Results 131 to 140 of about 102,308 (347)

Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy

Journal of Anatomy, Volume 242, Issue 1, Page 29-49, January 2023., 2023
Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone, Gerges Abdelsayed, Fianait Bligh, Fatma Al Qattan, Saifullah Syed, Prateepan Varatharajullu, Augustin Msellati, Daniela Mwipatayi, Maimoona Azhar, Andrew Malone, Saulat H. Fatimi, Claire Conway, Aamir Hameed   +12 more
wiley   +1 more source

Lysosomal Membrane Glycoproteins in Platelets [PDF]

Thrombosis and Haemostasis, 1992
Hans Clevers, Marcel J Metzelaar
openaire   +4 more sources

Systemic lupus erythematosus and cardiovascular disease

Journal of Internal Medicine, Volume 293, Issue 1, Page 48-62, January 2023., 2023
Abstract The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment and care, but cardiovascular disease (CVD) still remains an important clinical problem, since the risk of CVD in SLE is much higher than among controls.
Johan Frostegård
wiley   +1 more source

Platelet Membrane-Coated Nanoparticles Target Sclerotic Aortic Valves in ApoE−/− Mice by Multiple Binding Mechanisms Under Pathological Shear Stress

International Journal of Nanomedicine, 2020
Hongbo Yang, 1,* Yanan Song, 1,* Jing Chen, 1,* Zhiqing Pang, 2 Ning Zhang, 1 Jiatian Cao, 1 Qiaozi Wang, 1 Qiyu Li, 1 Feng Zhang, 1 Yuxiang Dai, 1 Chenguang Li, 1 Zheyong Huang, 1 Juying Qian, 1 Junbo Ge 1 1Department of Cardiology, Zhongshan Hospital,
Yang H, Song Y, Chen J, Pang Z, Zhang N, Cao J, Wang Q, Li Q, Zhang F, Dai Y, Li C, Huang Z, Qian J, Ge J   +13 more
doaj  

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Efeito protetor de antagonista das gliproteínas IIb/IIa nas alterações hepáticas e pulmonares secundárias à isquemia e reperfusão do fígado em ratos Protective effects of an inhibitor of glycoprotein IIb/IIIa in the hepatic and pulmonary disturbances secondary to ischemia and reperfusion injury of rat’s liver

Arquivos de Gastroenterologia, 2007
RACIONAL: A lesão de isquemia e reperfusão hepática é um evento comum e responsável por considerável morbidade e mortalidade. OBJETIVO: Avaliar efeitos de inibidor da glicoproteína IIb/IIIa, cloridrato de tirofiban, nas alterações hepáticas e pulmonares ...
Leonardo F. Canedo, Marcel Autran C. Machado, Ana M. M. Coelho, Sandra N. Sampietre, Telesforo Bachella, Marcel C. C. Machado   +5 more
doaj   +1 more source

Synthetic Biology‐Based Engineering Cells for Drug Delivery

Exploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi, Shuangshuang Hu, Xindi Qian, Wenlu Yan, Yaping Li   +4 more
wiley   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

Exploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

Combination of Autologous Protein-Rich Fibrin and Bone Graft: An Invaluable Option for Reconstruction of Segmental Mandibular Defects

Philippine Journal of Otolaryngology Head and Neck Surgery, 2013
Dear Editor,   Reconstruction of mandibular defects resulting from ablative surgery for benign and malignant tumors remains a reconstructive challenge.
Adrian F. Fernando, Joselito F. David
doaj   +1 more source

Riding a Vascular Time Train to Spatiotemporally Attenuate Thrombosis and Restenosis by Double Presentation of Therapeutic Gas and Biomacromolecules

Exploration, EarlyView.
This project develops a biomimetic stent coating with a double presentation of therapeutic biomacromolecule VEGF and therapeutic gas NO, which spatiotemporally promotes vessel repair including promoting rapid re‐endothelialization, effectively preventing thrombosis, suppressing inflammation and restenosis.
Jingdong Rao, Di Suo, Qing Ma, Yongyi Mo, Ho‐Pan Bei, Li Wang, Chuyang Y. Tang, Kai‐Hang Yiu, Shuqi Wang, Zhilu Yang, Xin Zhao   +10 more
wiley   +1 more source