Results 171 to 180 of about 237,328 (413)

Electron Extraction Optimization for Carbon‐Based Hole‐Conductor‐Free Perovskite Photovoltaics With Record 1.41 V VOC

Advanced Materials, EarlyView.
A gradient electron energy level strategy is constructed to reduce voltage losses in planar HTL‐free CsPbI2Br C‐PSCs. This electron extraction optimization enables rapid photogenerated electron extraction and carrier separation, thereby suppressing recombination at the back contact. The resulting PSCs deliver a record VOC of 1.41 V, a high PCE of 17.42%
Zhiqi Li, Xiyun Xie, Zhenhai Ai, Yu Han, Tao Zhu, Ruijie Ma, Heng Liu, Xinhui Lu, Qi Wei, Mingjie Li, Junyan Xiao, Kuan Liu, Zhiwei Ren, Gang Li   +13 more
wiley   +1 more source

Intravenous antiplatelet therapies (glycoprotein IIb/IIIa receptor inhibitors and cangrelor) in percutaneous coronary intervention: from pharmacology to indications for clinical use

Therapeutic Advances in Cardiovascular Disease, 2019
Oral antiplatelet drugs are crucially important for patients with acute coronary syndrome or stable coronary artery disease undergoing percutaneous coronary intervention (PCI).
Davide Capodanno, Rocco P. Milluzzo, Dominick J. Angiolillo   +2 more
doaj   +1 more source

Modeling Platelet P2Y$_1$/$_{12}$ Pathway to Integrin Activation [PDF]

arXiv
Through experimental studies, many details of the pathway of integrin $\alpha_{\rm IIb}\beta_3$ activation by ADP during the platelet aggregation process have been mapped out. ADP binds to two separate G protein coupled receptors on platelet surfaces, leading to alterations in the regulation of the small GTPase RAP1.
arxiv  

Role of Cytoskeletal Dynamics in Platelet Arf6 Activation [PDF]

, 2015
Platelets undergo morphological changes upon activation, such as shape change and aggregation. These changes are known to be the result of actin remodeling, whereas the role of microtubule remodeling has been controversial.
Begley, Brett Taylor
core   +1 more source

Interaction of Oligonucleotides with Gold Nanoparticles: Factors Beyond Electrostatic and Van‐Der Waals Forces

Advanced Materials Interfaces, EarlyView.
The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur, Nicola Cavallini, Debora Ferrari, Laura Fabris   +3 more
wiley   +1 more source

Air-blood interface engineered microfluidic device to mimic shear rate gradient induced human bleeding model [PDF]

arXiv
Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over channel geometry and flow conditions.
arxiv  

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

TKI-Related Platelet Dysfunction Does Not Correlate With Bleeding in Patients With Chronic Phase-Chronic Myeloid Leukemia With Complete Hematological Response

Clinical and Applied Thrombosis/Hemostasis, 2019
Bleeding has been reported in patients with chronic myeloid leukemia (CML) using tyrosine kinase inhibitors (TKIs). In this study, we aimed to evaluate platelet functions and associated bleeding symptoms in patients with CML using TKIs.
Yigit Sener MD, Mufide Okay MD, Seda Aydin MD, Yahya Buyukasik MD, Filiz Akbiyik MD, Zeliha Gunnur Dikmen MD   +5 more
doaj   +1 more source

An Anticoagulant Coating Based on a Block Phosphocholine Copolymer for Potential Applications in Blood Contact Devices

Advanced Materials Interfaces, EarlyView.
Anticoagulant properties are critical for blood‐compatible materials, and anticoagulant coatings are a common key issue for blood‐contacting medical devices. In this study, a block copolymer poly(2‐methacrylenoxyethyl phosphocholine‐b‐glycidyl) (PMPC‐b‐GMA) is synthesized, using reversible addition‐fragmentation chain transfer polymerization (RAFT) and
Xinli Lu, Yahong Kang, Xuebin Wang, Weijie Wang, Changsheng Liu, Hongyan Jiang, Yuan Yuan   +6 more
wiley   +1 more source

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source