Results 51 to 60 of about 629,196 (341)

Platelet factor 4 in platelet concentrates.

Journal of the Japan Society of Blood Transfusion, 1984
The release of platelet factor 4 (PF4) from platelets in platelet concentrates (PC) were investigated sequentially in the process of blood collection, and their storage at room temperature for up to 72h with agitation. No appreciable increase in PF4 release was seen immediately after blood collection.
Yuko Ishikawa, Tetsuo Shimizu, Satomi Hibi, Hiromi Tsurumi, Soji Goto, Iwazo Hasegawa, Tsuneo Fukuda, Kanefusa Kato   +7 more
openaire   +2 more sources

Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]

, 2003
Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike, Engelmann, Bernd, Klocke, Antje, Kotzsch, Matthias, Luther, Thomas, Morgenstern, Eberhard, Müller, Ingrid, Preissner, Klaus, Zahler, Stefan, Zieseniss, Susanne   +9 more
core   +1 more source

Temporal Release and Denature of Several Mediators in Pure Platelet-Rich Plasma and Temperature-Induced Platelet Lysates Derived from a Similar Bovine Platelet Concentrate

Veterinary Medicine International, 2022
There is scarce information about bovine platelet-rich plasma/platelet-rich gel (PRP/PRG) and related hemocomponents (HCs), such as platelet lysates (PLs), including growth factor (GF) and cytokine concentrations, and how the stability of these ...
Jorge U. Carmona, Catalina López, Alejandro Ceballos-Márquez   +2 more
doaj   +1 more source

High Glucose, But Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells [PDF]

, 2015
Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases.
Aswin, S. (Soedjono), Jenie, I. M. (Ikhlas), Mulyono, B. (Budi), Soejono, S. K. (Sri)   +3 more
core   +2 more sources

Development of a high-yield expression and purification system for platelet factor 4

Platelets, 2018
Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction characterized by IgG antibodies bound to complexes of platelet factor 4 (PF4) and heparin. The majority of diagnostic tests for HIT rely on an exogenous source of PF4 to identify anti-PF4/
Angela Huynh, Donald M. Arnold, Jane C. Moore, James W. Smith, John G. Kelton, Ishac Nazy   +5 more
doaj   +1 more source

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]

, 2018
Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A., Kaplan, Mark H., Ocana, Jesus A., Pawelzik, Sven-Christian, Romer, Eric, Sahu, Ravi, Travers, Jeffrey B.   +6 more
core   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Expression of Regulatory Platelet MicroRNAs in Patients with Sickle Cell Disease [PDF]

, 2013
Background: Increased platelet activation in sickle cell disease (SCD) contributes to a state of hypercoagulability and confers a risk of thromboembolic complications.
A Abdollahi, A Dixon-McIver, A Osman, A Schedel, A Smolenski, A Tomer, AA Kondkar, AD Blann, AI Badeaux, AJ Saldanha, AM Healy, BM Steele, Claudia Coronnello, D Betel, D Betel, DA Hosack, DP Bartel, DV Gnatenko, EM Novelli, ER Popescu, G Bazzoni, Gregory J. Kato, Guoying Yu, H Bruchova, H Seitz, HA Brittain, I Hers, I Toma, J Villagra, Jen-Tsan Ashley Chi, JF Noronha, JS Mohan, K Joop, K Kaushansky, K Konishi, Kimberly Woodhouse, LL Horstman, LR Queen, M Kannan, M Kertesz, Maria G. Kapetanaki, Mark T. Gladwin, MC Ammons, ML Freedman, ML Jison, MP Hunter, N Chavda, N Raghavachari, Naftali Kaminski, Nalini Raghavachari, P Landry, Panayiotis V. Benos, PV Browne, R Antonucci, R Garzon, R Ross, R Visone, RC Friedman, RJ Berckmans, RL Nachman, RT Schermuly, S Amisten, S Kim, S Masaki, S Mendjan, S Nagalla, Shilpa Jain, SP Lee, Suchitra Barge, T Wun, V Ambros, W Huang da   +71 more
core   +6 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Platelets Give a Running Start to Adult Hippocampal Neurogenesis

Stem Cell Reports, 2019
Exercise boosts neural stem and progenitor cell proliferation and differentiation in the dentate gyrus region of the hippocampus. In this issue of Stem Cell Reports, Leiter et al.
Adam B. Schroer, Alana M. Horowitz, Saul A. Villeda   +2 more
doaj   +1 more source