Results 21 to 30 of about 121,734 (312)
Platelet aggregation and quality control of platelet concentrates produced in the Amazon Blood Bank
BACKGROUND: The study of platelet aggregation is essential to assess in vitro platelet function by different platelet activation pathways. OBJECTIVE: To assess aggregation and biochemical parameters of random platelet concentrates produced at the ...
Maria José Dantas Coêlho+6 more
doaj +1 more source
Polyamines and platelet aggregation
Abstract High blood concentrations of the naturally occurring polyamines have been reported in leukemia, psoriasis, cystic fibrosis and polycythemia rubra vera. Spermidine and spermine inhibit in vitro plate-let aggregation of platelet rich plasma preparations in which ADP and Ristocetin are the agglutinating agents.
Division of Genetics, Endocrinology and Metabolism Departments of Pediatrics, Biochemistry and Neuroscience University of Florida, Gainesville-Sunland Research Laboratory Gainesville, Florida 32610, U.S.A. ( host institution )+4 more
openaire +4 more sources
Genetic determinants of on-aspirin platelet reactivity: focus on the influence of PEAR1.
BackgroundPlatelet aggregation during aspirin treatment displays considerable inter-individual variability. A genetic etiology likely exists, but it remains unclear to what extent genetic polymorphisms determine platelet aggregation in aspirin-treated ...
Morten Würtz+4 more
doaj +1 more source
Platelet aggregation in healthy women during normal pregnancy - a longitudinal study
Increased platelet activation is involved in obstetric complications such as preeclampsia and intrauterine growth retardation. It is of interest to study platelet aggregation during pregnancy, since increased aggregation theoretically could be a ...
Lennart Rune Fredrik Blomqvist+3 more
doaj +1 more source
Background A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A:E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor treatment.
Maria J. Reimann+9 more
doaj +1 more source
Coronary artery disease (CAD) remains a major cause of mortality and morbidity worldwide. The aggregation of activated platelets on a ruptured atherosclerotic plaque is a critical step in most acute cardiovascular events like myocardial infarction ...
Ali R Keramati+8 more
doaj +1 more source
Effects of electronic cigarette flavorants on human platelet aggregation ex vivo
Because little is known about the effects of individual flavorants in electronic cigarette (e-cig) fluids on human platelet aggregation, we tested for the direct effects of 15 common e-cig flavorants on adenosine diphosphate (ADP)-induced human platelet ...
Andre Richardson+6 more
doaj +1 more source
Human black and white-skinned races exhibited differences in platelet aggregation. However, no similar differences were described on white and black camels.
Abeer Khalid Al-Ghumlas
doaj +1 more source
Augmentation by resveratrol of the inhibitory effect of ethanol on platelet aggregation
Ethanol and resveratrol have been shown to inhibit platelet aggregation. The aim of this study was to determine whether resveratrol has an additional effect on ethanol-induced inhibition of platelet aggregation.
Kazumi Ekawa+2 more
doaj +1 more source
Mucor circinelloides induces platelet aggregation through integrin αIIbβ3 and FcγRIIA
Thrombosis is a hallmark of the fatal fungal infection mucormycosis. Yet, the platelet activation pathway in response to mucormycetes is unknown. In this study we determined the platelet aggregation potential of Mucor circinelloides (M.
Harlene Ghuman+5 more
doaj +1 more source