Results 21 to 30 of about 232,382 (353)

Role of platelet aggregation in metastatic breast cancer patients

Indian Journal of Pathology and Microbiology, 2020
Background and Aims: Breast cancer is the most common female cancer in the world. Although early detection and systematic adjuvant therapy has improved survival, distant metastasis remains the leading cause of breast related mortality.
Tanisha Singla, Gaurav Singla, Sunil Ranga, Swati Singla, Rashmi Arora   +4 more
doaj   +1 more source

Garlic inhibitory effect on platelet activity induced by different agonists

Revista de la Facultad de Ciencias Agrarias, 2021
Platelets are essential elements of human blood. In addition to their normal role, platelets are involved in causing myocardial infarction, stroke and other thrombotic disorders.
Roxana Elizabeth González, Verónica Carolina Soto, María Mirta Sance, Claudio Rómulo Galmarini   +3 more
doaj   +1 more source

Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3 [PDF]

, 2016
Gram-negative Escherichia coli cause diseases such as sepsis and hemolytic uremic syndrome in which thrombotic disorders can be found. Direct platelet–bacterium interactions might contribute to some of these conditions; however, mechanisms of human ...
Arman, Mònica, Cox, Dermot, Henderson, Ian R., Kerrigan, Steven W., Watson, Callum N., Watson, Steve P.   +5 more
core   +3 more sources

Aggregation of platelets by collagen [PDF]

Journal of Clinical Investigation, 1968
In studying some of the properties of collagen responsible for the ability to aggregate platelets it was found that thermal treatment at pH 2.5 of acid-soluble human collagen resulted in a sharp reduction in relative viscosity and platelet aggregating activity at about 35 degrees C.
G. D. Wilner, Hymie L. Nossel, E. C. LeRoy   +2 more
openaire   +3 more sources

Dose-dependent effects of anthocyanin supplementation on platelet function in subjects with dyslipidemia: A randomized clinical trial

EBioMedicine, 2021
Background: Dyslipidemia induces platelet hyperactivation and hyper-aggregation, which are linked to thrombosis. Anthocyanins could inhibit platelet function in vitro and in mice fed high-fat diets with their effects on platelet function in subjects with
Zezhong Tian, Kongyao Li, Die Fan, Yimin Zhao, Xiaoli Gao, Xilin Ma, Lin Xu, Yilin Shi, Fuli Ya, Jinchao Zou, Ping Wang, Yuheng Mao, Wenhua Ling, Yan Yang   +13 more
doaj   +1 more source

FbsA, a fibrinogen-binding protein from Streptococcus agalactiae, mediates platelet aggregation [PDF]

, 2005
The bacterium Streptococcus agalactiae is an etiologic agent in the pathogenesis of endocarditis in humans. FbsA, a fibrinogen-binding protein produced by this pathogen, is considered an important virulence factor.
Fitzgerald, J Ross, Foster, Timothy J, Pietrocola, Giampiero, Reinscheid, Dieter J, Schubert, Axel, Speziale, Pietro, Torti, Mauro, Visai, Livia   +7 more
core   +1 more source

Platelet aggregation pathway [PDF]

Pharmacogenetics and Genomics, 2011
Platelet activation and coagulation normally do not occur in an intact blood vessel. After blood vessel wall injury, platelet plug formation is initiated by the adherence of the platelets to subendothelial collagen [1,2]. In high shear arterial blood, platelets are first slowed down from their blood flow velocity by interacting with the collagen-bound ...
Russ B. Altman, Katrin Sangkuhl, Teri E. Klein, Alan R. Shuldiner   +3 more
openaire   +3 more sources

Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx-001. [PDF]

, 2018
The platelet inhibitory effects of the Phase 3 anticancer agent and nitric oxide (NO) donor, RRx-001, (1-bromoacetyl-3,3-dinitroazetidine) were examined ex vivo and compared with the diazeniumdiolate NO donor, diethylenetriamine NONOate (DETA-NONOate ...
Bryan Oronsky, Neil Oronsky, Pedro Cabrales, Santoro SA   +3 more
core   +1 more source

Thrombopoietin and platelet aggregation in patients with stable coronary artery disease

Platelets, 2017
Thrombopoietin (TPO) may facilitate platelet activation and aggregation. However, data on the impact of TPO on platelet aggregation in patients with stable coronary artery disease (CAD) are scarce.
Sanne Bøjet Larsen, Erik Lerkevang Grove, Søs Neergaard-Petersen, Morten Würtz, Anne-Mette Hvas, Steen Dalby Kristensen   +5 more
doaj   +1 more source

Platelet aggregation and quality control of platelet concentrates produced in the Amazon Blood Bank

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: The study of platelet aggregation is essential to assess in vitro platelet function by different platelet activation pathways. OBJECTIVE: To assess aggregation and biochemical parameters of random platelet concentrates produced at the ...
Maria José Dantas Coêlho, Taysa de Castro Monteiro, Felicien Gonçalves Vasquez, Kátia Luz Torres Silva, Kleber Sandro Brasil dos Santos, Viviana Maria Araújo de Oliveira, Francimary de Oliveira Cavalcante   +6 more
doaj   +1 more source