Results 21 to 30 of about 11,537,830 (293)
Cells, 2021 Platelets are conventionally defined as playing a vital role in homeostasis and thrombosis. This role has over the years transformed as knowledge regarding platelets has expanded to include inflammation, cancer progression, and metastasis.
L. Repsold, A. Joubert
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Platelet Membrane Receptor Proteolysis: Implications for Platelet Function
Frontiers in Cardiovascular Medicine, 2021 The activities of adhesion and signaling receptors in platelets are controlled by several mechanisms. An important way of regulation is provided by proteolytic cleavage of several of these receptors, leading to either a gain or a loss of platelet ...
Jiayu Wu +3 more
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Aquaporins in platelet function
Platelets, 2021 Structurally, aquaporins (AQPs) are small channel proteins with monomers of ~ 30 kDa that are assembled as tetramers to form pores on cell membranes. Aquaporins mediate the conduction of water but at times also small solutes including glycerol across ...
Ejaife O. Agbani, Alastair W. Poole
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Tzu Chi Medical Journal, 2022 Platelets play an essential role in primary hemostasis through bleeding and thromboembolism. Thus, the diagnosis or evaluation of impaired hereditary, acquired, and drug-related platelet dysfunction has become imperative.
Chih-Lung Shen, Yi-Feng Wu
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Platelet function defects [PDF]
Haemophilia, 2008 Summary. Inherited defects of platelet function are a heterogeneous group of disorders that can result in bleeding symptoms ranging from mild bruising to severe mucocutaneous haemorrhage. These defects may be classified according to their effect on the various steps of platelet microthrombi formation including initiation, extension and cohesion, or ...
D, Simon, T, Kunicki, D, Nugent
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Influence of Cardiometabolic Risk Factors on Platelet Function
International Journal of Molecular Sciences, 2020 Platelets are key players in the thrombotic processes. The alterations of platelet function due to the occurrence of metabolic disorders contribute to an increased trend to thrombus formation and arterial occlusion, thus playing a major role in the ...
C. Barale, I. Russo
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Sensitivity of Viscoelastic Tests to Platelet Function
Journal of Clinical Medicine, 2020 Viscoelastic tests provide a dynamic assessment of coagulation, by exploring the time to clot formation and the clot strength. Using specific activators or inhibitors, additional factors can be explored, like the fibrinogen contribution to clot strength.
M. Ranucci, E. Baryshnikova
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Myricetin, the main flavonoid in Syzygium cumini leaf, is a novel inhibitor of platelet thiol isomerases PDI and ERp5 [PDF]
, 2020 Background: Flavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. Syzygium cumini is a flavonoid-rich medicinal plant that contains myricetin and gallic acid.
Ayyanar +45 more
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Effect of Prostanoids on Human Platelet Function: An Overview
International Journal of Molecular Sciences, 2020 Prostanoids are bioactive lipid mediators and take part in many physiological and pathophysiological processes in practically every organ, tissue and cell, including the vascular, renal, gastrointestinal and reproductive systems. In this review, we focus
S. Braune, J. Küpper, F. Jung
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Онкогематология, 2014 Platelets are anuclear cell fragments playing important role in hemostasis, termination of bleeding after damage, as well as in pathological thrombus formation. The main action of platelets is the formation of aggregates, overlapping the injury.
M. A. Panteleev, A. N. Sveshnikova
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