Results 21 to 30 of about 620,646 (305)

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

open access: yes, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle   +2 more
core   +1 more source

Evaluation of platelet function in horses undergoing colic surgery using the PFA-100 platelet function analyser

open access: yesVeterinární Medicína, 2015
Acute colic in horses, especially presentations requiring surgical correction, such as large colon volvulus, very often involves defective or excess platelet activation.
A. Iwaszko-Simonik, S. Graczyk
doaj   +1 more source

Antiplatelet therapy – platelet function test for platelet response assessment [PDF]

open access: yesБългарска кардиология
Dual antiplatelet therapy is the main pharmacological mechanism used to suppress platelet function in order to prevent thrombotic complications following percutaneous coronary angioplasty.
D. Dineva, Е. Doncheva, I. Paskaleva
doaj   +3 more sources

Platelet function and platelet lipid composition in the dyslipoproteinemias

open access: yesJournal of Lipid Research, 1980
Blood platelets from eight patients with hyperbetalipoproteinemia (type II) were more reactive to aggregating agents in vitro than those of 13 type IV patients or 12 normal subjects. Platelets of two patients with abeta-lipoproteinemia were also slightly
K M Shastri, A C Carvalho, R S Lees
doaj   +1 more source

Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline

open access: yesPlatelets, 2021
Light transmission aggregometry (LTA) is considered the gold standard method for evaluation of platelet function. However, there are a lot of variation in protocols (pre-analytical procedures and agonist concentrations) and results.
I.C.A. Munnix   +17 more
doaj   +1 more source

Platelet count and function in umbilical cord blood versus peripheral blood in term neonates

open access: yesPlatelets, 2021
Platelet function in neonates is sparsely investigated. The majority of previous studies investigated platelets in umbilical cord (UC) blood rather than in peripheral blood. We included 20 term neonates and sampled UC blood and peripheral blood within 20 
Alexander K. Grevsen   +3 more
doaj   +1 more source

The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function [PDF]

open access: yes, 2011
Background: Thiol isomerases are a family of endoplasmic reticulum enzymes which orchestrate redox-based modifications of protein disulphide bonds. Previous studies have identified important roles for the thiol isomerases PDI and ERp5 in the regulation ...
Bicknell, Andrew B.   +5 more
core   +1 more source

Platelet dysfunction and inhibition of multiple electrode platelet aggregometry caused by penicillin

open access: yesThrombosis Journal, 2010
Beta-lactam antibiotics, e.g. penicillin, may inhibit platelet function and lead to reduced response in light transmission aggregometry and adhesion. However, influence on platelet function tests more commonly used in clinical practice, such as multiple ...
von Beckerath Nicolas   +4 more
doaj   +1 more source

Expression of ADP receptor P2Y12, thromboxane A2 receptor and C-type lectin-like receptor 2 in cord blood-derived megakaryopoiesis

open access: yesPlatelets, 2021
The ADP receptor P2Y12, the thromboxane A2 receptor (TXA2R) and the C-type lectin-like receptor 2 (CLEC-2) mediate platelet activation by different mechanisms. Only little is known about the expression of the receptors in human megakaryopoiesis.
Catharina Gerhards   +6 more
doaj   +1 more source

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP. [PDF]

open access: yes, 2017
Platelet activation in response to stimulation of the Protease Activated Receptor 4 (PAR4) receptor differs by race. One factor that contributes to this difference is the expression level of Phosphatidylcholine Transfer Protein (PCTP), a regulator of ...
Bray, Paul F.   +5 more
core   +3 more sources

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