Results 61 to 70 of about 195,699 (241)

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

Advanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng, Shan Xu, Yi Lei, Huizhou He, Runbin Sun, Xingle Jin, Cheneryu Huang, Yuhao Zheng, Jianqing Peng, Lei Tang, Peng Luo, Yi Chen, Shuai Zhang   +12 more
wiley   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source

Function and Platelet Count in Thrombocyte Concentrate (TC) During the Storage [PDF]

, 2015
Background: Evaluation for platelet transfusion is not optimal for this moment even in upstream at theblood center or in downstream at the hospital. The purpose of this study was to determine the effect ofstorage time to changes in pH, platelet count and
Marpaung, E. (Elida), Ritchie, N. K. (Ni), Setiawaty, V. (Vivi), Timan, I. S. (Ina)   +3 more
core  

Avaliação da agregação plaquetária em presença de anticorpos antifosfolípides: anti-β2GP1 e anticardiolipina [PDF]

, 2013
IntroductionThe antiphospholipid syndrome (APS) is an autoimmune condition characterized by recurrent arterial and venous thrombosis, besides obstetric complications.
Aarestrup, Fernando Monteiro, Andrade Azevedo, Maria Regina, de Carvalho, Giuliano Reder, de Mesquita, Harleson Lopes, do Amaral Corrêa, José Otávio   +4 more
core   +2 more sources

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

Evaluation of Anti-Platelet Aggregation Effect of Some Allium Species [PDF]

, 2015
Epidemiologic studies show that the cardiovascular diseases are associated with multiple factors such as raised serum total cholesterol, increased LDL, increased platelet aggregation, hypertension and smoking.
Amidi, Salimeh., Ayatollahi, Seyed Abdolmajid., Kobarfard, Farzad., Lorigooini, Zahra.   +3 more
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Concomitant activation of Gi protein-coupled receptor and protein kinase C or phospholipase C is required for platelet aggregation [PDF]

, 1999
It has recently been suggested that the concomitant activation of two distinct G protein-coupled receptors (Gi and Gq) is essential for platelet aggregation: in fact, the thromboxane A2 synthetic agonist, U46619, which causes the selective activation of ...
Ciampa, Maria Teresa, Favilla, Mara, Gazzaniga, Pier Paolo, Pignatelli, Pasquale, Pulcinelli, Fabio M, Riondino, Silvia   +5 more
core   +1 more source

Butterfly‐Inspired Hierarchical Hybrid Composites for Lightweight Structural Thermal Management Applications

Advanced Functional Materials, EarlyView.
Emulating nature's unparalleled engineering, this work introduces butterfly‐inspired hybrid composites for high‐performance transportation and defense sectors. Leveraging biomimicry, these lightweight composites feature butterfly leg‐inspired hierarchical fibrous assemblies and butterfly wing‐inspired sandwich‐structured architecture, to achieve ...
Nello D. Sansone, Rafaela Aguiar, Mahmoud Embabi, Nichole Cheung, Anthony V. Tuccitto, Nathan R. S. Chang, Matthew Leroux, Patrick C. Lee   +7 more
wiley   +1 more source

CYP2C19*17 Polymorphisms And Platelet Aggregation In Coronary Artery Disease Patients With Clopidgrel [PDF]

, 2017
Background: Clopidogrel is the alternative therapy for patients with Coronary Artery Disease (CAD) that couldn’t use Aspirin as antiplatelet. There’s some factors that contribute to clopidogrel effectiveness, such as obesity, Diabetes Mellitus, Smoking,
Ananda, Yuki, Queljoe, Doddy de, Rochmawati, Ike Dhiah   +2 more
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No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response [PDF]

, 2023
Background: A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A: E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor treatment.
Cremer, Signe E., Faisst, Daniel N., Häggström, Jens, Knold, Mads, Ljungvall, Ingrid, Meurs, Kathryn M., Moller, Jacob E., Olsen, Lisbeth H., Reimann, Maria J., Stern, Joshua A.   +9 more
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