Results 71 to 80 of about 274,208 (297)

The Laboratory Tests for Platelet Function

Eurasian Journal of Medicine, 2019
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Aves Editorial Aves Editorial
doaj  

Platelet dysfunction and inhibition of multiple electrode platelet aggregometry caused by penicillin

Thrombosis Journal, 2010
Beta-lactam antibiotics, e.g. penicillin, may inhibit platelet function and lead to reduced response in light transmission aggregometry and adhesion. However, influence on platelet function tests more commonly used in clinical practice, such as multiple ...
von Beckerath Nicolas, Okrojek Rainer, von Beckerath Olga, Schulz Christian, Massberg Steffen   +4 more
doaj   +1 more source

Haematalogical investigations in children [PDF]

, 2009
The haematology laboratory is able to perform a number of tests to help establish the cause of illness in children. The full blood count (FBC, also known as a complete blood count, CBC) is one of the most basic blood tests performed on children ...
Chalmers, E.A., Halsey, C.
core  

Platelet function tests using platelet aggregometry: need for repetition of the test for diagnosis of defective platelet function

Platelets, 2003
Four hundred and ninety seven patients were referred to our center for platelet aggregation studies because of spontaneous mucocutaneous bleeds. All these patients had normal complete blood count, platelet count and peripheral smears except in ten patients of Bernard Soulier Syndrome where platelet count was marginally reduced in the presence of giant ...
K, Ghosh, S, Nair, B, Kulkarni, A, Khare, S, Shetty, D, Mohanty   +5 more
openaire   +2 more sources

Platelet function testing: dead or alive [PDF]

Journal of Thrombosis and Haemostasis, 2018
Essentials Pharmacodynamic response to antiplatelet medication is heterogeneous. Platelet reactivity to dual antiplatelet therapy was analyzed by three platelet function assays. The prevalence of high and low platelet reactivity differed significantly between assays.
Helten, C., Naguib, D., Dannenberg, L., Pöhl, M., Ayhan, A., Hohlfeld, T., Levkau, Bodo, Kelm, M., Zeus, T., Polzin, A.   +9 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Effects of pH and concentration of sodium citrate anticoagulant on platelet aggregation measured by light transmission aggregometry induced by adenosine diphosphate

Platelets, 2018
The 2013 ISTH-SSC guidelines for the standardization of light transmission aggregometry (LTA) were largely based on expert consensus, as studies directly comparing LTA methodologies were lacking.
Ksenia Germanovich, Eti Alessandra Femia, Chun Yan Cheng, Natalia Dovlatova, Marco Cattaneo   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Study of liver function test, renal function test and platelet count in hypertensive disorders of pregnancy [PDF]

New Indian Journal of OBGYN
Background: The World Health Organization (WHO) systematically reviews maternal mortality worldwide, and in developed countries, 16 percent of maternal deaths were due to hypertensive disorders.
Indrani R, Chandana Ray Das
doaj   +1 more source

Effects of tranexamic acid on platelet function and thrombin generation (ETAPlaT): WOMAN trial sub-study. [PDF]

, 2016
Background. Postpartum haemorrhage (PPH) is a leading cause of maternal death. Tranexamic acid (TXA) has the potential to reduce bleeding and a large randomized placebo controlled trial of its effect in women with PPH (The WOMAN trial) is underway.
Beaumont, Danielle, Cenameri, Saimir, Dallaku, Kastriot, Delius, Maria, Edwards, Phil, Gliozheni, Orion, Mansmann, Ulrich, Roberts, Ian, Shakur, Haleema, Siegmund, Braun, Tasha, Ilir   +10 more
core   +2 more sources