Results 261 to 270 of about 633,370 (307)
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The Lancet, 1969
The following platelet function tests are discussed: bleeding time, platelet retention tests, platelet aggregation, and radio-immunoassays for platelet release products, such as β thromboglobulin (βTG), and platelet factor 4 (PF4).
J W, ten Cate, S I, de Vries
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The following platelet function tests are discussed: bleeding time, platelet retention tests, platelet aggregation, and radio-immunoassays for platelet release products, such as β thromboglobulin (βTG), and platelet factor 4 (PF4).
J W, ten Cate, S I, de Vries
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Haemophilia, 2000
Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery.
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Platelet function defects comprise a large and heterogeneous group of bleeding disorders that range in severity from mild to severe. Patients may be asymptomatic; however, the majority who are diagnosed present with easy bruising and mucocutaneous bleeding, or with excessive haemorrhage following injury or surgery.
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Platelet antigens and their function
Vox Sanguinis, 2004Based on the detailed study of the antigens that are recog-nized by alloantibodies, for example, polymorphisms on anumber of platelet receptors have been identified andclassified as Human Platelet Antigen (HPA)-systems (http://www.ebi.ac.uk/ipd/hpa/index.html).
H, Deckmyn +3 more
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Disorders of platelet function
Disease-a-Month, 1992Platelets provide for primary hemostasis by forming a hemostatic plug at sites of vascular damage. They also provide a surface for the assembly of the coagulation protein complexes that generate thrombin, serve as a nidus for fibrin clots, and secrete factors involved in wound repair.
J S, Bennett, M A, Kolodziej
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Thrombosis and Haemostasis, 2014
SummaryThis review collects evidence about immune and inflammatory functions of platelets from a clinician’s point of view. A focus on clinically relevant immune functions aims at stimulating further research, because the complexity of platelet immunity is incompletely understood and not yet translated into patient care.
Bode, Christoph +2 more
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SummaryThis review collects evidence about immune and inflammatory functions of platelets from a clinician’s point of view. A focus on clinically relevant immune functions aims at stimulating further research, because the complexity of platelet immunity is incompletely understood and not yet translated into patient care.
Bode, Christoph +2 more
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Cyclooxygenases and platelet functions
2023Cyclooxygenase (COX) isozymes, i.e., COX-1 and COX-2, are encoded by separate genes and are involved in the generation of the same products, prostaglandin (PG)G2 and PGH2 from arachidonic acid (AA) by the COX and peroxidase activities of the enzymes, respectively.
Bruno A. +4 more
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Endothelin and platelet function
Thrombosis Research, 1990The effects of newly discovered vasoconstrictor peptide endothelin was studied on human, rabbit and canine platelet function. Endothelin (0.01 nM-1 microM) did not promote platelet aggregation. In human platelets, endothelin (0.1 microM) did not significantly affect aggregation responses to ADP, collagen, epinephrine, arachidonic acid, PGH2 or thrombin.
E H, Ohlstein +4 more
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Platelet Function in Hyperlipoproteinemia
New England Journal of Medicine, 1974Abstract Platelet function was studied in 17 patients with Type II hyperlipoproteinemia. As compared with 26 normal subjects, platelets from patients with the Type II syndrome aggregated in response to 1/25 the mean concentration of epinephrine, one third the concentration of collagen, and one third the concentration of ADP.
A C, Carvalho, R W, Colman, R S, Lees
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The functional dissonance of platelets
Blood, 2012In this issue of Blood , Cloutier et al answer a long-standing but unappreciated question about the influence of platelets on vascular permeability.[1][1] The role of platelets in responding to vascular injury and the prevention blood loss is very well understood.
Enming Joseph, Su, Daniel A, Lawrence
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Platelet Functions in Dysproteinaemia
Acta Haematologica, 1978Platelet functions were studied in 16 patients with multiple myeloma (MM) and 4 with primary macroglobulinemia (PM). The fall in immunoglobulins on therapy was correlated with the status of platelet function. Effect of incubation of normal platelets with immunoglobulins derived from these patients on kaolin-induced platelet factor 3 (PF3) release was ...
J, Kasturi, A K, Saraya
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