Angiogenesis in Platelet Endothelial Cell Adhesion Molecule-1-Null Mice [PDF]
The American Journal of Pathology, 2009 Platelet endothelial cell adhesion molecule (PECAM)-1 has been previously implicated in endothelial cell migration; additionally, anti-PECAM-1 antibodies have been shown to inhibit in vivo angiogenesis. Studies were therefore performed with PECAM-1-null mice to further define the involvement of PECAM-1 in blood vessel formation.
Gaoyuan, Cao +5 more
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Arsenic Exposure Increases Monocyte Adhesion to the Vascular Endothelium, a Pro-Atherogenic Mechanism. [PDF]
PLoS ONE, 2015 Epidemiological studies have shown that arsenic exposure increases atherosclerosis, but the mechanisms underlying this relationship are unknown. Monocytes, macrophages and platelets play an important role in the initiation of atherosclerosis. Circulating
Maryse Lemaire +8 more
doaj +1 more source
THE MOLECULAR ORGANIZATION OF ENDOTHELIAL JUNCTIONS IN VASCULAR PERMEABILITY [PDF]
Euromediterranean Biomedical Journal, 2021 Vascular permeability is an innate function of the circulatory system that regulates the flux of fluid, proteins, and immune cells from blood to tissue.
Angela Bruna Maffione
doaj +1 more source
The platelet endothelial cell adhesion molecule‐1 (PECAM1) contributes to endothelial barrier function [PDF]
FEBS Letters, 1995 In this study we have analyzed the role of the platelet‐endothelial cell adhesion molecule‐1 (PECAM1) in vascular barrier function. PECAM1 is an immunoglobulin gene superfamily member expressed by endothelial cells at the cell boundaries. Macromolecule permeability assays performed on cell monolayers that express native or transfected PECAM1, indicated
Ferrero, Elisabetta +3 more
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Platelet PI3Kγ Contributes to Carotid Intima-Media Thickening under Severely Reduced Flow Conditions. [PDF]
PLoS ONE, 2015 Studies have begun to focus on the emerging function of platelets as immune and inflammatory cells that initiate and accelerate vascular inflammation.
Cuiping Wang +4 more
doaj +1 more source
Materials Today Bio, 2022 The endothelium plays an important regulatory role for cardiovascular homeostasis. Rapid endothelialization of small diameter vascular grafts (SDVGs) is crucial to ensure long-term patency.
Sabrina Rohringer +9 more
doaj +1 more source
Increased levels of soluble forms of E-selectin and ICAM-1 adhesion molecules during human leptospirosis. [PDF]
PLoS ONE, 2017 Leptospirosis is a multisystemic zoonotic disease with infiltration of visceral organs by Leptospira. The capacity of the vascular endothelium to grant immune cell recruitment and activation in target organs during the disease course remains poorly ...
Loic Raffray +5 more
doaj +1 more source
Bleomycin increases neutrophil adhesion to human vascular endothelial cells independently of upregulation of ICAM-1 and E-selectin [PDF]
, 2016 © 2016 Taylor & Francis. Aim of the Study: Bleomycin-induced lung disease is a serious complication of therapy characterized by alveolar injury, cytokine release, inflammatory cell recruitment, and eventually pulmonary fibrosis.
Crooks, Michael G. +4 more
core +1 more source
Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor-Deficient Mice [PDF]
, 2008 Objective—Atherosclerosis is a vascular disease that involves lesion formation at sites of disturbed flow under the influence of genetic and environmental factors.
Arora, Shikha +9 more
core +2 more sources
Increased Endothelial Cell Expression of Platelet–Endothelial Cell Adhesion Molecule-1 during Hyperoxic Lung Injury [PDF]
American Journal of Respiratory Cell and Molecular Biology, 1998 Lung injury is a frequent consequence of oxygen (O2) therapy administered to newborns and adults with respiratory distress. Acute exposure to hyperoxia results in a well-described pathophysiologic response in the lungs. Because inflammation is an important component of pulmonary O2 toxicity, we have an interest in identifying the inflammatory mediators
B, Piedboeuf +5 more
openaire +2 more sources