Results 11 to 20 of about 121,734 (312)
Optimized tool for evaluation of platelet function measured by impedance aggregometry
Platelets, 2021 Platelet aggregation measured by impedance aggregometry is highly dependent on platelet count. We previously developed a tool to interpret impedance aggregometry based on the strong linear correlation between platelet counts and platelet aggregation at ...
Anna Schultz-Lebahn +3 more
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Thrombin-induced platelet aggregation −effect of dabigatran using automated platelet aggregometry−
Platelets, 2020 Dabigatran, a direct oral thrombin inhibitor, has two therapeutic effects: anticoagulation; and antiplatelet activity. In the clinical field, evaluation of the effect of dabigatran on thrombin-induced platelet aggregation is difficult because of fibrin ...
Mie Shimizu +10 more
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Redox Biology, 2022 Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S–S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively. PDI has been
Lu Wang +6 more
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Role of platelet aggregation in metastatic breast cancer patients
Indian Journal of Pathology and Microbiology, 2020 Background and Aims: Breast cancer is the most common female cancer in the world. Although early detection and systematic adjuvant therapy has improved survival, distant metastasis remains the leading cause of breast related mortality.
Tanisha Singla +4 more
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Effect of 3-Day Storage and Temperature on ADP-induced Platelet Aggregation
International Journal of Integrated Health Sciences, 2018 Objective: To observe platelet functions during the 3 days of platelet storage and to evaluate the effect of storage temperature towards platelet aggregation response.
Nanda Ayu Puspita, Suryawati
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Garlic inhibitory effect on platelet activity induced by different agonists
Revista de la Facultad de Ciencias Agrarias, 2021 Platelets are essential elements of human blood. In addition to their normal role, platelets are involved in causing myocardial infarction, stroke and other thrombotic disorders.
Roxana Elizabeth González +3 more
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Aggregation of platelets by collagen [PDF]
Journal of Clinical Investigation, 1968 In studying some of the properties of collagen responsible for the ability to aggregate platelets it was found that thermal treatment at pH 2.5 of acid-soluble human collagen resulted in a sharp reduction in relative viscosity and platelet aggregating activity at about 35 degrees C.
G. D. Wilner +2 more
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EBioMedicine, 2021 Background: Dyslipidemia induces platelet hyperactivation and hyper-aggregation, which are linked to thrombosis. Anthocyanins could inhibit platelet function in vitro and in mice fed high-fat diets with their effects on platelet function in subjects with
Zezhong Tian +13 more
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Platelet aggregation pathway [PDF]
Pharmacogenetics and Genomics, 2011 Platelet activation and coagulation normally do not occur in an intact blood vessel. After blood vessel wall injury, platelet plug formation is initiated by the adherence of the platelets to subendothelial collagen [1,2]. In high shear arterial blood, platelets are first slowed down from their blood flow velocity by interacting with the collagen-bound ...
Russ B. Altman +3 more
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Thrombopoietin and platelet aggregation in patients with stable coronary artery disease
Platelets, 2017 Thrombopoietin (TPO) may facilitate platelet activation and aggregation. However, data on the impact of TPO on platelet aggregation in patients with stable coronary artery disease (CAD) are scarce.
Sanne Bøjet Larsen +5 more
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