Results 21 to 30 of about 119,640 (264)

No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan‐induced inhibition of platelet aggregation response

Journal of Veterinary Internal Medicine, 2023
Background A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A:E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor treatment.
Maria J. Reimann, Daniel N. Faisst, Mads Knold, Kathryn M. Meurs, Joshua A. Stern, Signe E. Cremer, Jacob E. Møller, Ingrid Ljungvall, Jens Häggström, Lisbeth H. Olsen   +9 more
doaj   +1 more source

Thrombospondin promotes platelet aggregation [PDF]

Blood, 1988
Abstract Thrombospondin (TSP), isolated from human platelets, promotes aggregation of both nonstimulated platelets and platelets stimulated with thrombin or ADP. The TSP-promoted aggregation is specific since a monoclonal antibody against TSP inhibits the effect of exogenously added TSP and inhibits thrombin-induced platelet aggregation ...
G P, Tuszynski, V L, Rothman, A, Murphy, K, Siegler, K A, Knudsen   +4 more
openaire   +3 more sources

Targeted deep sequencing of the PEAR1 locus for platelet aggregation in European and African American families

Platelets, 2019
Coronary artery disease (CAD) remains a major cause of mortality and morbidity worldwide. The aggregation of activated platelets on a ruptured atherosclerotic plaque is a critical step in most acute cardiovascular events like myocardial infarction ...
Ali R Keramati, Lisa R Yanek, Kruthika Iyer, Margaret A Taub, Ingo Ruczinski, Diane M Becker, Lewis C Becker, Nauder Faraday, Rasika A Mathias   +8 more
doaj   +1 more source

Effects of electronic cigarette flavorants on human platelet aggregation ex vivo

Toxicology Reports, 2022
Because little is known about the effects of individual flavorants in electronic cigarette (e-cig) fluids on human platelet aggregation, we tested for the direct effects of 15 common e-cig flavorants on adenosine diphosphate (ADP)-induced human platelet ...
Andre Richardson, Tatiana Krivokhizhina, Pawel Lorkiewicz, Stanley D’Souza, Aruni Bhatnagar, Sanjay Srivastava, Daniel J. Conklin   +6 more
doaj   +1 more source

Analysis of kinetics of light scattering by cell suspection during aggregation: mathematical modeling of platelet disaggregation

Вісник Харківського національногоуніверситету імені В.Н. Каразіна. Серія: Радіофізика та електроніка, 2021
Background. Molecular mechanisms of platelet aggregation are actively studied by methods of molecular cell biology, biochemistry, applied physics, but the problem of modeling the dynamics of this process remains open.
O. V. Pertsov, V. P. Berest
doaj   +1 more source

Camel platelet aggregation responses and the antiplatelet effect of camel urine: comparison between black and white camels

Heliyon, 2020
Human black and white-skinned races exhibited differences in platelet aggregation. However, no similar differences were described on white and black camels.
Abeer Khalid Al-Ghumlas
doaj   +1 more source

Augmentation by resveratrol of the inhibitory effect of ethanol on platelet aggregation

Platelets, 2023
Ethanol and resveratrol have been shown to inhibit platelet aggregation. The aim of this study was to determine whether resveratrol has an additional effect on ethanol-induced inhibition of platelet aggregation.
Kazumi Ekawa, Mikio Marumo, Ichiro Wakabayashi   +2 more
doaj   +1 more source

Mucor circinelloides induces platelet aggregation through integrin αIIbβ3 and FcγRIIA

Platelets, 2019
Thrombosis is a hallmark of the fatal fungal infection mucormycosis. Yet, the platelet activation pathway in response to mucormycetes is unknown. In this study we determined the platelet aggregation potential of Mucor circinelloides (M.
Harlene Ghuman, Alicia Shepherd-Roberts, Stephanie Watson, Malou Zuidscherwoude, Steve P. Watson, Kerstin Voelz   +5 more
doaj   +1 more source

Effects of pentoxifylline on canine platelet aggregation

Veterinary Medicine and Science, 2021
Background Pentoxifylline can decrease platelet function in humans, but the anti‐platelet effects of pentoxifylline in dogs is unknown. The addition of a luciferin–luciferase reagent during platelet aggregometry can induce a dose‐dependent potentiation ...
John M. Thomason, Todd M. Archer, Robert W. Wills, Andrew J. Mackin   +3 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source