Varma, Alfredo, Ribeiro-Da-silva, Sylvain, Chemtob   +15 more
openaire   +2 more sources

Binding of carbamyl-platelet-activating factor to the raji lymphoblast platelet-activating factor receptor

International Journal of Immunopharmacology, 1992
Carbamyl-platelet-activating factor (1-hexadecyl-2-N-methylcarbamyl-glycero-3-phosphocholine; CPAF) is an analog of platelet-activating factor (PAF) containing an N-methylcarbamyl moiety at the sn-2 position. CPAF was tested for effects on the Raji lymphoblast PAF receptor.
J B, Travers, Q, Li, H, Sprecher, R H, Fertel   +3 more
openaire   +2 more sources

Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils

European Journal of Pharmacology: Molecular Pharmacology, 1994
We investigated the effects of the platelet activating factor (PAF) receptor antagonists, SM-12502 ((+)-cis-3,5-dimethyl-2-(pyridyl)- thiazolidin-4-one hydrochloride), WEB-2086 (3-(4-(2-chlorphenyl)-9-methyl-6H-thieno(3,2-f)-(1,2,4)triazolo(4, 3- a)(1,4)diazepin-2-yl)-1-(4-morpholinyl)-1-propanone) and RP-48740 (3-(3-pyridyl)-1H,3H-pyrrolo[1,2-c ...
H, Koike, N, Imanishi, Y, Natsume, S, Morooka   +3 more
openaire   +2 more sources