PKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental Sepsis. [PDF]
PLoS ONE, 2015 Sepsis severity has been positively correlated with platelet dysfunction, which may be due to elevations in nitric oxide (NO) and cGMP levels. Protein kinase C, Src kinases, PI3K and AKT modulate platelet activity in physiological conditions, but no ...
M Elisa Lopes-Pires +5 more
doaj +1 more source
Mechanisms Underlying the Morning Increase in Platelet Aggregation: A Flow Cytometry Study [PDF]
, 1996 ObjectivesMechanisms underlying the morning increase in platelet aggregation produced by arising and assuming the upright posture were studied by examining 1) the expression on the platelet surface of activation-dependent markers; 2) platelet aggregation
Andrews, Neil P. +4 more
core +1 more source
FbsA, a fibrinogen-binding protein from Streptococcus agalactiae, mediates platelet aggregation [PDF]
, 2005 The bacterium Streptococcus agalactiae is an etiologic agent in the pathogenesis of endocarditis in humans. FbsA, a fibrinogen-binding protein produced by this pathogen, is considered an important virulence factor.
Fitzgerald, J Ross +7 more
core +1 more source
Effect of electrolyte on the microstructure and yielding of aqueous dispersions of colloidal clay [PDF]
Soft Matter, 2016, 12, 414-421, 2015 Na-montmorillonite is a natural clay mineral and is available in abundance in nature. The aqueous dispersions of charged and anisotropic platelets of this mineral exhibit non-ergodic kinetically arrested states ranging from soft glassy phases dominated by interparticle repulsions to colloidal gels stabilized by salt induced attractive interactions ...
arxiv +1 more source
The in vitro effect of antirheumatic drugs on platelet function
Platelets, 2020 Several antirheumatic drugs lower the cardiovascular risk among rheumatoid arthritis patients. It is, however, unknown whether inhibition of platelet function contributes to this risk reduction.
Camilla Brødsgaard Nielsen +4 more
doaj +1 more source
The Influence of Haemoglobin A1c Levels on Platelet Aggregation and Platelet Turnover in Patients with Coronary Artery Disease Treated with Aspirin. [PDF]
PLoS ONE, 2015 Hyperglycaemia may attenuate the antiplatelet effect of aspirin and thereby increase the risk of cardiovascular events. We investigated the influence of increased haemoglobin A1c (HbA1c) levels on platelet aggregation and turnover in a large cohort of ...
Søs Neergaard-Petersen +5 more
doaj +1 more source
Novel aspects of platelet aggregation [PDF]
, 2014 The platelet aggregation is an important process, which is critical for the hemostatic plug formation and thrombosis. Recent studies have shown that the platelet aggregation is more complex and dynamic than it was previously thought.
Bilous, V.L. +3 more
core +2 more sources
Colloid aggregation induced by oppositely charged polyions [PDF]
, 2002 The "polymer reference interaction site model" (PRISM) integral equation formalism is used to determine the pair structure of binary colloidal dispersions involving large and small polyions of opposite charge. Two examples of such bidisperse suspensions are considered in detail, namely mixtures of charged spherical colloids and oppositely charged ...
arxiv +1 more source
Reduced platelet activation and platelet aggregation in patients with alcoholic liver cirrhosis
Platelets, 2018 Results from previous studies regarding platelet function in liver cirrhosis are discordant. The aim was to investigate platelet activation and platelet aggregation in patients with alcoholic liver cirrhosis.
Pernille Just Vinholt +6 more
doaj +1 more source
PLATELET AGGREGATION PROFILE AND CARDIOVASCULAR EVENT IN CORONARY HEART DISEASE PATIENTS WITH DUAL ANTIPLATELET [PDF]
, 2016 Platelet aggregation plays an important role in atherosclerosis process in Coronary Heart Disease (CHD) patients. Antiplatelet acts to prevent platelet aggregation and thrombus subsequently. Thrombus will block artery coronaries.
., Carollina +3 more
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