Results 31 to 40 of about 1,089,521 (397)
Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx-001. [PDF]
, 2018 The platelet inhibitory effects of the Phase 3 anticancer agent and nitric oxide (NO) donor, RRx-001, (1-bromoacetyl-3,3-dinitroazetidine) were examined ex vivo and compared with the diazeniumdiolate NO donor, diethylenetriamine NONOate (DETA-NONOate ...
Bryan Oronsky +3 more
core +1 more source
Thrombopoietin and platelet aggregation in patients with stable coronary artery disease
Platelets, 2017 Thrombopoietin (TPO) may facilitate platelet activation and aggregation. However, data on the impact of TPO on platelet aggregation in patients with stable coronary artery disease (CAD) are scarce.
Sanne Bøjet Larsen +5 more
doaj +1 more source
Platelet aggregation and quality control of platelet concentrates produced in the Amazon Blood Bank
Revista Brasileira de Hematologia e Hemoterapia, 2011 BACKGROUND: The study of platelet aggregation is essential to assess in vitro platelet function by different platelet activation pathways. OBJECTIVE: To assess aggregation and biochemical parameters of random platelet concentrates produced at the ...
Maria José Dantas Coêlho +6 more
doaj +1 more source
Genome-wide association study of platelet aggregation in African Americans
BMC Genetics, 2015 We have previously shown that platelet aggregation has higher heritability in African Americans than European Americans. However, a genome-wide association study (GWAS) of platelet aggregation in African Americans has not been reported.
R. Qayyum +9 more
semanticscholar +1 more source
MMP-13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation. [PDF]
, 2018 BACKGROUND: Acute thrombotic syndromes lead to atherosclerotic plaque rupture with subsequent thrombus formation, myocardial infarction and stroke. Following rupture, flowing blood is exposed to plaque components, including collagen, which triggers ...
Farndale, Richard W +6 more
core +4 more sources
Genetic determinants of on-aspirin platelet reactivity: focus on the influence of PEAR1.
PLoS ONE, 2014 BackgroundPlatelet aggregation during aspirin treatment displays considerable inter-individual variability. A genetic etiology likely exists, but it remains unclear to what extent genetic polymorphisms determine platelet aggregation in aspirin-treated ...
Morten Würtz +4 more
doaj +1 more source
Platelet aggregation in healthy women during normal pregnancy - a longitudinal study
Platelets, 2019 Increased platelet activation is involved in obstetric complications such as preeclampsia and intrauterine growth retardation. It is of interest to study platelet aggregation during pregnancy, since increased aggregation theoretically could be a ...
Lennart Rune Fredrik Blomqvist +3 more
doaj +1 more source
The Professional Medical Journal, 2018 The herbal use for medical purposes is increasing world over. Aloe vera is onesuch herb with established anti-inflammatory action. It has great prospect in terms of replacingtraditional NSAIDS due to better side effect profile on gastrointestinal tract but its effect onplatelet aggregation is what needs to be determined.
Sidra Mushtaq +5 more
openaire +4 more sources
Journal of Veterinary Internal Medicine, 2023 Background A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A:E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor treatment.
Maria J. Reimann +9 more
doaj +1 more source
Thrombospondin promotes platelet aggregation [PDF]
Blood, 1988 Abstract Thrombospondin (TSP), isolated from human platelets, promotes aggregation of both nonstimulated platelets and platelets stimulated with thrombin or ADP. The TSP-promoted aggregation is specific since a monoclonal antibody against TSP inhibits the effect of exogenously added TSP and inhibits thrombin-induced platelet aggregation ...
G P, Tuszynski +4 more
openaire +3 more sources