Results 21 to 30 of about 5,437,630 (278)

Platelet-activating factor receptor plays a role in lung injury and death caused by influenza A in mice [PDF]

, 2010
Influenza A virus causes annual epidemics which affect millions of people worldwide. A recent Influenza pandemic brought new awareness over the health impact of the disease.
Sousa, Lirlandia P., Garcia, Cristina C., Remo C Russo, Salgado, Ana Paula C., Geovanni D. Cassali, Mauro M. Teixeira, Tavares, L.P., Polidoro, Rafael B., Caio T Fagundes, Luciana P Tavares, Tavares, Luciana P., Machado, A.V., Salgado, Ana Paula Carneiro, Rodrigo Guabiraba, Garcia, C.C., Russo, R.C., Cristiana C Garcia, Guabiraba Brito, R., Remo C. Russo, Alexandre V Machado, Machado, Alexandre Vieira, Polidoro, Rafael Barbosa, Caio T. Fagundes, Cassali, Geovanni D., Teixeira, Mauro Martins, Cassali, Geovanni Dantas, Mauro M Teixeira, Lirlândia P. Sousa, Fagundes, C.T., Salgado, A.P.C., Ana Paula C. Salgado, Cassali, G.D., Garcia, Cristiana Couto, Russo, Remo de Castro, Russo, Remo C., Rafael B. Polidoro, Sousa, L.P., Teixeira, M.M., Ana Paula C Salgado, Alexandre V. Machado, Rafael B Polidoro, Machado, Alexandre V., Fagundes, Caio T., Guabiraba, Rodrigo, Cristiana C. Garcia, Polidoro, R.B., Lirlândia P Sousa, Sousa, Lirlândia Pires de, Geovanni D Cassali, Luciana P. Tavares, Teixeira, Mauro M., Salgado, Ana Paula C, Tavares, Luciana P, Machado, Alexandre V, Polidoro, Rafael B, Cassali, Geovanni D, Teixeira, Mauro M, Sousa, Lirlândia P, Garcia, Cristiana C, Russo, Remo C, Fagundes, Caio T   +60 more
core   +2 more sources

Lipopolysaccharide induces nitric oxide synthase expression and platelet-activating factor increases nitric oxide production in human fetal membranes in culture [PDF]

, 2004
Platelet-activating factor and nitric oxide may be involved in the initiation of human labour as inflammatory mediators. The aim of this study was to test whether platelet-activating factor and lipopolysaccharide were able to induce nitric oxide synthase
Damian J Murphy, Dunmore, Simon J., Murphy Damian J, Carson Ray J, Rodrigo, Nalinda, Seyffarth Gunter, Nelson, Paul N., Dunmore Simon J, Simon J Dunmore, Nalinda Rodrigo, Carson, Ray J., Seyffarth, Gunther, Rodrigo Nalinda, Paul N Nelson, Murphy, Damian J., Nelson Paul N, Gunter Seyffarth, Ray J Carson   +17 more
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Design, Synthesis and Anti-Platelet Aggregation Activity Study of Ginkgolide-1,2,3-triazole Derivatives

Molecules, 2019
Ginkgolides are the major active component of Ginkgo biloba for inhibition of platelet activating factor receptor. An azide-alkyne Huisgen cycloaddition reaction was used to introduce a triazole nucleus into the target ginkgolide molecules.
Jian Cui, Le’An Hu, Wei Shi, Guozhen Cui, Xumu Zhang, Qing-Wen Zhang   +5 more
doaj   +1 more source

Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation [PDF]

, 2005
Oxidation of low-density lipoprotein (LDL) generates proinflammatory and prothrombotic mediators that may play a crucial role in cardiovascular and inflammatory diseases.
Siedler, F., Sellmayer, Alois, Gopfert, M. S., Siess, W.   +3 more
core   +1 more source

Platelet adhesion in atherogenesis [PDF]

, 2010
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyPlatelets are known to play a key role in acute coronary events, such as myocardial infarction, associated with advanced
Watkins, Jennifer
core   +3 more sources

The role of platelet-derived growth factor in radiation injury to the lower urinary tract [PDF]

, 2011
MD ResApproximately half of all patients diagnosed with cancer will receive radiotherapy as a part of the management of their tumours. Radiotherapy allows organ sparing treatment but it is associated with a number of acute and late unwanted effects ...
Sheaff, Michael
core   +4 more sources

To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolase

Journal of Lipid Research, 2014
Mounting ambiguity persists around the functional role of the plasma form of platelet-activating factor acetylhydrolase (PAF-AH). Because PAF-AH hydrolyzes PAF and related oxidized phospholipids, it is widely accepted as an anti-inflammatory enzyme.
Gopal Kedihitlu Marathe, Chaitanya Pandit, Chikkamenahalli Lakshminarayana Lakshmikanth, Vyala Hanumanthareddy Chaithra, Shancy Petsel Jacob, Cletus Joseph Michael D'Souza   +5 more
doaj   +1 more source

A Novel Platelet-Activating Factor Receptor Antagonist Inhibits Choroidal Neovascularization and Subretinal Fibrosis. [PDF]

PLoS ONE, 2013
Choroidal neovascularization (CNV) is a critical pathogenesis in age-related macular degeneration (AMD), the most common cause of blindness in developed countries.
Han Zhang, Yang Yang, Atsunobu Takeda, Takeru Yoshimura, Yuji Oshima, Koh-Hei Sonoda, Tatsuro Ishibashi   +6 more
doaj   +1 more source

Anti-platelet therapy: ADP receptor antagonists. [PDF]

, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD, Stan Heptinstall, Yanushi Dullewe Wijeyeratne   +3 more
core   +1 more source

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Erl, Wolfgang, Weber, Christian, Kim S. C. Weber, Weber, Kim S.C., Weber, Peter C., Wolfgang Erl, Peter C. Weber, Christian Weber   +7 more
core   +1 more source