Results 141 to 150 of about 237,113 (353)

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

Advanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal, Elizabeth M. Byrnes, Sanika Pandit, Halle J. Cantor, Muskan Aslam, Stacy Ban, Megan Palmisano, Rosemary Bayless, Ashley C. Brown, Michael Daniele   +9 more
wiley   +1 more source

Diagnostic and prognostic value of platelet aggregation rate in sepsis-associated coagulation disorders

Zhongguo shuxue zazhi
[Objective] To analyze the diagnostic and prognostic value of platelet aggregation rate in sepsis-related coagulation disorders. [Methods] A total of 238 patients with sepsis were enrolled from Xinjiang Uygur Autonomous Region People's Hospital between ...
WANG Rubin, MA Xiaojie, LI Fei, CHEN Wei
doaj   +1 more source

Multicenter evaluation of light transmission platelet aggregation reagents: communication from the ISTH SSC Subcommittee on Platelet Physiology [PDF]

, 2023
Marie‐Christine Alessi, Carmen Coxon, Manal Ibrahim‐Kosta, Monica Bacci, Sophie Voisin, José Rivera, Andreas Greinacher, Johannes Raster, Fabio M. Pulcinelli, Katrien Devreese, François Mullier, Áine McCormick, Juan Pablo Frontroth, Claire Pouplard, Ulrich J. Sachs, Isabelle Diaz, Nuria Bermejo, Marina Camera, Pierre Fontana, Anne Bauters, Alain Stépanian, Maria Rita Cozzi, Anastasia N. Sveshnikova, Dorothée Faille, Wendy Hollon, Meera Chitlur, Alessandra Casonato, Dominique Lasne, Cécile Lavenu‐Bombled, Mathieu Fiore, Bello Hamidou, Marie‐Françoise Hurtaud‐Roux, Paul Saultier, Louisa Goumidi, Paolo Gresele, Marie Lordkipanidzé   +35 more
openalex   +1 more source

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Smoking-induced long-lasting modifications of human platelet serotonin catabolism through a MAO epigenetic regulation [PDF]

, 2008
Postulating that serotonin, secreted from smoking-activated platelets, could be involved in smoking-induced vascular modifications, we studied 115 men distributed in smokers (S), former smokers (FS) and never smokers (NS).
Alain Simon, Francine Rendu, Gilles Chironi, Jacques Callebert, Jacques Mallet, Jean-Louis Mé, Jean-Marie Launay, Katell Peoc', Muriel Del Pino   +8 more
core   +1 more source

S47 Pneumolysin promotes neutrophil: platelet aggregation in vitro [PDF]

, 2016
Jan G. Nel, Chrisna Durandt, AJ Theron, GR Tintinger, Timothy J. Mitchell, Charles Feldman, Ronald Anderson   +6 more
openalex   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Lisinopril effects on platelet activity in patients with arterial hypertension and impaired glucose tolerance

Российский кардиологический журнал, 2008
The study investigated ACE inhibitor lisinopril (Diroton, Gedeon Richter, Hungary) effects on platelet aggregation in patients with arterial hypertension (AH) and impaired glucose tolerance (IGT).
I. N. Medvedev, O. V. Gamolina
doaj  

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source