Effect of Oral Anti-platelet Regimens on Platelet Aggregation using Chronolog Light Transmittance Aggregometry in Coronary Heart Disease Patients: An Observational Study [PDF]
Journal of Clinical and Diagnostic Research, 2013 Introduction: Coronary heart disease is one of the most common cardiac health problem in India. Anti-platelet therapy is the cornerstone in the management of coronary heart disease.
Kishan P.V. +4 more
doaj +1 more source
Adiponectin diminishes platelet aggregation and sCD40L release. Potential role in the metabolic syndrome [PDF]
, 2010 The proinflammatory and proatherogenic mediator, soluble CD40 ligand (CD40L), is increased in the metabolic syndrome (MS) and released from platelets. We hypothesized that adiponectin modulates platelet function, and we sought to evaluate the association
Colina, I. (Inmaculada) +3 more
core +1 more source
Journal of Pharmacological Sciences, 2022 Quinonoid dihydropteridine reductase (QDPR) regenerates tetrahydrobiopterin (BH4), which is an essential cofactor for catecholamine and serotonin (5-hydroxytryptamine, 5-HT) biosynthesis.
Yui Suganuma +6 more
doaj
Platelet Activation and Aggregation Induced by Streptococcus bovis/Streptococcus equinus Complex
Microbiology Spectrum, 2022 Streptococcus bovis/Streptococcus equinus complex (SBSEC) is a common cause of infective endocarditis (IE). For IE-pathogens, the capacity to activate and aggregate platelets is believed to be an important virulence mechanism.
Gustav Pernow +4 more
doaj +1 more source
The glycoprotein IIb/IIIa antagonist c7E3 inhibits platelet aggregation in the presence of heparin-associated antibodies [PDF]
, 1997 Purpose: Heparin-associated antibodies (HAAb), in the presence of heparin, can cause platelet activation and aggregation. The purpose of this study was to assess whether a platelet glycoprotein (GP) IIb/IIIa receptor antagonist, c7E3, would inhibit ...
Liem, Timothy K. +3 more
core +1 more source
Influence of Platelet Aggregation Modulators on Cyclic AMP Production in Human Thrombocytes
Folia Medica, 2018 Background: Cyclic AMP is a powerful inhibitor of platelet aggregation. In the present study we examined the effect of platelet aggregation modulators on cyclic AMP content in human thrombocytes.
Boyanov Krasimir O., Maneva Ana I.
doaj +1 more source
Effects of pentoxifylline on canine platelet aggregation
Veterinary Medicine and Science, 2021 Background Pentoxifylline can decrease platelet function in humans, but the anti‐platelet effects of pentoxifylline in dogs is unknown. The addition of a luciferin–luciferase reagent during platelet aggregometry can induce a dose‐dependent potentiation ...
John M. Thomason +3 more
doaj +1 more source
Revista de la Alad. Asociación Latinoamericana de Diabetes, 2022 Objective: To analyze the expression of TLR7, TLR9, and signaling proteins MyD88 and NF-κB, and their relationship with platelet aggregation in Yucatecan patients with type 2 diabetes.
LucÃa G. González-Espinosa +7 more
doaj +1 more source
Agonist-induced platelet aggregation does not correlate with the varying severity of microangiopathy in patients with Type 2 diabetes mellitus [PDF]
, 1998 We investigated agonist-induced platelet aggregation in 23 age- and sex-matched control subjects and in 74 patients with type 2 diabetes mellitus. Platelet aggregation was measured by a particle counting method using light scattering (LS) and by a ...
core +1 more source
Redox Biology, 2022 Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S–S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively. PDI has been
Lu Wang +6 more
doaj