Results 231 to 240 of about 223,961 (265)

Inhibition of platelet endothelial cell adhesion molecule-1 synthesis and leukocyte transmigration in endothelial cells by the combined action of TNF-alpha and IFN-gamma.

Journal of Immunology, 1996
Endothelial cell (EC) junctions regulate circulating leukocyte extravasation and infiltration at inflammatory sites. Several lines of evidence show that platelet endothelial cell adhesion molecule-1 (PECAM-1), a specific component of EC junctions, is ...
Y. Rival, A. Maschio, M. Rabiet, E. Dejana, A. Duperray   +4 more
semanticscholar   +1 more source

Platelet endothelial cell adhesion molecule-1 expression modulates endothelial cell migration in vitro.

Laboratory investigation; a journal of technical methods and pathology, 1998
Endothelial cell migration is an important process that occurs during embryonic vasculogenesis and angiogenesis, wound healing, and tumor growth and metastasis, and after denudation injury following angioplasty and bypass grafting. Mechanisms regulating this process involve a complex interplay of cytoskeletal reorganization, cell-cell adhesion, and ...
C S, Kim, T, Wang, J A, Madri
openaire   +1 more source

Platelet–endothelial cell adhesion molecule-1 modulates endothelial migration through its immunoreceptor tyrosine-based inhibitory motif

Biochemical and Biophysical Research Communications, 2003
Coordinated migration of endothelial cells models the remodeling of existing endothelia as well as angiogenesis and vasculogenesis. Platelet-endothelial cell adhesion molecule-1, PECAM-1, a transmembrane endothelial adhesion protein, binds and activates the tyrosine phosphatase SHP-2 via phosphotyrosines 663 and 686.
Dita, Gratzinger, Mark, Barreuther, Joseph A, Madri   +2 more
openaire   +2 more sources

Silencing the expression of platelet endothelial cell adhesion molecule‐1 prevents allogeneic T‐cell cytotoxicity

Transfusion, 2010
BACKGROUND: After solid organ transplantation, the endothelium is the first allorecognition checkpoint of the recipient's immune system. A major player at this interface is the platelet endothelial cell adhesion molecule‐1 (PECAM‐1), which is an immunoglobulin‐like glycoprotein, involved in white blood cell migration, cellular adhesion, and signal ...
Yarúa, Jaimes, Constança, Figueiredo, Rainer, Blasczyk   +2 more
openaire   +2 more sources

Expression of platelet endothelial cell adhesion molecule-1 in red and black endometriotic lesions

Fertility and Sterility, 2004
This immunohistochemical study shows that platelet endothelial cell adhesion molecule-1 (PECAM-1), known to play a role in neoangiogenesis and vascular development, is strongly and homogeneously expressed in endothelial cells lining blood vessels from red and black pelvic endometriotic lesions.
Anne, Van Langendonckt, Julie, Eggermont, Françoise, Casanas-Roux, H Elène, Scholtes, Jacques, Donnez   +4 more
openaire   +2 more sources

Differential Expression of Platelet-Endothelial Cell Adhesion Molecule-1 (PECAM-1) in Murine Tissues

Microcirculation, 1998
To characterize and compare the expression of PECAM-1 in unstimulated and tumor necrosis factor alpha-(TNF-alpha)-stimulated tissues of mice.Binding and non-binding monoclonal antibodies (mAb) were radiolabeled and injected into wild-type mice and mice deficient of P-selectin, CD18, or ICAM-1.
M J, Eppihimer, J, Russell, R, Langley, G, Vallien, D C, Anderson, D N, Granger   +5 more
openaire   +2 more sources

Platelet endothelial cell adhesion molecule-1 expression during mouse postimplantation development.

Cellular and molecular biology (Noisy-le-Grand, France), 1998
With the aim to analyze the ontogeny of the mouse endothelium, monoclonal antibody (mAb) MEC 13.3 was used for the immunohistochemical staining of frozen sections of different stages of mouse embryo development. This mAb specifically recognizes membrane reinforcement of endothelial cells (EC) from mouse blood vessels, indicating the expression of a ...
G, Calabrese, M, Fernandez de Recondo, E, Recondo, R, Wainstok de Calmanovici   +3 more
openaire   +1 more source

Immunolocalization of the cellular adhesion molecules, intercellular adhesion molecule-1 (ICAM-1) and platelet endothelial cell adhesion molecule (PECAM), in human endometrium throughout the menstrual cycle.

Human Reproduction, 1993
S. Tawia, L. Beaton, P. Rogers
semanticscholar   +1 more source

Structural Implications of Platelet Endothelial Cell Adhesion Molecule-1 Polymorphisms

Transplantation, 2008
Vasilis, Kosmoliaptsis, Reyna S, Goodman, Tim R, Dafforn, J Andrew, Bradley, Craig J, Taylor   +4 more
openaire   +2 more sources

Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions

Ca-A Cancer Journal for Clinicians, 2023
Balazs Dome
exaly